Goldman's Cecil Medicine

Cecil medicine, 24^th edition

Edited by Lee Goldman and Andrew I. Schafer

Part 1:: Social and Ethical Issues in Medicine

1:: Approach to Medicine, the Patient, and the Medical Profession:: Medicine as a Learned and Humane Profession

Lee Goldman

Editor:: Goldman, Lee

2:: Bioethics in the Practice of Medicine

Ezekiel Emanuel

Editor:: Goldman, Lee

3:: Care of Dying Patients and Their Families

Robert Arnold

Editor:: Goldman, Lee

4:: Cultural Context of Medicine

Victoria M. Taylor

Editor:: Goldman, Lee

5:: Socioeconomic Issues in Medicine

Steven Schroeder

Editor:: Goldman, Lee

Part 2:: Principles of Evaluation and Management

6:: Approach to the Patient:: History and Physical Examination

David Simel

Editor:: Goldman, Lee

7:: Approach to the Patient with Abnormal Vital Signs

David L. Schriger

Editor:: Goldman, Lee

8:: Statistical Interpretation of Data

Thomas Newman;Charles McCulloch

Editor:: Goldman, Lee

9:: Using Data for Clinical Decisions

Thomas Lee

Editor:: Goldman, Lee

10:: Measuring Health and Health Care

Stephan D. Fihn

Editor:: Goldman, Lee

11:: Quality of Care and Safety of Patients

Robert Wachter

Editor:: Goldman, Lee

12:: Comprehensive Chronic Disease Management

Edward H. Wagner

Editor:: Goldman, Lee

Part 3:: Preventive and Environmental Issues

13:: Counseling and Advising for Behavior Changes

F. Daniel Duffy

Editor:: Goldman, Lee

14:: The Periodic Health Examination

David Atkins

Editor:: Goldman, Lee

15:: Physical Activity

David M. Buchner

Editor:: Goldman, Lee

16:: Adolescent Medicine

Debra Katzman;Lawrence Neinstein

Editor:: Goldman, Lee

17:: Immunization

Walter Orenstein;William Atkinson

Editor:: Goldman, Lee

18:: Principles of Occupational and Environmental Medicine

Mark R. Cullen

Editor:: Goldman, Lee

19:: Radiation Injury

Arthur Upton

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20:: Bioterrorism

John G. Bartlett

Editor:: Goldman, Lee

21:: Chronic Poisoning:: Trace Metals and Others

Michael A McGuigan

Editor:: Goldman, Lee

Part 4:: Aging and Geriatric Medicine

22:: Epidemiology of Aging:: Implications of the Aging Society

Linda Fried

Editor:: Goldman, Lee

23:: Geriatric Assessment

David B. Reuben

Editor:: Goldman, Lee

24:: Common Clinical Sequelae of Aging

Kenneth Minaker

Editor:: Goldman, Lee

25:: Incontinence

Neil Resnick

Editor:: Goldman, Lee

26:: Neuropsychiatric Aspects of Aging

Sharon Inouye

Editor:: Goldman, Lee

27:: Delirium and Other Mental Status Problems in the Older Patient

Sharon Inouye

Editor:: Goldman, Lee

Part 5:: Clinical Pharmacology

28:: Principles of Drug Therapy

Robert Diasio

Editor:: Schafer, Andrew

29:: Pain

Srinivasa N Raja;Steven P Cohen

Editor:: Schafer, Andrew

30:: Biology of Addiction

Steven E. Hyman

Editor:: Schafer, Andrew

31:: Nicotine and Tobacco

Tony P. George

Editor:: Schafer, Andrew

32:: Alcohol Abuse and Dependence

Patrick OConnor

Editor:: Schafer, Andrew

33:: Drug Abuse and Dependence

Roger Weiss

Editor:: Schafer, Andrew

34:: Immunosuppressive Drugs, Including Corticosteroids

Grant Cannon

Editor:: Schafer, Andrew

35:: Biologic Agents

Cem Gabay

Editor:: Schafer, Andrew

36:: Prostaglandins, Aspirin, and Related Compounds

Carlo Patrono

Editor:: Schafer, Andrew

