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Gout and Other Crystal Arthropathies, by Dr. Robert Terkeltaub, presents the state-of-the-art, clinically-focused coverage you need to manage these increasingly prevalent diseases. Diagnose the full range of crystal arthropathies-including pseudogout, intercritical gout, hyperuricemia, and gouty arthritis-and treat your patients effectively with discussions of recently-approved drugs like Uloric and those currently under review, such as Kristexxa and Colcryst. With coverage of the latest therapies, preventions, and imaging studies, along with access to the fully searchable text online at www.expertconsult.com, this comprehensive resource is ideal for any physician who diagnoses, treats, and manages gout and crystal-induced arthropathies.
Opis
I
Foreword
II
Introduction
1
Pathology of Crystal Deposition Diseases
2
Synovial Fluid Crystal Analysis
3
Purine Metabolism in the Pathogenesis of Hyperuricemia, and Inborn Errors of Purine Metabolism Associated with Disease
4
Renal Basis of Hyperuricemia
5
Pathogenesis of Tophus Formation and Gouty Inflammation
6
Gout: Epidemiology and Risk Factors
7
Genetics of Gout
8
Diagnosis of Gout
9
Clinical Features of Gout
10
Treatment of Acute Gout
11
Diet, Alcohol, Obesity, and Hyperuricemia
12
Uricosuric Therapy of Hyperuricemia in Gout
13
Xanthine Oxidase Inhibitor Treatment of Hyperuricemia
14
Uricase Therapy of Gout
15
Prophylaxis of Attacks of Acute Gouty Arthritis
16
Overview of Gout Therapy Strategy and Targets and Management of Refractory Disease
17
Quality of Care in Gout
18
Health-Related Quality of Life and Outcome Measures in Gout
19
Asymptomatic Hyperuricemia: Cardiovascular and renal Implications
20
Pathogenesis and Molecular Genetics of Calcium Pyrophosphate Dihydrate Crystal Deposition Disease
21
Clinical Features, Diagnosis, and Treatment of CPPD Crystal Arthropathy
22
Basic Calcium Phosphate Crystal Arthropathy
23
Crystalline Disorders Associated with Renal Disease Including Oxalate Arthropathy
24
Plain Radiography and Advanced Imaging of Gout
25
Plain Radiography and Advanced Imaging of CPPD and Hydroxyapatite Deposition Diseases
26
Ultrasound in the Diagnosis of Crystal Deposition Disease
27
Developing the future of diagnosis and management of gout and other crystal deposition arthropathies