In this issue of Physical Medicine and Rehabilitation Clinics, guest editors Drs. Udai Nanda and Miriam Segal bring their considerable expertise to the topic of Headache Management. Early accurate diagnosis and prompt treatment are essential in symptomatic management and prevention of the chronification of headache. Multidisciplinary team-based rehabilitative strategies have been shown to be beneficial in the management of headache disorders, including refractory and complex cases. PM&R approaches aim to enhance and restore functional ability and quality of life, and this issue provides high-quality evidence-based guidance to help you provide effective headache management at every stage of the care continuum.