Antimicrobial resistance (AMR) challenges the treatment of clinical infections. Despite the decline in infectious diseases mortality rates, infections are more difficult to eliminate or contain in the host, resulting in poorer outcomes to treatment, longer hospital inpatient stays, and increased mortality.Written by international experts in the field and supported by the review of the available evidence, including example case studies, Antimicrobial Stewardship provides a practical how-to guide on this growing area. Divided into three sections, the first sets the scene, looking at the key problems of antimicrobial resistance. Section two examines and identifies the key components of an antimicrobial stewardship program. Finally, the book explores specialist areas of antimicrobialstewardship ranging from antimicrobial pharmacokinetics and dynamics, to near patient testing, and infection biomarkers.Antimicrobial Stewardship will be a valuable and practical resource for infection trainees, as well as specialists from the medical, pharmacy, and nursing professions.
Preface; Abbreviations; Section 1: Setting the scene and starting up:; The international and national challenges faced in ensuring the prudent use of antimicrobials; What are the principles and goals of antimicrobial stewardship; Managing behaviours: Social, cultural and psychological aspects of antibiotic prescribing and use; Implementing an Antimicrobial Stewardship Programme; Section 2: Components of an Antimicrobial Stewardship Program; Managing antimicrobials on the shop floor; Measuring antibiotic consumption and outcomes; Measuring and feeding back stewardship; Information technology in antimicrobial stewardship; Section 3: Special Areas in Antimicrobial Stewardship; Pharmacokinetic and Pharmacodynamic Principles of Antimicrobials; The Role of the Microbiology Laboratory in Antimicrobial Stewardship; Antimicrobial Stewardship in the Immuno-Compromised Patient; Antimicrobial Stewardship in the Intensive Care Setting; Surgical Prophylaxis; Antimicrobial Stewardship in Paediatrics; Stewardship in the primary care and long term care setting; Antifungal Stewardship; Near Patient Testing and infection biomarkers; Antimicrobial Stewardship in a Resource Poor Setting;
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