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This volume provides a summary review of all recently published and ongoing research initiatives related to Tourette Syndrome. The latest research is presented in a clinical context, and controversial issues are fully discussed using an evidence-based approach. These issues include the prevalence of TS, the nature of the TS phenotype, the role of autoimmunity in the development of TS, the role of comorbidity in functional outcomes of TS patients, and approaches to identifying the TS gene/genes.
Chapters describe recent advances in neuroimaging, genetics, and treatment. The book includes extensive discussions of co-morbid disorders:: obsessive-compulsive disorder, attention deficit hyperactivity disorder, mood disorders, and tics.
Opis
CLINICAL PHENOMENOLOGY
Phenomenology and Natural History of Tics
James F. Leckman
CO-MORBID DISORDERS
ADHD
Martha Bridge Denckla
Obsessive Compulsive Disorder
Euripedes C. Miguel
Mood and Behavioral Disorders
Mary M. Robertson
Tics Associated with Other Disorders
Joseph Jankovic
NEW FINDINGS IN BASIC NEUROSCIENCES
Preclinical Models Relevant to TS
Neal R. Swerdlow
Neurobiology of Basal Ganglia and TS:: Neuroanatomy
John W. Mink
Neurobiology of Basal Ganglia and TS:: Neurotransmitters and Neurochemistry
Roger L. Albin
NEUROIMAGING AND NEUROPHYSIOLOGY
Motor Cortex Inhibition
Donald L. Gilbert
Functional Neuroimaging of Tourette Syndrome:: Advances and Future Directions
Tracy Butler, Emily Stern, and David Silbersweig
GENETICS AND MOLECULAR BIOLOGY OF TS
A Genome-Wide Scan and Fine Mapping in Tourette Syndrome Families
David L. Pauls
Genetic Database; Family Studies; Best Estimate
William M. McMahon, Cornelia L. Illmann, and Meghan M. McGinn
Genes and TS:: What Will They Tell Us? Scientific, Ethical, and Social Implications
Nancy M.P. King
IMMUNOLOGY AND TS
Preclinical and Clinical Evidence of CNS Infectious Etiology
Tanya K. Murphy
PANDAS:: Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS):: Overview of the Hypothesis
Gavin Giovannoni
Neuroimmunological Studies in TS and PANDAS
Harvey S. Singer
PANDAS:: To Treat or Not to Treat?
Robert A. King
EPIDEMIOLOGY AND DEFINING THE PHENOTYPE
Syndrome Definitions and Epidemiology
Lawrence Scahill
ADVANCES IN TREATMENT
Treatment of Tics
Leon S. Dure IV and Jennifer DeWolfe
Pharmacological Treatment of ADHD and Tics
Kenneth D. Gadow
Treatment of Comorbid OCD, Mood, and Anxiety Disorders
Barbara J. Coffey
Pharmacological Treatment of Explosive Outbursts
Cathy L. Budman
Behavioral Therapy for Tic Suppression
John Piacentini and Susanna Chang
Behavioral Therapy:: Other Interventions
Douglas W. Woods
Behavioral Neurosurgery
Donald Malone
Future and Alternative Therapies in Tourettes Syndrome
Roger Kurlan
Indeks: 84746
Autor: Michael T Compton
A Guide for Patients and Their Families
Indeks: 90155
Autor: Eric D. Perakslis
Understanding the Benefit-Risk Patient-Provider Framework