37:: Antithrombotic Therapy

Sam Schulman

Editor:: Schafer, Andrew

38:: Complementary and Alternative Medicine

Mary Charlson

Editor:: Schafer, Andrew

Part 6:: Genetics

39:: Principles of Genetics

Bruce Korf

Editor:: Schafer, Andrew

40:: Single-Gene and Chromosome Disorders

James R. Lupski

Editor:: Schafer, Andrew

41:: The Inherited Basis of Common Diseases

David Altshuler

Editor:: Schafer, Andrew

42:: Applications of Molecular Technologies to Clinical Medicine

Geoffrey Ginsburg;Geoffrey Ginsburg

Editor:: Schafer, Andrew

43:: Gene and Cell Therapy

Karl Skorecki

Editor:: Schafer, Andrew

Part 7:: Principles of Immunology and Inflammation

44:: The Innate and Adaptive Immune Systems

Cornelia Weyand;Jorg Goronzy

Editor:: Schafer, Andrew

45:: The Major Histocompatibility Complex

Peter K. Gregersen

Editor:: Schafer, Andrew

46:: Mechanisms of Immune-Mediated Tissue Injury

Jane Salmon

Editor:: Schafer, Andrew

47:: Mechanisms of Inflammation and Tissue Repair

Gary S. Firestein

Editor:: Schafer, Andrew

48:: Organ Transplantation

Megan Sykes

Editor:: Schafer, Andrew

49:: Complement in Health and Disease

David, R. Karp;V. Michael Holers

Editor:: Schafer, Andrew

Part 8:: Cardiovascular Disease

50:: Approach to the Patient with Possible Cardiovascular Disease

Lee Goldman

Editor:: Goldman, Lee

51:: Epidemiology of Cardiovascular Disease

Michael Klag

Editor:: Goldman, Lee

52:: Cardiac Function and Circulatory Control

Andrew Marks

Editor:: Goldman, Lee

53:: Radiology of the Heart

Murray G. Baron;Arthur E. Stillman

Editor:: Goldman, Lee

54:: Electrocardiography

Leonard I Ganz

Editor:: Goldman, Lee

55:: Echocardiography

Catherine Otto

Editor:: Goldman, Lee

56:: Non-invasive Cardiac Imaging

Christopher Kramer

Editor:: Goldman, Lee

57:: Catheterization and Angiography

Morton Kern

Editor:: Goldman, Lee

58:: Heart Failure:: Pathophysiology and Diagnosis

Barry Massie

Editor:: Goldman, Lee

59:: Heart Failure:: Management and Prognosis

John JV McMurray;Marc A. Pfeffer

Editor:: Goldman, Lee

60:: Diseases of the Myocardium and Endocardium

William McKenna;Perry Elliott

Editor:: Goldman, Lee

61:: Principles of Electrophysiology

Hugh Calkins

Editor:: Goldman, Lee

62:: Approach to the Patient with Suspected Arrhythmia

Jeffrey Olgin

Editor:: Goldman, Lee

63:: Approach to Cardiac Arrest and Life-Threatening Arrhythmias

Robert Myerburg

Editor:: Goldman, Lee

64:: Cardiac Arrhythmias with Supraventricular Origin

Peter Zimetbaum

Editor:: Goldman, Lee

65:: Ventricular Arrhythmias

William Stevenson

Editor:: Goldman, Lee

66:: Electrophysiologic Interventional Procedures and Surgery

Fred Morady

Editor:: Goldman, Lee

67:: Arterial Hypertension

Ronald Victor

Editor:: Goldman, Lee

68:: Pulmonary Hypertension

Valerie McLaughlin

Editor:: Goldman, Lee

69:: Congenital Heart Disease in Adults

Ariane Marelli

Editor:: Goldman, Lee

70:: Atherosclerosis, Thrombosis and Vascular Biology

Goran Hansson;Anders Hamsten

Editor:: Goldman, Lee

71:: Angina Pectoris

William Boden

Editor:: Goldman, Lee

72:: Acute Coronary Syndrome/Unstable Angina and Non-ST Elevation MI

Richard A. Lange

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73:: ST-Elevation Myocardial Infarction and Complications of MI

