In this issue of Neurosurgery Clinics, guest editors Drs. George I. Jallo and Nir Shimony bring their considerable expertise to the topic of Intramedullary Spinal Cord Tumors. Top experts address the history of spinal cord tumor surgery, management of adult and pediatric spinal cord tumors, and vascular lesions of the spinal cord, as well as pathological diagnosis of intramedullary spinal cord tumors (gliomas and ependymomas) with new molecular understanding for these tumors, and more.