With advances in medicine and medical innovation, the face of neurosurgery has changed dramatically. A new era of surgeons value the need to undertake research in everyday practice and actively participate in the clinic and laboratory in order to improve patient prognosis. Highlighting the principles of basic neuroscience and its application to neurosurgical disease, this book breaks down neurological conditions into current academic themes and advances. The book is split into two sections, with the first covering basic and computational neuroscience including neuroanatomy, neurophysiology, and the growing use of artificial intelligence. The second section concentrates on specific conditions, such as gliomas, degenerative cervical myelopathy and peripheral nerve injury. Outlining the pathophysiological underpinnings of neurosurgical conditions and the key investigative tools used to study disease burden, this book will be an invaluable source for the academic neurosurgeon undertaking basic and translational research.
Section 1. Basic and computational neuroscience: 1. Neuroanatomy Farhana Akter, Charles Reilly, Christophe Dupre, and Shifa Hossain; 2. Cerebral autoregulation Xingping Qin, Parisa Nikrouz and Farhana Akter; 3. Neuroimmune interactions Allison Chang; 4. Anatomy and physiology of the neuron Oluwatobi Ariyo and Farhana Akter; 5. Synaptic transmission Katrina Hon and Nigel Emptage; 6. Sensory pathways Rachel Chau, Megan Chau and Farhana Akter; 7. Somatosensory and somatic motor systems Maria Kaltchenko and Farhana Akter; 8. Neuron models Kumaresh Krishnan; 9. An introduction to artificial intelligence and machine learning Shun Yao, Ye Wu and Farhana Akter; 10. Artificial intelligence in neuroscience Will Xiao, Mengmi Zhang and Gabriel Kreiman; 11. Probability and statistics Zachary T. Miller; Section 2. Clinical neurosurgical diseases; 12. Glioma David M. Ashley and Justin T. Low; 13. Brain metastases: molecules to medicine Ethan S. Srinivasan, Vadim Tsvankin, Eric W. Sankey, Matthew M. Grabowski, Pakawat Chongsathidkiet and Peter E. Fecci; 14. Benign adult brain tumors and pediatric brain tumors Shun Yao, Umar Raza and Farhana Akter; 15. Biomechanics of the spine Gaetano De Biase and Kingsley Abode-Iyamah; 16. Degenerative cervical myelopathy Timothy J. Florence, Joel S. Beckett and Langston T. Holly; 17. Spondylolisthesis Yike Jin, Ann Liu, Ravi Medikonda and Timothy F. Witham; 18. Radiculopathy Yingda Li and Michael Y Wang; 19. Spinal tumors Ziev B. Moses, Matthew Trawczynski and John E OToole; 20. Acute spinal cord injury and spinal trauma Dominique M. O. Higgins, Pavan S. Upadhyayula, Michael Argenziano and Paul McCormick; 21. Traumatic brain injury Kristin A. Keith and Jason H. Huang; 22. Vascular neurosurgery Karol P. Budohoski and Adib A. Abla; 23. Pediatric vascular malformations Alaa Montaser and Edward R. Smith; 24. Craniofacial neurosurgery John T. Smetona and John A. Persing; 25. Hydrocephalus Benjamin C. Reeves, Jason K. Karimy, Phan Q. Duy and Kristopher T. Kahle; 26. Peripheral nerve injury response mechanisms Andrew S. Jack and Line Jacques; 27. Clinical peripheral nerve injury models Andrew S. Jack, Charlotte J. Huie and Line Jacques; 28. The neuroscience of functional neurosurgery Joseph S. Bell, TJ Florence, Maya Harary, Maxwell D. Melin, Hiro Sparks and Nader Pouratian; 29. Neuroradiology: focused ultrasound in neurosurgery Massimiliano Del Bene, Roberto Eleopra, Francesco Prada and Francesco DiMeco; 30. Magnetic resonance imaging in neurosurgery David J. Segar, Jasmine A. Thum, Dhiego Bastos and Alexandra J. Golby; 31. Brain mapping Anthony T. Lee, Cecilia Dalle Ore and Shawn L. Hervey-Jumper.
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