Autonomic surgery is an important and expanding field within contemporary clinical practice. Surgical therapies influencing the autonomic nervous system have historically entailed disabling various components of its network by injurious methods. More sophisticated techniques have now emerged to allow modulation of neural function by electrical implants or by preservative surgery. This has fuelled the expansion in this field as safer therapies with greater scope for patient benefithave become available. As the potential for precise neural manipulation has advanced, so has the number and diversity of diseases which have become amenable to such therapies. This book reviews the basic science underpinning the autonomic control of various body systems and the state-of-the-art clinical applications by which these systems are surgically modulated in patients today. Clinical chapters include details of the procedure, operative considerations, outcomes, adverse effect profile, post-operative management of such patients and reflections on personal experience. Autonomic surgery can be applied to a wide variety of diseases affecting large numbers of thepopulation such as angina pectoris, hypertension, orthostatic hypotension, sexual dysfunction, regional pain syndromes, headache and epilepsy.
Neural Control of the Heart and Cardiovascular System; Baroreceptor Activation Therapy: A Surgical Approach to the Treatment of Hypertension; Deep Brain Stimulation and Blood Pressure Disorders; Lateral Medullary Decompression for Essential Hypertension; Device-based Approaches to Target Renal Sympathetic Nerves for Hypertension; Evolution and Developments in Autonomic Control of the Heart. I: the Neurocardiac Axis; Evolution and Developments in Autonomic Control of the Heart. II: Therapeutical Interventions; Periarterial Sympathectomy in the Treatment of Upper Extremity Peripheral Vascular Disease; Spinal Cord Stimulation for Complex Regional Pain Syndrome. I: Mechanisms; Spinal Cord Stimulation for Complex Regional Pain Syndrome. II: Clinical Applications; Trigeminal Autonomic Cephalalgias. I: Peripheral Neuromodulation (Occipital Nerve and Sphenopalatine Ganglion Stimulation); Trigeminal Autonomic Cephalalgias. II: Deep Brain Stimulation of the Posterior Hypothalamus for Chronic Cluster Headache; The Central Nervous System in Control of Continence and Sexual Functions; Pudendal Nerve Stimulation; Sacral Nerve Stimulation for Lower Urinary Tract Dysfunction; Neuromodulation for Faecal Incontinence and Constipation; Gastric Stimulation for Obesity and Gastroparesis; Hyperhidrosis: Pathophysiology and Available Therapies; Vagus Nerve Stimulation in the Treatment of Epilepsy. I: History, Vagus Nerve Physiology, and Putative Mechanisms; Vagus Nerve Stimulation in the Treatment of Epilepsy. II: Procedure, Evidence, and Adverse Events;
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