In this issue of Child and Adolescent Psychiatric Clinics, guest editors Drs. Deborah R. Simkin and L. Eugene Arnold bring their considerable expertise to the topic of Complimentary and Integrative Medicine Part II:: Treatment Interventions. In this second of two related issues, top experts discuss complementary and integrative medicine in psychiatric care, with a special focus on alternative treatment interventions such as music, art, and dance therapy; lifestyle modifications; managing the physical environment factors; spirituality and stress; the microbiome; and more.