Oxford Textbook of Clinical Nephrology

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Wydawca: OUP Oxford

ISBN: 9780199592548

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Opis

This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasisthroughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrologys position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a years access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.

Szczegóły produktu

Wydawca OUP Oxford

Indeks 85052

EAN13 9780199592548

ISBN 9780199592548

Opis

Rok wydania: 2015
Numer wydania: 4
Liczba stron: 3296
Wymiary (mm): 219 x 276
Waga (g): 8912

VOLUME 1; Part 1:: Assessment of the patient with renal disease; Epidemiology of kidney disease; Clinical assessment of the patient with renal disease; Presentations of renal disease; Kidney disease focused history taking; Kidney disease focused features on examination; Urinalysis; Assessment of renal function; Tubular function; Renal radiology:: overview; Ionising radiation and radiation protection; Plain radiography, excretion radiography, and contrast radiography; Intervention; Ultrasound; Computed tomography; Magnetic Resonance Imaging; Radioisotopes in diagnostic imaging in nephrology; Immunological investigation of the patient with renal disease; The renal biopsy; Clinical trials- how and why in nephrology; Part 2:: The patient with fluid, electrolyte, and renal tubular disorders; An overview of tubular function; Sodium transport and balance:: A key role for the distal nephron; Water homeostasis; Potassium homeostasis; Renal acid-base homeostasis; Phosphate homeostasis; Calcium homeostasis; Magnesium homeostasis; Approach to the patient with hyponatraemia; Approach to the patient with hypernatraemia; Approach to the patient with oedema; Approach to the patient with salt-wasting; Approach to the patient with polyuria; Clinical use of diuretics; Approach to the patient with hypo-/hyperkalaemia; Approach to the patient with metabolic acidosis or alkalosis; Approach to the patient with renal tubular acidosis; Approach to the patient with hypercalcaemia; Approach to the patient with hypocalcaemia; Approach to the patient with hypo-/hyperphosphataemia; Approach to the patient with hypomagnesaemia; Approach to the patient with renal Fanconi syndrome, glycosuria or aminoaciduria; Part 3:: The patient with glomerular disease; The glomerulus and the concept of glomerulonephritis; The renal glomerulus - the structural basis of ultrafiltration; Function of the normal glomerulus; Mechanisms of glomerular injury:: overview; The patient with haematuria; Loin pain haematuria syndrome; Nutcracker syndrome and phenomenon; Exercise-related pseudonephritis; Proteinuria; Postural proteinuria (Benign orthostatic proteinuria); Nephrotic syndrome; Pathophysiology of oedema in nephrotic syndrome; Idiopathic nephrotic syndrome:: overview; Minimal change disease:: clinical features and diagnosis; Minimal change disease:: treatment and outcome; Primary focal segmental glomerulosclerosis (FSGS):: Clinical features and diagnosis; Primary focal segmental glomerulosclerosis (FSGS):: Treatment and outcome; Pathogenesis of proteinuria in minimal change disease and FSGS; Membranous glomerulonephritis:: overview; Membranous glomerulonephritis:: clinical features and diagnosis; Membranous glomerulonephritis:: treatment and outcome; Secondary membranous glomerulonephritis; Membranous glomerulonephritis:: pathogenesis; Immunoglobulin A nephropathy:: overview; Immunoglobulin A nephropathy:: clinical features; Immunoglobulin A nephropathy:: diagnosis; Immunoglobulin A nephropathy:: treatment and outcome; Immunoglobulin A nephropathy:: pathogenesis; Crescentic (rapidly progressive) glomerulonephritis; Anti-glomerular basement membrane disease:: overview; Anti-glomerular basement membrane disease:: clinical features and diagnosis; Anti-glomerular basement membrane disease:: treatment and outcome; Antiglomerular basement membrane disease:: pathogenesis; Alport post-transplant antiglomerular basement membrane disease; Post-infectious glomerulonephritis:: overview; Post streptococcal glomerulonephritis; Immunoglobulin A dominant post-infectious glomerulonephritis; Glomerulonephritis associated with endocarditis, deep-seated infections and shunt nephritis; Membranoproliferative glomerulonephritis and C3 glomerulopathy; Fibrillary and immunotactoid glomerulopathy; Drug induced and toxic glomerulopathies; Part 4:: The patient with interstitial disease; Acute tubulointerstitial nephritis:: overview; Drug-induced acute tubulointerstitial