The human gut is the natural habitat for a diverse and dynamic microbial ecosystem having an important impact on health and disease. Bacteria have lived in and on animal hosts since multicellular life evolved about 1 billion years ago. Hosts provide habitat and nutrition to the microbial communities and derive many benefits from their guests that contribute with metabolic (recovery of energy and nutrients), defensive (barrier effect against invaders) and trophic (immune regulation, neuro-endocrine development) functions. Several disease states or disorders have been associated with changes in the composition or function of the enteric microbiota, including inflammatory bowel diseases, obesity and the metabolic syndrome. Probiotics and prebiotics can be used to improve symbiosis between enteric microbiota and host, or correct states of dysbiosis.
Microbial Communities Host-Microbe Interactions in the Gut Composition of the Human Enteric Microbiota Acquisition of the Enteric Microbiota Dysfunction of the Enteric Microbiota Therapeutic Manipulation of the Enteric Microbiota References Author Biography
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Proceedings of the Third International Conference of Comparative Physiology and Biochemistry held in Kwa-Zulu Natal, South Africa between 7 and 13 August 2004, ICS 1275