Concise Clinical Pharmacology: Cancer Therapeutics

1. The Principles of Cancer Therapeutics?normal cells versus tumor cells

2. Clinical Skills in Cancer Therapeutics

a. The Complete Medication History

b. Bringing pharmacokinetics to the bedside

c. Bringing pharmacodynamics to the bedside

d. Critically evaluating cancer drugs and therapeutic strategies

3. Drug Classes?Common and Unique Therapeutic Considerations

a. Antimetabolites

b. Alkylators

c. DNA Repair Targets

d. Antibiotics

e. Hormones

f. Receptors

4. Clinical Pharmacology in Specific Cancers

a. Lung cancer

b. Head/neck cancer

c. GI cancer

d. GU cancer

e. Bone and soft tissue cancer

f. Gynecological cancer

g. Nervous system cancer

h. Blood and Leukemia cancers

5. The Pathophysiologic Approach to Toxicity

6. The Assessment of Organs/systems in Toxicity

a. GI

b. GU

c. Pulmonary

d. Neurological

e. Hematologic

f. Dermatologic

7. Cancer Pharmacology in Concurrent Non-cancerous Disease

8. Patient Safety and Adverse Events

9. Clinical Trials and Novel Targets in Cancer Therapy

10. Tables of Drug Comparisons and Cross References:: Agents and Toxicities