nephritis; Other toxic acute tubulointerstitial nephritis; Chronic tubulointerstitial nephritis:: overview; Drug-induced chronic tubulointerstitial nephritis; Heavy metals-induced tubulointerstitial nephritis; Aristolochic acid nephropathy caused by ingestion of herbal medicinal products; Balkan endemic nephropathy; Radiation nephropathy; Urate nephropathy; Immune-mediated tubulointerstitial nephritis; Part 5:: The patient with reduced renal function; Chronic kidney disease:: definition, classification, and approach to management; Chronic kidney disease in the developed world; Chronic kidney disease in developing countries; Chronic kidney disease long-term outcomes:: progression, death, cardiovascular disease, infections, and hospitalizations; Cardiovascular disease and chronic kidney disease:: overview; Recommendations for management of high renal risk chronic kidney disease; Hypertension as a cause of chronic kidney disease:: what is the evidence?; Diet and the progression of chronic kidney disease; Lipid disorders of patients with chronic kidney disease; Smoking in chronic kidney disease; Analytical aspects of measurements and laboratory values in chronic and acute kidney disease; Effect of lifestyle modifications on patients with chronic kidney disease; Malnutrition, obesity, and undernutrition in chronic kidney disease; Left ventricular hypertrophy in chronic kidney disease; Sudden cardiac death in chronic kidney disease; Epidemiology of calcium, phosphate and PTH disturbances in chronic kidney disease; The role of inflammation in chronic kidney disease; Vascular stiffness in chronic disease - pathophysiology and implications; Oxidative stress and its implications in chronic disease; Abnormal endothelial vasomotor and secretory function; Endothelins and their antagonists in chronic kidney disease; Chronic kidney disease-mineral and bone disorder:: overview; Imaging for detection of vascular disease in chronic kidney disease patients; Pathophysiology of chronic kidney disease - mineral and bone disorder; Management of chronic kidney disease - mineral and bone disorder; Fibroblast growth factor 23, klotho, and phosphorus metabolism in chronic kidney disease; Vascular calcification; Fractures in patients with chronic kidney disease; Spectrum of bone pathologies in chronic kidney disease; Clinical aspects and overview of renal anaemia; Erythropoiesis-stimulating agents in chronic kidney disease; Iron metabolism in chronic kidney disease; Iron management in renal anaemia; Pleoitropic effects of Vitamin D; Immunity; The liver and chronic kidney disease; Gastroenterology and renal medicine; Cutaneous manifestations of end-stage renal disease (ESRD); The patient with reduced renal function:: endocrinology; Sexual dysfunction; Health related quality of life and the patient with chronic kidney disease; Coagulopathies in chronic kidney disease; Mechanisms of progression of chronic kidney disese- overview; Proteinuria as a direct cause of progression; Nephron numbers and hyperfiltration as drivers of progression; Podocyte loss as a common pathway to chronic kidney disease; Disordered scarring and failure of repair; Modality selection for renal replacement therapy; Patient education and involvement in pre-dialysis management; Preparation for renal replacement therapy; Choices and considerations for in-centre versus home based renal replacement therapy; Conservative care in advanced chronic kidney disease; Palliative care in end stage renal disease; Patient selection when resources are limited; Acidosis in chronic kidney disease; VOLUME 2; Part 6:: The patient with another primary diagnosis; The patient with diabetes mellitus; Kidney involvement in plasma cell dyscrasias; The patient with cryoglobulinaemia; The patient with amyloidosis; The patient with myeloma; Light chain deposition disease; Other consequences from monoclonal immunoglobulins/fragments:: Membranoproliferative Glomerulonephritis and Acquired Fanconi Syndrome; The patient with sarcoidosis; The patient with vasculitis- overview; The patient with vasculitis:: pathogenesis; The patient with vasculitis:: clinical aspects; The patient with vasculitis:: treatment and outcome; The patient with systemic lupus erythematosus:: overview and pathogenesis; The patient with systemic lupus erythematosus:: clinical features, investigations, and diagnosis; The patient with systemic lupus erythematosus:: treatment and outcome; The patient with antiphospholipid syndrome with or without lupus; The patient with scleroderma-systemic sclerosis; The patient with rheumatoid arthritis, mixed connective tissue