MYOLOGY,3/E

SCIENTIFIC BASIS

Development, Differentiation and Diversity

1 The Embryonic Origin of Muscle
2 Morphogenesis of skeletal muscle fibers
3 Satellite and stem cells; muscle regeneration
4 The Diversity of Muscle Fibers and its Origin
5 Physiology of Motor Units and their Control
6 The extraocular muscles, Muscle contraction
7 The Structure of Contractile Filaments
8 The Structure of Vertebrate Muscle Myosin
9 The Cross Bridge Cycle and the Energetics of Muscle Contraction

The control of muscle fiber activity

10 Ionic Channels and their Function in Muscle Activity
11 The Sarcoplasmic Reticulum and the Transverse Tubules
12 Excitation-Contraction Coupling in Skeletal Muscle
13 Activation of the Contractile Mechanism by Calcium
14 The Proteins of the Sarcoplasmic Reticulum

Neuromuscular transmission

Muscle as a tissue

19 The Subcortical Cytoskeleton and the Plasma Membrane
20 The Extracellular Matrix
21 The Muscle Spindle
22 The Microcirculation of Muscle
23 Protein and Amino Acid Metabolism in Muscle
24 Lysosomal Metabolism and its Relevance to Skeletal Muscle

GENERAL APPROACHES TO NEUROMUSCULAR DISEASES

25 The clinical examination
26 Electrodiagnosis of Muscle disorders
27 Muscle Imaging
28 Noninvasive evaluation of metabolic myopathies
29 The Muscle Biopsy
30 Basic Reactions of Muscle
31 Ultrastructural changes in diseased muscle
32 Immune Mechanisms in Muscle Diseases
33 The Tools of Molecular Genetics And Their Application to the Study Of Muscle Diseases

DISEASES OF MUSCLE

Muscular Dystrophies

34 Dystrophinopathies
35 Emery-Dreifuss Muscular Dystrophy
36 Myotonic Dystrophy
37 Limb Girdle Dystrophies
38 Facioscapulohumeral Dystrophy and Scapuloperoneal Syndrome
39 Bethlem Myopathy
40 Oculopharyngeal Muscular Dystrophy
41 X-Linked Vacuolar Myopathy
42 Distal Muscular Dystrophies
43 Myofibrillar Myopathies
44 Congenital Muscular Dystrophies
45 Cardiomyopathies Associated with Muscular Dystrophies

Altered Excitability of the Cell Membrane

46 Nondystrophic Channelopathies:: Myotonias and Per Paralyses
47 Neuromyotonia

Inflammatory Myopathies

48 Polymyositis and Dermatomyositis Syndromes
49 Sporadic Inclusion Body Myositis
50 Inclusion Body Myopathy
51 Virus Related Muscle Diseases
52 Parasitic Myositis
53 Other Inflammatory Myopathies

Congenital Myopathies

54 Congenital Myopathies

Metabolic Disorders Affecting Muscle

55 Nonlysosomal Glycogenoses (and review of carbohydrate metabolism)
56 Acid Maltase Deficiency
57 Disorders of Lipid Metabolism (and review of lipid metabolism)
58 Mitochondrial Diseases
59 Malignant Hyperthermia
60 Myoglobinura
61 Myopathies due to Drugs, Toxins, and Nutritional Deficiency
62 Endocrine Myopathies
63 Muscle Pain, Cramps, and Fatigue

Disturbances of Neuromuscular Transmission

64 Autoimmune Myasthenia Gravis
65 Lambert-Eaton Myasthenic Syndrome
66 Congenital Myasthenic Syndromes

Neural Diseases

67 Motor Neuron Diseases in Children
68 Motor Neuron Diseases in Adults
69 Disease of Peripheral Nerves
70 Congenital Deformities