The most comprehensive text and definitive guide for nearly 30 years about optical coherence tomography (OCT) imaging in ophthalmology, Optical Coherence Tomography of Ocular Diseases, Fourth Edition covers a range of subjects, from principles and operation techniques to clinical interpretation and the latest innovations in OCT.
Written by the pioneers of OCT technologies and the world-renowned OCT researchers Drs. Joel S. Schuman, James G. Fujimoto, Jay S. Duker, Hiroshi Ishikawa, and Gadi Wollstein, Optical Coherence Tomography of Ocular Diseases, Fourth Edition is an essential text for imaging technology.
OCT now occupies a dominant role as a diagnostic tool for retinal conditions and glaucoma. At the same time, the technology continues to show potential for emerging clinical and research applications across all the ophthalmological subspecialties. To reflect these rapid advances, this new edition of Optical Coherence Tomography of Ocular Diseases features a complete and thorough revision of the existing text as well as the addition of cutting-edge content to bring this classic resource completely up to date.
New content in the Fourth Edition includes:: • OCT angiography • Swept-source OCT • OCT in multimodal imaging • Clinical utility of OCT in glaucoma prediction and progression detection • OCT for neuro-ophthalmology
Optical Coherence Tomography of Ocular Diseases, Fourth Edition is the one and only book needed by practitioners who use OCT for clinical eye care.
Dedication About the Editors About the Assistant Editor Contributing Authors Preface
Section I Principles of Operation and Interpretation
Chapter 1 Introduction to Optical Coherence Tomography James G. Fujimoto, PhD; Eric M. Moult, BEng; David Huang, MD, PhD; Joel S. Schuman, MD; Jay S. Duker, MD; Carmen A. Puliafito, MD, MBA; and Eric Swanson, MS Introduction The Early Development of Optical Coherence Tomography Optical Coherence Tomography High-Speed Spectral/Fourier-Domain Optical Coherence Tomography En Face Optical Coherence Tomography Imaging Ultrahigh-Speed Swept-Source/Fourier-Domain Optical Coherence Tomography Optical Coherence Tomography Angiography Conclusion
Chapter 2 Interpretation of the Optical Coherence Tomography Image Hiroshi Ishikawa, MD; Gadi Wollstein, MD; Katie A. Lucy, BS; Lindsey S. Folio, MS, MBA; Jessica E. Nevins, MS; James G. Fujimoto, PhD; Joel S. Schuman, MD; and Carmen A. Puliafito, MD, MBA Introduction Interpreting Optical Coherence Tomography Images of the Normal Retina Interpreting Optical Coherence Tomography Images of the Normal Anterior Eye Optical Coherence Tomography Scanning and Imaging Protocols Quantitative Measurements of Retinal Morphology Quality, Artifacts, and Errors in Optical Coherence Tomography Images Conclusion
Section II Optical Coherence Tomography in Retinal Diseases
Chapter 3 Vitreoretinal Interface Disorders Shilpa J. Desai, MD; Heeral R. Shah, MD; Elias C. Mavrofrides, MD; Adam H. Rogers, MD; Steven N. Truong, MD; Carmen A. Puliafito, MD, MBA; James G. Fujimoto, PhD; and Jay S. Duker, MD Idiopathic Epiretinal Membrane Vitreomacular Traction Syndrome Idiopathic Macular Hole
Chapter 4 Retinal Vascular Diseases Vanessa Cruz-Villegas, MD; Heeral R. Shah, MD; James G. Fujimoto, PhD; Jay S. Duker, MD; Carmen A. Puliafito, MD, MBA; and Shilpa J. Desai, MD Branch Retinal Artery Occlusion Central Retinal Artery Occlusion Branch Retinal Vein Occlusion Central Retinal Vein Occlusion Bilateral Idiopathic Juxtafoveal Retinal Telangiectasis Retinal Arterial Macroaneurysm
Chapter 5 Diabetic Retinopathy James Lin, MD; Jin Yang, MD, PhD; Harry W. Flynn Jr, MD