disease, polymyositis, Sjögren syndrome, or overlap syndrome; The patient with sickle cell anemia; The obese patient (metabolic syndrome); The patient with hepatorenal syndrome; Kidney/ear syndromes; Kidney/eye syndromes; The patient with renal cell cancer; The patient with Wilms tumour; The patient with haemolytic uraemic syndrome/thrombotic thrombocytopenic purpura; Part 7:: The patient with urinary tract infection; Urinary tract infection in the adult:: overview; Infection of the lower urinary tract; Upper urinary tract infection; Complicated urinary tract infection; Urinary tract infection in a patient with a kidney transplant; Urinary tract infection in infancy and childhood; Schistosomiasis:: the parasite and the host; Schistosomiasis:: clinical impact; Part 8:: The patient with infections causing renal disease; Malaria; Leishmaniasis and trypanosomiasis; Hepatitis B; Hepatitis C; HIV and renal disease; Hantaviral infections; Dengue and other viral haemorrhagic fevers; Yellow fever, severe acute respiratory syndrome virus, and H1N1 influenza infections; Leptospirosis; Syphilis; Rickettsiosis; Schistosomiasis; Nematode infections; Mycobacterial infections:: tuberculosis; Mycobacterial infections:: leprosy and environmental mycobacteria; Renal involvement in other infections; Part 9:: The patient with urinary stone disease; Epidemiology of nephrolithiasis; Approach to the patient with kidney stones; Calcium stones; Uric acid stones; Cystine stones; Cell biology of nephrocalcinosis/nephrolithiasis; Medical management of nephrocalcinosis and nephrolithiasis; Imaging and interventional treatment:: urolithiasis from the surgeon s point of view; Part 10:: The patient with hypertension; The structure and function of renal blood vessels; Regulation of vasomotor tone in the afferent and efferent arterioles; Tubuloglomerular feedback and autoregulation of renal blood flow and glomerular filtration rate; The kidney and control of blood pressure; The effect of hypertension on renal vasculature and structure; Ischaemic nephropathy; Renal artery stenosis:: clinical features and diagnosis; Renal artery stenosis:: diagnosis; Renal artery stenosis:: management and outcome; Malignant hypertension; Resistant hypertension; The hypertensive child; Treatment of hypertension in children; Part 11:: The patient with acute kidney injury (and critical care nephrology); Definitions, classification, epidemiology, and risk factors of acute kidney injury; Pathophysiology of acute kidney injury; Clinical approach to the patient with acute kidney injury:: diagnosis and differential diagnosis; The role of novel biomarkers in acute kidney injury; Prevention of acute kidney injury:: overview; Prevention of acute kidney injury:: non-pharmacological strategies; Prevention of acute kidney injury:: pharmacological strategies; Prevention of acute kidney injury:: drug- and nephrotoxin-induced acute kidney injury; Non-dialytic management of the patient with acute kidney injury; Fluid overload; Electrolyte and acid-base disorders; Coagulation disturbances; Renal replacement therapy in the patient with acute kidney injury:: overview; Intermittent acute renal replacement therapy; Continuous renal replacement therapy; Peritoneal dialysis in acute kidney injury; Scoring systems in acute kidney injury patients; Short and long-term overall outcome and renal prognosis of AKI; Overall and renal prognosis of AKI; Acute kidney injury in children; Acute kidney injury in the elderly; Acute kidney injury in the tropics; Acute kidney injury and hantavirus disease; Community-acquired pneumonia and acute kidney injury; Acute kidney injury in severe sepsis; Cardiovascular surgery and acute kidney injury; Contrast-induced acute kidney injury; Renal failure in cirrhosis:: pathogenesis, diagnosis, and treatment; Acute kidney injury in heart failure; Acute kidney injury in pulmonary diseases; Acute kidney injury in pregnancy; Acute kidney injury in the cancer patient; Acute kidney injury in polytrauma and rhabdomyolysis; Acute kidney injury in patients with severe burn injury; VOLUME 3; Part 12:: The patient on dialysis; Uraemic toxins:: overview; Haemodialysis:: overview; Haemodialysis:: vascular access; Haemodialysis:: principles; Haemodialysis:: prescription and assessment of adequacy; Hemodialysis:: acute complications; Haemofiltration and haemodiafiltration; Dialysis withdrawal and palliative care; Frequent haemodialysis; Peritoneal dialysis:: overview; Peritoneal dialysis:: principles and peritoneal physiology; Peritoneal dialysis:: adequacy and prescription management; Peritoneal