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Renal Physiology

Renal Physiology

Mosby Physiology Monograph Series (with Student Consult Online Access)

9780323034470
176,35 zł
158,71 zł Zniżka 17,64 zł Brutto
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Opis
The Mosby Physiology Monograph Series offers the fundamentals of body systems physiology in a clear and concise manner. Each volume in the series is written by experts in the field for an authoritative, yet readable introduction to the physiology relevant to a particular organ system.

This new 4th edition of Renal Physiology offers::

. Clear, accurate and up-to-the-minute coverage of the physiology of the renal system focusing on the needs of the student.
. Pathophysiology content throughout that serves as a bridge between normal function and disease.
. Integrated student-friendly tools, including learning objectives, overview boxes, key words and concepts, chapter summaries, self-study problems, clinical cases with questions and explained answers, clinical boxes and molecular boxes.
. Access to Student Consult ®!

www.studentconsult.com is an innovative website that allows you to build a personalized, fully integrated, online library, where youll find the entire contents of every STUDENT CONSULT title purchased, integration links to bonus content in other STUDENT CONSULT titles, and much more.
Szczegóły produktu
Mosby
36010
9780323034470
9780323034470

Opis

Rok wydania
2006
Numer wydania
4
Oprawa
miękka foliowana
Liczba stron
248
Wymiary (mm)
191 x 235
Waga (g)
472
  • Introduction to the Kidney

    1 Physiology of Body Fluids

    OBJECTIVES
    PHYSICOCHEMICAL PROPERTIES OF ELECTROLYTE SOLUTIONS
    Molarity and Equivalence
    Osmosis and Osmotic Pressure
    Osmolarity and Osmolality
    Tonicity
    Oncotic Pressure
    Specific Gravity
    VOLUMES OF BODY FLUID COMPARTMENTS
    COMPOSITION OF BODY FLUID COMPARTMENTS
    FLUID EXCHANGE BETWEEN BODY FLUID COMPARTMENTS
    Capillary Fluid Exchange
    Cellular Fluid Exchange
    SUMMARY
    KEY WORDS AND CONCEPTS
    SELF-STUDY PROBLEMS


    2 Structure and Function of the Kidneys

    OBJECTIVES
    STRUCTURE OF THE KIDNEYS
    Gross Anatomy
    Ultrastructure of the Nephron
    Ultrastructure of the Renal Corpuscle
    Ultrastructure of the Juxtaglomerular Apparatus
    Innervation of the Kidneys
    SUMMARY
    KEY WORDS AND CONCEPTS
    SELF-STUDY PROBLEMS


    3 Glomerular Filtration and Renal Blood Flow

    OBJECTIVES
    RENAL CLEARANCE
    Glomerular Filtration Rate
    GLOMERULAR FILTRATION
    Determinants of Ultrafiltrate Composition
    Dynamics of Ultrafiltration
    RENAL BLOOD FLOW
    REGULATION OF RENAL BLOODS FLOW AND GLOMERULAR FILTRATION RATE
    Sympathetic Nerves
    Angiotensin II
    Prostaglandins
    Nitric Oxide
    Endothelin
    Bradykinin
    Adenosine
    Natriuretic Peptides
    ATP
    Glucocorticoids
    Histamine
    Dopamine
    SUMMARY
    KEY WORDS AND CONCEPTS
    SELF-STUDY PROBLEMS


    4 Renal Transport Mechanisms: NaCl and Water Transport Along the Nephron

    OBJECTIVES
    GENERAL PRINCIPLES OF MEMBRANE TRANSPORT
    GENERAL PRINCIPLES OF TRANSEPITHELIAL SOLUTE AND WATER TRANSPORT
    NaCl, SOLUTE, AND WATER REABSORPTION ALONG THE NEPHRON
    Proximal Tubule
    Henles Loop
    Distal Tubule and Collecting Duct
    REGULATION OF NaCL AND WATER REABSORPTION
    SUMMARY
    KEY WORDS AND CONCEPTS
    SELF-STUDY PROBLEMS


    5 Regulation of Body Fluid Osmolality: Regulation of Water Balance

    OBJECTIVES
    ANTIDIURETIC HORMONE
    Osmotic Control of ADH Secretion
    Hemodynamic Control of ADH Secretion
    ADH Actions on the Kidneys
    THIRST
    RENAL MECHANISMS FOR DILUTION AND CONCENTRATION OF THE URINE
    Medullary Interstitium
    Vasa Recta Function
    ASSESSMENT OF RENAL DILUTING AND CONCENTRATING ABILITY
    SUMMARY
    KEY WORDS AND CONCEPTS
    SELF-STUDY PROBLEMS


