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The Effects of Low and Very Low Dose of Ionizing Radiation on Human Health

Proceedings of the First International Symposium on The Effects of Low and Very Low Doses of Ionizing Radiation on Human Health, Versailles, France, 17-18 June 1999, ICS 1203

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Opis
The growing knowledge about the mechanisms of carcinogenesis and the critical analysis of the assumption on which the no-threshold linear relation is based have advanced, but dose-effect relations must be found which optimize the overall epidemiological and experimental data. It is abundantly clear that the standards that will be enforced upon the entry into the force of the International directive no longer enjoy the scientific justifications which made them credible, and that concepts like collective dose and the ALARA (As Low As reasonably Achievable) principle are obsolete. Yet this merely raises, with even greater sharpness, the key question:: what can replace them? In this respect, research on the influence of variations in natural irradiation on cancer frequently represent a vital source of information. Radiological protection has entered what some call a turbulence zone, others a renewal. The dogmas on which it lived for more than two decades have been questioned, giving the medical and scientific community a dual responsibility.
Szczegóły produktu
Churchill Livingstone
48075
9780444505132
9780444505132

Opis

Rok wydania
2000
Numer wydania
1
Oprawa
twarda
Liczba stron
560
Waga (g)
1111
  • 1. Opening address and key note papers.

    1.1. Radiation risks in perspective: Radio-induced cancer among cancer risks (M. Tubiana). 1.2. Control of low level radiation exposure: Time for a change? (R. Clarke). 1.3. European Union facing radioprotection standards (J. Cousaget, P. Pellerin). 1.4. Regulation of low level radiation exposure (M. Gustaffsson). 1.5. Risk estimates for radiation induced cancer - the epidemiological evidence (A.M. Kellerer). 1.6. Genomic instability after low dose irradiation: Relationship to cell stress and implications for radiation protection (C. Mothersill, C. Seymour). 1.7. Molecular mechanisms of radiation carcinogenesis and the linear, non-threshold dose response model of radiation risk estimation (K.R. Trott, M. Rosemann). 1.8. Synthesis and conclusion (R. Masse).

    2. Models and controversies in radiation carcinogenesis.

    2.1. Influence of very low doses of ionizing radiation on life span and immune system in mice (M. Courtade et al.). 2.2. Non-linearity between dose and cancer risk for internally deposited alpha and beta emitters in animals (P. Duport). 2.3. Biological effect of K-events induced by radiations (A. Chetioui et al.). 2.4. Radioadaptive response in human lymphocytes (R.H. Weissenbök, S. Pfandler, C.M. Fleck).

    3. Chernobyl effects.

    3.1. The psychological problems of the social adaption of Chernobyl nuclear power station accident recovery workers (N.A. Alieva et al.). 3.2. The influence of external and internal chronic exposure to low doses on organism of the animals kept in Chernobyl exclusion zones (N15) (M.Y. Alesina). 3.3. The prevention and correction of radiation induced disturbances in experimental animals under conditions of chronic irradiation in low doses (N16) (M.Y. Alesinaet al.). 3.4. Medical problems of Chernobyl nuclear power; station and shelter (V. Bebeshko et al.). 3.5. Some aspects of low radiation doses on human after the Chernobyl NPP accident (A.Y. Romanenko, Y.I. Bomko).

    4. Radon and mining.

    4.1. Is residential radon dangerous? (K. Becker). 4.2. Lung cancer risk at low exposures among Czech miners (L. Tomásek, V. Plaek, A. Heribanová). 4.3. Lung cancer induction in rats after exposure to radon progeny: The complex interplay between cumulative exposure and exposure rate (G. Monchaux, J.-P. Morlier).

    5. Natural radiation.

    5.1. Soil-to-plant 226 Ra concentration ratio in elevated natural radiation areas in Iran (S.M.R. Aghamiri, M.R.D. Seaward, M. Beitollahi). 5.2. Variations in natural background gamma irradiation throughout Spain (E. Suárez Mahou et al.). 5.3. An assessment of external radiation exposure based on environmental monitoring data (I. Popescu et al.). 5.4. Dose estimate and risk assessment due to the ingestion of 226 Ra, 228 Ra and 222 Rn in drinking water supplies of Săo Paulo State - Brazil (J. de Oliveira et al.). 5.5. How can exposure to indoor radon be reduced? (S.M.R. Aghamiri, M.R.D. Seaward).