Jeffrey Anderson

Editor:: Goldman, Lee

74:: Interventional and Surgical Treatment of Coronary Artery Disease

Paul Teirstein;Bruce Lytle

Editor:: Goldman, Lee

75:: Valvular Heart Disease

Blase Carabello

Editor:: Goldman, Lee

76:: Infective Endocarditis

Vance Fowler Jr.;Arnold Bayer

Editor:: Goldman, Lee

77:: Pericardial Disease

William Little;Jae K. Oh

Editor:: Goldman, Lee

78:: Diseases of the Aorta

Eric Isselbacher

Editor:: Goldman, Lee

79:: Atherosclerotic Peripheral Arterial Disease

Christopher White

Editor:: Goldman, Lee

80:: Other Peripheral Arterial Diseases

Jeffrey Olin

Editor:: Goldman, Lee

81:: Peripheral Venous Disease

Jeffrey Ginsberg

Editor:: Goldman, Lee

82:: Cardiac Transplantation

Mariell Jessup

Editor:: Goldman, Lee

Part 9:: Respiratory Diseases

83:: Approach to the Patient with Respiratory Disease

Monica Kraft

Editor:: Goldman, Lee

84:: Imaging in Pulmonary Disease

Paul Stark

Editor:: Goldman, Lee

85:: Respiratory Structure and Function:: Mechanisms and Testing

Herbert Reynolds

Editor:: Goldman, Lee

86:: Disorders of Ventilatory Control

Atul Malhotra

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87:: Asthma

Jeffrey Drazen

Editor:: Goldman, Lee

88:: COPD

Dennis Niewoehner

Editor:: Goldman, Lee

89:: Cystic Fibrosis

Frank Accurso

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90:: Bronchiectasis, Atelectasis, Cysts, and Localized Lung Disorders

Anne ODonnell

Editor:: Goldman, Lee

91:: Alveolar Filling Disorders

Stephanie, M. Levine

Editor:: Goldman, Lee

92:: Interstitial Lung Disease

Ganesh Raghu

Editor:: Goldman, Lee

93:: Occupational Pulmonary Disorders

Susan Tarlo

Editor:: Goldman, Lee

94:: Physical and Chemical Injuries of the Lung

David C. Christiani

Editor:: Goldman, Lee

95:: Sarcoidosis

Michael Iannuzzi

Editor:: Goldman, Lee

96:: Acute Bronchitis and Tracheitis

Richard. P. Wenzel

Editor:: Goldman, Lee

97:: Overview of Pneumonia

Andrew H. Limper

Editor:: Goldman, Lee

98:: Pulmonary Embolism

Jeffrey Weitz

Editor:: Goldman, Lee

99:: Diseases of the Diaphragm, Chest Wall, Pleura, and Mediastinum

F. Dennis McCool

Editor:: Goldman, Lee

100:: Obstructive Sleep Apnea/Hypopnea Syndrome

Robert C. Basner

Editor:: Goldman, Lee

101:: Interventional and Surgical Approaches to Lung Disease

Armin Ernst;Malcom DeCamp

Editor:: Goldman, Lee

Part 10:: Critical Care Medicine

102:: Approach to the Patient in a Critical Care Setting

Deborah J. Cook

Editor:: Goldman, Lee

103:: Respiratory Monitoring in Critical Care

James Stoller;Nicholas S. Hill

Editor:: Goldman, Lee

104:: Acute Respiratory Failure

Leonard Hudson;Arthur Slutsky

Editor:: Goldman, Lee

105:: Mechanical Ventilation

Leonard Hudson;Arthur Slutsky

Editor:: Goldman, Lee

106:: Approach to the Patient with Shock

Emanuel Rivers

Editor:: Goldman, Lee

107:: Cardiogenic Shock

Steven Hollenberg

Editor:: Goldman, Lee

108:: Shock Syndromes Related to Sepsis

James Russell

Editor:: Goldman, Lee

109:: Disorders Due to Heat and Cold

William Winkenwerder, Jr;Michael N Sawka

Editor:: Goldman, Lee

110:: Acute Poisoning

Marsha D. Ford I

Editor:: Goldman, Lee

111:: Electric Injury

Basil A. Pruitt Jr.