    6 Regulation of Extracellular Fluid Volume and NaCl Balance

    OBJECTIVES
    CONCEPT OF EFFECTIVE CIRCULATING VOLUME
    VOLUME-SENSING SYSTEMS
    Vascular Low-Pressure Volume Sensors
    Vascular High-Pressure Volume Sensors
    Hepatic Sensors
    Central Nervous System Na+ Sensors
    Volume Sensor Signals
    Renal Sympathetic Nerves
    Renin-Angiotensin-Aldosterone System
    Natriuretic Peptides
    Antidiuretic Hormone
    CONTROL OF RENAL NaCL EXCRETION DURING EUVOLEMIA
    Mechanisms for Maintaining the Delivery of Na+ to the Distal Tubule Constant
    Regulation of Distal Tubule and Collecting Duct Na+ Reabsorption
    CONTROL OF Na+ EXCRETION WITH VOLUME EXPANSION
    CONTROL OF Na+ EXCRETION WITH VOLUME CONTRACTION
    EDEMA
    Alterations in Starling Forces
    The Role of the Kidneys
    SUMMARY
    KEY WORDS AND CONCEPTS
    SELF-STUDY PROBLEMS


    7 Regulation of Potassium Balance

    OBJECTIVES
    OVERVIEW OF K+ HOMEOSTASIS
    REGULATION OF PLASMA [K+]
    Epinephrine
    Insulin
    Aldosterone
    ALTERATIONS OF PLASMA [K+]
    Acid-Base Balance
    Plasma Osmolality
    Cell Lysis
    Exercise
    K+ EXCRETION BY THE KIDNEYS
    CELLULAR MECHANISMS OF K+ SECRETION BY PRINCIPAL CELLS IN THE DISTAL TUBULE AND COLLECTING DUCT
    REGULATION OF K+ SECRETION BY THE DISTAL TUBULE AND COLLECTING DUCT
    Plasma [K+]
    Aldosterone
    Antidiuretic Hormone
    FACTORS THAT PERTURB K+ EXCRETION
    Flow of Tubular Fluid
    Acid-Base Balance
    Glucocorticoids
    SUMMARY
    KEY WORDS AND CONCEPTS
    SELF-STUDY PROBLEMS


    8 Regulation of Acid-Base Balance

    OBJECTIVES
    THE HCO3- BUFFER SYSTEM
    OVERVIEW OF ACID-BASE BALANCE
    NET ACID EXCRETION BY THE KIDNEYS
    HCO3- REABSORPTION ALONG THE NEPHRON
    REGULATION OF H+ SECRETION
    Formation of New HCO3-
    RESPONSE TO ACID-BASE DISORDERS
    Extracellular and Intracellular Buffers
    Respiratory Compensation
    Renal Compensation
    SIMPLE ACID-BASE DISORDERS
    Metabolic Acidosis
    Metabolic Alkalosis
    Respiratory Acidosis
    Respiratory Alkalosis
    ANALYSIS OF ACID-BASE DISORDERS
    SUMMARY
    KEY WORDS AND CONCEPTS
    SELF-STUDY PROBLEMS


    9 Regulation of Calcium and Phosphate Homeostasis

    OBJECTIVES
    CALCIUM
    Overview of Ca++ Homeostasis
    Ca++ Transport along the Nephron
    Regulation of Urinary Ca++ Excretion
    Calcium-Sensing Receptor
    PHOSPHATE
    Overview of Pi Homeostasis
    Pi Transport along the Nephron
    Regulation of Urinary Pi Excretion
    INTEGRATIVE REVIEW OF PARATHYROID HORMONE, CALCITRIOL, AND CALCITONIN ON Ca++ AND PI HOMEOSTASIS
    SUMMARY
    KEY WORDS AND CONCEPTS
    SELF-STUDY PROBLEMS


    10 Physiology of Diuretic Action

    OBJECTIVES
    GENERAL PRINCIPLES OF DIURETIC ACTION
    Sites of Action of Diuretics
    Response of Other Nephron Segments
    Adequate Delivery of Diuretics to Their Site of Action
    Volume of the Extracellular Fluid
    DIURETIC BRAKING PHENOMENON
    MECHANISMS OF ACTION OF DIURETICS
    Osmotic Diuretics
    Carbonic Anhydrase Inhibitors
    Loop Diuretics
    Thiazide Diuretics
    K+-Sparing Diuretics
    Aquaretics
    EFFECT OF DIURETICS ON THE EXCRETION OF WATER AND OTHER SOLUTES
    Solute-Free Water
    K+ Excretion
    HCO3- Excretion
    Ca++ and Pi Excretion
    SUMMARY
    KEY WORDS AND CONCEPTS
    SELF-STUDY PROBLEMS


    Additional Reading

    APPENDIX A Integrative Case Studies

    APPENDIX B Normal Laboratory Values

    APPENDIX C Nephron Function

    APPENDIX D Answers to Self-Study Problems

    APPENDIX E Answers to Integrative Case Studies

    APPENDIX F Review Examination


    Index

Zobacz nowsze wydanie:

Renal Physiology
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