    6. Low doses risks.

    6.1. Potential occupational radiation risk (R.E. Lapp). 6.2. Variation of the air crew exposure to cosmic radiation (F. Spurny, A. Malusek). 6.3. Effects of low dose neutrons applied at a very low dose rate on human melanoma cells (. Dionet et al.). 6.4. The effect of low dose whole body irradiation on the growth of sarcoma-180 solid tumor in mouse (Y.-S. Kim, S.-C. Yoon). 6.5. Low dose radon as alternative therapy for chronic illness (B. Erickson). 6.6. Hereditary effects in offspring of the first generation after irradiation of one and both parents: Experimental studies (I. Nefyodov, I. Nefyodova, G. Palyga).

    7. Molecular biological mechanisms.

    7.1. Further investigations into the validity of minisatellites as a new tool to monitor low-dose radiation exposure? (B. Le Guen et al.). 7.2. Lymphocyte response in human population and its antioxidant protection against low doses of ionizing radiation (G.J. Köteles et al.). 7.3. Epidemiology, molecular cellular biology and occupational radiation exposure limits (M. Pollycove, L.E. Feinendegen). 7.4. Ukranian nuclear workers: immune function under low-dose exposure (D. Bazvka, N. Beliaeva, C. Bruslova). 7.5. Biological responses after low dose from technetium 99m labeled radiopharmaceuticals (N. Jacquet et al.). 7.6. Studies on the adaptive response: Modifications in people professionally exposed to low doses and search for a transmissible conditioning factor (N.B. Akhmatullina et al.). 7.7. Radiation induced proteins as a test for specific radiation damage (T. Marinova, R. Georgieva, I. Roupova). 7.8. The combined influence of 37 Cs and heavy metals at the cells viable in vitro (M.V. Naboka, G.Y. Lavrenchuk, L.Y. Halchinsky). 7.9. Radio-adaptive survival response in mice-suppression of p53 accumulation after x-irradiation by small dose pre-irradiation in c57bl/ 6 mice- (M. Yonezawa et al.).

    8. Epidemiological data.

    8.1. Carcinogenic effects of low radiation doses; an epistemologically insoluble problem (G.Walinder). 8.2. Analyses of dose exposure for personnel of NPP Kozloduy for the period: 1987-1997 (M. Christova et al.). 8.3. Studies on epidemiology of chromosome aberrations induced in human lymphocytes for indicating contamination of radiation and radiomimetic chemical agents (T. Que et al.). 8.4. Random coincidence - the connection between experiments on radiation adaption and epidemiological data? (C.M. Fleck, S. Pfandler).

    9. Effects on thyroid diseases.

    9.1. Thyroid neoplasia in Mures county after Chernobyl accident: 10 years follow-up (S. Salagean, R. Burkhardt, I. Mocsy). 9.2. Physiological factors in the analysis of radiation-induced thyroid cancer (E. Parshkov et al.). 9.3. An assessment of occupational exposure to I-131 (E.S. Natera, D. Napenas, E.B. Duran). 9.4. Low level irradiation and thyroid diseases epidemiology in Lithuania (T. Nedveckaite et al.).

    10. LNTcontroversies.

    10.1. LNT Hypothesis (E. Roth). 10.2. Organizing and applying the extensive data that contradict the LNT (J.B. Muckerheide). 10.3. Repair of multiple break chromosomal damage - Its impact on the use of the linear quadratic model for low and very low dose rates (B.E. Leonard). 10.4. Resolving the controversy over beneficial effects of ionizing radiation (J.M. Cuttler). 10.5. The effects of low and very low doses of ionising radiation on human health (Y. Nouailhetas).

    11. Neutron and X-ray effects.

    11.1. Persistent demise in progeny of colonies of v-79 cells after x-irradiation (M. Jamali, A.A. Farshad, K.R. Trott). 11.2. Cancer risk assessment among medical X-ray workers in China (J.X. Wang et al.). 11.3. Long-term hematopoietic stem cell effects in mice irradiated with 1 Gy at different stages of development (T. Grande, F. Varas, J.A. Bueren). 11.4 Combined effects of atomic radiation and other agents in Hiroshima and Nagasaki (Y. Nishiwaki).

    12.Working conditions.

    12.1. The experiences in practicing of the radiation protection measures based on ICRP recommendation in Taiwan (Y.C. Luan, W.L. Chen, W.K. Wang). 12.2. Radiation - hygiene assessment of working conditions in Kozloduy NPP (N. Shopov et al.). 12.3. Biomonitoring of radiation workers in Belgium: results of large scale cytogenetic studies using the micronucleus-centromere assay (H. Thierens et al.). 12.4. Cytogenetic effects study of in vitro irradiation in peripheral blood lymphocytes of persons working with ionizing radiation (V. Hadjidekova et al.). 12.5. Effective dose conversion coefficients for external exposure from radionuclides in the atmosphere (J.-K. Lee, J.-K. Chang).
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