Editor:: Goldman, Lee

112:: Medical Aspects of Trauma and Burn Care

Robert H. Demling;Jonathan Gates;Reza Askari

Editor:: Goldman, Lee

113:: Venomous Snake Bites

Steven A. Seifert;James Armitage

Editor:: Goldman, Lee

114:: Venoms and Poisons from Marine Organisms

Jay Fox

Editor:: Goldman, Lee

115:: Rhabdomyolysis

Francis OConnor;Patricia A. Deuster

Editor:: Goldman, Lee

Part 11:: Renal and Genitourinary Diseases

116:: Approach to the Patient with Renal Disease

Donald Landry

Editor:: Goldman, Lee

117:: Structure and Function of the Kidneys

Qais Al-Awqati;Jonathan Barasch

Editor:: Goldman, Lee

118:: Disorders of Sodium and Water Homeostasis

Karl Skorecki;Denny Ausiello

Editor:: Goldman, Lee

119:: Potassium Disorders

Julian Seifter

Editor:: Goldman, Lee

120:: Acid-Base Disorders

Julian Seifter

Editor:: Goldman, Lee

121:: Disorders of Magnesium and Phosphorus

Alan S. L. Yu

Editor:: Goldman, Lee

122:: Acute Kidney Injury

Bruce Molitoris

Editor:: Goldman, Lee

123:: Glomerular Disorders and Nephrotic Syndromes

Gerald B. Appel;Jai Radhakrishnan

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124:: Tubulointerstitial Diseases

Eric G Neilson

Editor:: Goldman, Lee

125:: Obstructive Uropathy

Mark Zeidel

Editor:: Goldman, Lee

126:: Diabetes and the Kidney

Raymond Harris

Editor:: Goldman, Lee

127:: Vascular Disorders of the Kidney

Thomas D. DuBose, Jr.

Editor:: Goldman, Lee

128:: Nephrolithiasis

Gary C Curhan

Editor:: Goldman, Lee

129:: Cystic Kidney Diseases

M. Amin Arnaout

Editor:: Goldman, Lee

130:: Hereditary Nephropathies and Abnormalities of the Urinary Tract

Lisa Guay-Woodford

Editor:: Goldman, Lee

131:: Benign Prostate Disease and Prostatitis

Michael Barry;Mary McNaughton-Collins

Editor:: Goldman, Lee

132:: Chronic Kidney Disease

William Mitch

Editor:: Goldman, Lee

133:: Treatment of Irreversible Renal Failure

Nina Tolkoff-Rubin

Editor:: Goldman, Lee

Part 12::Gastrointestinal Diseases

134:: Approach to the Patient with Gastrointestinal Disease

Kenneth McQuaid

Editor:: Goldman, Lee

135:: Diagnostic Imaging Procedures in Gastroenterology

Perry J Pickhardt

Editor:: Goldman, Lee

136:: Gastrointestinal Endoscopy

P. Jay Pasricha

Editor:: Goldman, Lee

137:: Gastrointestinal Hemorrhage and Occult Gastrointestinal Bleeding

Dennis M. Jensen

Editor:: Goldman, Lee

138:: Disorders of Gastrointestinal Motility

Michael Camilleri

Editor:: Goldman, Lee

139:: Functional Gastrointestinal Disorders:: Irritable Bowel Syndrome, Dyspepsia, and Noncardiac Chest Pain

Emeran Mayer

Editor:: Goldman, Lee

140:: Diseases of the Esophagus

David A. Katzka;Gary Falk

Editor:: Goldman, Lee

141:: Acid Peptic Disease

Ernst Kuipers;Martin Blaser

Editor:: Goldman, