In this issue of Veterinary Clinics:: Small Animal Practice, guest editors Drs. M. Katherine Tolbert and Sara Jablonski bring their considerable expertise to the topic of Gastroenterology. Gastrointestinal (GI) disorders represent one of the most prevalent clinical presentations in small animal practice, with veterinarians routinely encountering conditions ranging from acute diarrhea to swallowing disorders and protein-losing enteropathies. As clinical approaches evolve, this issue serves as both an essential reference for managing todays cases and a roadmap for navigating future advances in companion animal gastroenterology.