dialysis:: non-infectious complications; Overview of dialysis patient management and future directions; Cardiovascular complications in end-stage renal disease patients:: pathophysiological aspects; Bacterial and fungal infections in patients on haemodialysis; Bacterial and fungal infections in patients on peritoneal dialysis; Virus infections in patients on dialysis; Cognitive function, depression, and psychosocial adaptation; Volume assessment and management in dialysis; Nutritional screening and nutritional management in dialysis patients; Part 13:: The transplant patient; The evolution of kidney transplantation; Pre-transplant assessment of the recipient; Organ donation; Donor and recipient kidney transplantation surgery; Immunology, sensitization, and histocompatibility; Immediate post-transplant care and surgical complications; Immunosuppression, drugs, and protocols; Renal transplant imaging; Rejection; Infection:: prophylaxis, diagnosis, and management; Cardiovascular disease:: prophylaxis, diagnosis, and management; Chronic allograft dysfunction; Cancer after kidney transplantation; Metabolic bone disease:: prophylaxis, diagnosis, and management; Recurrent renal disease:: prophylaxis, diagnosis, and management; Paediatric renal transplantation; Part 14:: Renal disease at different stages of life; Growth and development; The adolescent with renal disease:: transition to adult services; Contraception in patients with kidney disease; Pregnancy and renal physiology; Pregnancy in patients with chronic kidney disease and on dialysis; Pre-eclampsia and related disorders; Acute renal disease in pregnancy; Specific renal conditions in pregnancy; Pregnancy after renal transplantation; The kidney in ageing:: biology, anatomy, physiology, and clinical relevance; Part 15:: The patient with genetic renal disease; Ethical aspects of genetic testing; Antenatal diagnosis and pre-implantation genetic testing; The molecular basis of ciliopathies and cyst formation; The adult with renal cysts; The child with renal cysts; Autosomal dominant polycystic kidney disease:: overview; Autosomal dominant polycystic kidney disease:: clinical features; Autosomal dominant polycystic kidney disease:: diagnosis; Autosomal dominant polycystic kidney disease:: management (including strategies to slow progression); Management of intracranial aneurysms; Management of cystic liver disease; Autosomal dominant polycystic kidney disease in children and young adults; Autosomal recessive polycystic kidney disease; Bardet-Biedl syndrome and other ciliopathies; Hepatocyte nuclear factor-1B; Nephronophthisis and medullary cystic kidney disease:: overview; Nephronophthisis; Medullary cystic kidney disease and other autosomal dominant inherited interstitial kidney diseases; Oral-facial-digital type 1 syndrome; The molecular basis of glomerular basement membrane disorders; Alport syndrome:: overview; Alport syndrome:: clinical features; Alport syndrome:: diagnosis; Alport syndrome:: management; Thin glomerular basement membrane nephropathy and other collagenopathies; Nail patella syndrome; Molecular basis of nephrotic syndrome; Molecular basis of renal tumour syndromes; WT1 and its disorders; Tuberous sclerosis complex renal disease; Hypoxia-inducible factor and renal disorders; Von Hippel-Lindau disease; Molecular basis of complement-mediated renal disease; Inherited metabolic diseases and the kidney; Fabry disease:: overview and pathophysiology; Fabry disease:: clinical features; Fabry disease:: diagnosis; Fabry disease:: management and outcome; Cystinosis; Mitochondrial diseases and the kidney; APOL1 and renal disease; MYH9 and renal disease; Part 16:: The patient with structural and congenital abnormalities; Human kidney development; Kidney stem cells; Anatomical types of congenital anomalies:: overview of obstruction; Renal agenesis; Renal dysplasia; Renal hypoplasia; Normal variation in nephron numbers; Renal tubular dysgenesis; Congenital solitary functioning kidney; Duplex, ectopic, and horseshoe kidneys; Pelviureteric junction obstruction and megaureter; Posterior urethral valves; Vesicoureteric reflux and reflux nephropathy; The patient with urinary tract obstruction; Retroperitoneal fibrosis; Branchio-oto-renal syndrome; Townes-Brocks syndrome; Renal coloboma syndrome; Ante- and postnatal imaging to diagnose human kidney malformations; Part 17:: Drugs and renal disease; Drug-induced nephropathies; Drug dosing in chronic kidney disease; Drug dosing in acute kidney injury; Part 18:: Nephrology in the future; A global curriculum for training the next generation of nephrologists;