Chapter 6 Central Serous Chorioretinopathy Shilpa J. Desai, MD; Heeral R. Shah, MD; Elias C. Mavrofrides, MD; Carmen A. Puliafito, MD, MBA; James G. Fujimoto, PhD; and Jay S. Duker, MD Typical Central Serous Chorioretinopathy Chronic Central Serous Chorioretinopathy Bullous Central Serous Chorioretinopathy Laser Treatment for Central Serous Chorioretinopathy Central Serous Chorioretinopathy RTVue-100 Photodynamic Therapy Treatment for Central Serous Chorioretinopathy
Chapter 7 Age-Related Macular Degeneration Shilpa J. Desai, MD; Heeral R. Shah, MD; Elias C. Mavrofrides, MD; Natalia Villate, MD; Carmen A. Puliafito, MD, MBA; and Jay S. Duker, MD Drusen Adult Vitelliform Dystrophy Geographic Atrophy Occult Choroidal Neovascularization Vascularized Pigment Epithelial Detachment Retinal Angiomatous Proliferation Retinal Pigment Epithelium Tear Subretinal Hemorrhage Disciform Scar
Chapter 8 Pathologic Myopia Heeral R. Shah, MD and Shilpa J. Desai, MD Pathologic Myopia Angioid Streaks Myopic Choroidal Neovascularization Myopic Macular Hole Myopic Schisis Rhegmatogenous Retinal Detachment
Chapter 9 Chorioretinal Inflammatory and Infectious Diseases Shilpa J. Desai, MD; Heeral R. Shah, MD; Natalia Villate, MD; Elias C. Mavrofrides, MD; Janet Davis, MD; Jay S. Duker, MD; and Carmen A. Puliafito, MD, MBA
Chapter 10 Retinal Dystrophies Vanessa Cruz-Villegas, MD; Heeral R. Shah, MD; Jay S. Duker, MD; Shilpa J. Desai, MD; and Carmen A. Puliafito, MD, MBA Retinitis Pigmentosa Stargardt Disease Best Disease Adult-Onset Foveomacular Vitelliform Dystrophy
Chapter 11 Miscellaneous Retinal Diseases Shilpa J. Desai, MD; Heeral R. Shah, MD; Elias C. Mavrofrides, MD; Vanessa Cruz-Villegas, MD; Carmen A. Puliafito, MD, MBA; and Jay S. Duker, MD Cystoid Macular Edema Posterior Segment Trauma Optic Nerve Pit
Section III Optical Coherence Tomography in Glaucoma, Neuro-Ophthalmology, and the Anterior Segment
Chapter 12 Clinical Utility of Optical Coherence Tomography in Glaucoma Gadi Wollstein, MD; Maria de los Angeles Ramos Cadena, MD; Katie A. Lucy, BS; Lindsey S. Folio, MS, MBA; Jessica E. Nevins, MS; and Joel S. Schuman, MD Normal Preperimetric/Early Glaucoma Moderate Glaucoma Advanced Glaucoma Utility of Imaging in Longitudinal Glaucoma Assessment
Chapter 13 Optical Coherence Tomography for Neuro-Ophthalmology Rithambara Ramachandran, MD; Carlos Mendoza-Santiesteban, MD; Matthew D. Lazzara, MD; Thomas R. Hedges III, MD; Steven Galetta, MD; Laura Balcer, MD, MSCE; and Rachel Nolan-Kenney, MPhil Proving Maculopathy That May Mimic Optic Neuropathy Optic Neuropathy in the Presence of Retinopathy Functional Loss of Vision Optic Nerve Swelling Compressive Optic Neuropathy Toxic, Hereditary, and Nutritional Optic Neuropathy Optic Neuritis Multiple Sclerosis, Neuromyelitis Optica, and Anti–Myelin Oligodendrocyte Glycoprotein Syndromes Microcystic Macular Edema Neurodegenerative Diseases Optical Coherence Tomography Angiography Conclusion
Chapter 14 Anterior Segment Optical Coherence Tomography Yuli Yang, MD, PhD; Yan Li, PhD; and David Huang, MD, PhD Introduction Optical Coherence Tomography Devices Interpretation of Corneal Images Angle Assessment Refractive Surgery Small Incision Lenticule Extraction Corneal Pathologies and Surgeries
Section IV Appendix
Appendix Optical Coherence Tomography Scanning and Image-Processing Protocols Hiroshi Ishikawa, MD; Gadi Wollstein, MD; Lindsey S. Folio, MS, MBA; Jessica E. Nevins, MS; James G. Fujimoto, PhD; and Joel S. Schuman, MD Line and Radial Scan Protocols Circle Scan Protocols Compound Radial and Concentric Circles Scan Protocols Three-Dimensional Cube Raster Scan Protocols Eye Motion Tracking Image-Processing Protocols Repeated Scan (Image) Averaging Segmentation C-Mode Circumpapillary Retinal Thickness and Retinal Layer Thickness Map Optic Nerve Head Macula Progression Analysis Anterior Segment Optical Coherence Tomography Scan Protocols
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