In this issue of Oral and Maxillofacial Surgery Clinics, guest editors Drs. Neha Sharma and Florian M. Thieringer bring their considerable expertise to the topic of Advancements in Personalized Digital Oral Surgery. Top experts in the field discuss technologies such as CAD/CAM, 3D printing, robotic surgery, virtual reality, and artificial intelligence, as well as clinical areas such as the temporomandibular joint, the orbit, implants, mandibular and maxillary reconstruction, and orthognathics.