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Tumor Suppressors

Tumor Suppressors

9781617619861
592,14 zł
532,92 zł Zniżka 59,22 zł Brutto
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Opis
A tumour suppresser gene, or anti-oncogene, is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its function, the cell can progress to cancer, usually in combination with other genetic changes. This book presents topical research data in the study of tumour suppressers, including Rab GTPases as potential tumour suppressers; the regulation of neutrophil function by tumour suppresser PTEN; the role of BRIT1/MCPH1 in genome maintenance and tumour suppression; epigenetic silencing of tumour suppressers; and the relationship between MicroRNA and tumour suppressers.
Szczegóły produktu
73616
9781617619861
9781617619861

Opis

Rok wydania
2011
Numer wydania
1
Oprawa
twarda
Liczba stron
280
Wymiary (mm)
260.00 x 180.00
Waga (g)
718
  • Preface; Aflatoxin B1 & Acetaldehyde Mutational Patterns in the Tumour Suppressor Gene TP53:: Experimental Fingerprints using a Functional Assay & Relevance to Human Cancer Aetiology; Curative Therapy for Terminal Cancer?; Breast Cancer Screening by Methylation Analysis of Tumor Suppressor Genes in Breast Fluid; Rab GTPases as Potential Tumor Suppressors; Regulation of Neutrophil Function by Tumor Suppressor PTEN; Wnt Pathway-Independent Activities of the APC Tumor Suppressor; Emerging Roles of BRIT1/MCPH1 in Genome Maintenance & Tumor Suppression; The Role of Histone Deacetylase (HDAC) & EZH2 in Oncogenesis:: Epigenetic Silencing of Tumor Suppressors; Functions of Kank1 & Carcinogenesis; The Relationship between MicroRNA & Tumor Suppressors; Biomarkers for Radiosensitivity & Radiosensitization Targets in Prostate Cancer; Molecular Functions of the p53 Tumor Suppressor in the Apoptotic Response to DNA Damage; How Does Tumor Suppressor FHIT Modulate Oxidative Stress & DNA Damage Checkpoints in Early Cancer?; Role of the Tumor Suppressor PDCD4 in the Differentiation of the Skin; Index.
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