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ICRP Publication 100: Human Alimentary Tract Model for Radiological Protection

ICRP Publication 100: Human Alimentary Tract Model for Radiological Protection

9780080450636
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Opis
Publication 100 provides a Human Alimentary Tract Model (HATM) to complement the Publication 66 Human Respiratory Tract Model (HRTM), published in 1994. Both models replaced Publication 30 (1979) models, which were developed specifically for the calculation of doses from occupational exposures to radionuclides. An important aspect of both the HATM and HRTM is their treatment of intakes by children as well as male and female adults and hence their applicability to environmental as well as occupational exposures. Another important development in both models is the specific calculation of doses to target regions containing cells considered to be susceptible to cancer induction.
Szczegóły produktu
Saunders
33143
9780080450636
9780080450636

Opis

Rok wydania
2007
Numer wydania
1
Oprawa
miękka foliowana
Liczba stron
250
Waga (g)
413
  • 1. INTRODUCTION

    1.1. The purpose of this report

    1.2. Model used in ICRP Publication 30

    1.3. The need for a new model

    1.4. Model development

    1.5. Structure of the report

    2. ANATOMY AND PHYSIOLOGY OF THE ALIMENTARY TRACT SYSTEM

    2.1. Introduction

    2.2. General features

    2.3. Alimentation

    2.4. Vascular supply and drainage

    2.5. Micro-anatomy of the alimentary tract

    2.6. Epithelia of the alimentary tract

    3. ABSORPTION, RETENTION, AND SECRETION OF RADIONUCLIDES IN THE HUMAN ALIMENTARY TRACT

    3.1. Introduction

    3.2. Radionuclide absorption

    3.3. Radionuclide retention

    3.4. Radionuclide secretion

    3.5. Examples used in this report

    4. RADIATION EFFECTS

    4.1. Introduction

    4.2. Target cells

    4.3. Radiation-induced cancers in humans

    4.4. Tissue damage

    5. DESCRIPTION OF THE MODEL

    5.1. Overview

    5.2. Main differences from the ICRP Publication 30 model

    5.3. Details of the model structure

    5.4. Radionuclide-specific examples of the use of the model

    6. TRANSIT TIMES THROUGH THE ALIMENTARY TRACT

    6.1. Introduction

    6.2. Mouth

    6.3. Oesophagus

    6.4. Stomach

    6.5. Small intestine

    6.6. Colon and rectum

    6.7. Transfer coefficients

    6.8. Uncertainty and variability

    7. MORPHOMETRY AND DOSIMETRY

    7.1. Introduction

    7.2. Morphometry

    7.3. Dosimetry

    8. USE OF THE MODEL

    8.1. Introduction

    8.2. Examples of doses using the HATM

    8.3. Uncertainties

    8.4. Key features of the HATM

    ANNEX A: EMBRYOLOGY AND ANATOMY OF THE HUMAN ALIMENTARY TRACT

    A.1. Introduction

    A.2. Embryology of the human alimentary tract

    A.3. General overview of the postnatal alimentary tract

    A.4. Oral cavity, pharynx, and associated structures

    A.5. Oesophagus

    A.6. Stomach

    A.7. Liver, biliary tree, and pancreas

    A.8. Small intestine

    A.9. Large intestine

    A.10. Rectum and anal canal

    ANNEX B: PHYSIOLOGY OF THE HUMAN ALIMENTARY TRACT

    B.1. Introduction

    B.2. Physiology of alimentary tract motility

    B.3. Physiology of blood and lymph circulation in the alimentary tract

    B.4. Inputs and secretions in the alimentary tract

    B.5. Bacterial flora in the alimentary tract

    B.6. Digestion, absorption, and retention in the gastrointestinal tract

    ANNEX C: REVIEW OF TRANSIT TIMES THROUGH MAJOR SEGMENTS OF THE ALIMENTARY TRACT

    C.1. Mouth

    C.2. Oesophagus

    C.3. Stomach

    C.4. Small intestine

    C.5. Large intestine

    ANNEX D: ABSORPTION AND RETENTION OF RADIONUCLIDES

    D.1. Introduction

    D.2. Oral cavity

    D.3. Oesophagus

    D.4. Stomach

    D.5. Small intestine

    D.6. Large intestine

    D.7. Appendix

    ANNEX E: CONSISTENCY BETWEEN THE HATM AND THE HRTM

    ANNEX F: ABSORBED FRACTIONS FOR ELECTRON EMISSIONS

    REFERENCES

    ERRATA TO ICRP PUBLICATION 95
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