Developments in and current clinical uses of image-guided treatments and radiotherapies for ear, skull base, and brain disorders are discussed in this issue of Otolaryngology. Contents:: Neurotology Development through the Years; Imaging of the Temporal Bone and Skull Base; Intracranial Pressure Concerns in Lateral Skull Base Surgery; Endolymphatic Sac Tumors; Petrous Apex Lesions and Approaches; Guiding Patients through the Decision Process for Treatment of Vestibular Schwannoma; LINAC Stereotactic Radiation Therapy for Acoustic Neuroma; Sterotactic Radiation Therapy for Lateral Skull Base Lesions; Surgical Approaches for Acoustic Neuroma; Image-Guided Technique in Neurotology; Glomus Tumors of the Temporal Bone; Management of Complications in Neurotology; Contemporary Management of Sudden Sensorineural Loss.