This issue of Medical Clinics of North America, guest edited by Dr. Anne Marie Ditto, is devoted to Allergy and Immunology for the Internist. Articles in this outstanding issue include:: Approach to the patient with eosinophilia; Approach to the patient with venom allergy; Anaphylaxis; Drug allergy:: A guide for the internist; Food allergy in adults:: presentations, evaluation and treatment; Atopic dermatitis in adults:: role of the allergist; Asthma in adults; Eosinophilic Esophagitis (EOE)/Eosinophil-associated Gastrointestinal Disorders (EGID) presentation in adults; Immunodeficiency:: approach to the patient with frequent infections; Approach to the patient with hives; Allergic contact dermatitis in adults; Cough:: when is it no longer an Upper Respiratory Infection?; Approach to the patient with allergic rhinitis:: testing and treatments; and Mast cell activation syndrome. A CME program is also available for this title.