This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of cytology, including gynecologic, nongynecologic exfoliative, fine-needle aspiration, and imaging, it incorporates the most recent clinical, pathologic, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Succinctly written, richly illustrated, and easy to use, Diagnostic Pathology:: Cytopathology, fourth edition, is a one-stop reference for accurate, complete pathology reports-ideal as a day-to-day reference or as a reliable training resource.
SECTION 1: GYNECOLOGIC CYTOPATHOLOGY OVERVIEW Pap Test and Cervical Cancer Screening: History and Reporting Terminology Cytopreparation, Instrumentation, and Automated Screening in Gynecologic Cytology Specimen Adequacy in Cervicovaginal Cytology
BENIGN AND INFECTIOUS CONDITIONS Normal Pap Test Infectious and Other Organisms in Pap Tests Nonneoplastic Findings, Mimics, and Artifacts
SQUAMOUS CELL ABNORMALITIES AND MIMICS Low-Grade Squamous Intraepithelial Lesion and Mimics High-Grade Squamous Intraepithelial Lesion and Mimics Atypical Squamous Cells of Undetermined Significance Atypical Squamous Cells, Cannot Rule Out High-Grade Squamous Intraepithelial Lesion Squamous Cell Carcinoma of Cervix
GLANDULAR CELL ABNORMALITIES Endocervical Adenocarcinoma In Situ, Variants and Mimics Endocervical HPV-Dependent Invasive Adenocarcinoma Endocervical HPV-Independent Gastric Type Adenocarcinoma Endometrial Cancers in Pap Tests Atypical Glandular Cells: Endocervicals, Endometrials, and Glandulars, NOS Endometrial Cells in Pap Test and Glandular Cells Status Post Hysterectomy
EXTRAUTERINE CARCINOMAS AND OTHER MALIGNANCIES OF FEMALE GENITAL TRACT Extrauterine Cancers in Pap Tests Neuroendocrine Carcinoma of Cervix Other Uncommon Malignancies in Pap Tests
MOLECULAR TESTING IN GYNECOLOGIC CYTOLOGY HPV and Other Molecular Testing in Gynecologic Cytology
CEREBROSPINAL FLUID Normal Cerebrospinal Fluid and Contamination by Normal Elements Infectious Meningitis Aseptic and Mollaret Meningitis Subarachnoid Hemorrhage Neurodegenerative Diseases Primary Brain Tumors Leukemia and Lymphoma Metastasis in Cerebrospinal Fluid
PLEURAL, PERITONEAL, PERICARDIAL, AND PELVIC FLUID AND WASHINGS Normal Cellular Components, Reactive Mesothelial Proliferations, and Reporting Terminology Infectious Conditions Autoimmune Diseases Mesothelioma in Effusions and Fine Needle Cytology Malignant Effusion, Carcinomas Metastatic Sarcomas in Effusions and Washings Lymphoid Effusions and Secondary Involvement by Hematopoietic Neoplasms Primary Effusion Lymphoma Endometriosis and Endosalpingiosis Ovarian Neoplasms Immunocytochemistry, Histochemistry, and Other Ancillary Techniques
URINARY CYTOLOGY Normal Urinary Cytology, Specimen Types, and Reporting Terminology Ileal Conduit Specimens Noninfectious Benign Conditions Infectious Benign Conditions Reactive Urothelial Changes Low-Grade Urothelial Lesions Atypical Urothelial Cells High-Grade Urothelial Cancer Squamous Cell Carcinoma of Urinary Bladder Adenocarcinoma of Urinary Bladder Other Malignancies in Urinary Cytology Renal Pelvic Cytology Ancillary Testing, UroVysion, and Others
Overview Role of Fine-Needle Aspiration of Breast, Techniques and Triple Test
Benign Breast Lesions Inflammatory and Granulomatous Conditions Fat Necrosis Nonproliferative and Proliferative Changes in Breast Radial Scar/Complex Sclerosing Lesion Gynecomastia Mucocele-Like Lesion
Benign Neoplasms Fibroadenoma Granular Cell Tumor of Breast Papillary Neoplasms Myofibroblastoma, Mammary
Malignant Neoplasms Ductal Carcinoma and Variants of Invasive Mammary Carcinoma Lobular Carcinoma Phyllodes Tumor Angiosarcoma and Other Sarcomas Lymphomas and Metastatic Tumors
Nipple Discharge Cytology Specimens for Risk Assessment of Breast Cancer
SKIN AND SUBCUTANEOUS CYTOLOGY Cutaneous and Adnexal Cytology Fat Pad Aspiration for Amyloid
SECTION 4: FINE-NEEDLE ASPIRATION, DEEP ORGANS AND TISSUES OVERVIEW Techniques and Modalities of Deep Aspiration Biopsies Techniques and Modalities of Bronchoscopic Aspiration and Small Biopsies Techniques and Modalities of Gastrointestinal Endoscopic Aspiration and Small Biopsies
RESPIRATORY TRACT, INCLUDING LUNG FNAS Specimen Types in Respiratory Cytology and Adequacy Criteria Benign and Reactive Changes Fungal Yeasts and Hyphal Organisms Pneumocystis Pneumonia Parasitic Organisms Viral Infections (Cytomegalovirus, Herpesvirus, and Others) Mycobacteria and Other Bacterial Infections Sarcoidosis and Other Immune-Related Conditions Pulmonary Alveolar Proteinosis and Mimics Miscellaneous Findings, Including Contaminants Adenocarcinoma of Lung Squamous Cell Carcinoma of Lung Small Cell Carcinoma of Lung Large Cell Neuroendocrine Carcinoma of Lung Carcinoid and Atypical Carcinoid of Lung Rare Benign and Low Malignant Potential Tumors Rare Malignant Tumors NUT Carcinoma SMARCA4-Deficient Undifferentiated Tumor Pulmonary Lymphoma Pulmonary Metastasis
MEDIASTINUM
Overview Anatomic Compartments and Constituent Tumors
Nonneoplastic Lesions Mediastinal Cysts and Inflammatory Lesions
Overview Approach to Cytologic/Small Biopsy Diagnosis of Primary Bone Tumors
Neoplasms Chondromas of Bone and Soft Tissue Chondroblastoma Giant Cell Tumor Osteoblastoma Adamantinoma Langerhans Cell Histiocytosis Chordoma Osteosarcoma Chondrosarcoma Ewing Sarcoma Bone Lymphoma Metastatic Tumors of Bone
SOFT TISSUE
Overview Approach to Cytologic/Small Biopsy Diagnosis of Primary Soft Tissue Lesions
SECTION 5: MANAGEMENT AND ANCILLARY TESTING CYTOPREPARATORY AND QUALITY MANAGEMENT Cytopreparatory Techniques and Instrumentation in Nongynecologic Cytology Quality Improvement and Laboratory Management for Cytopathology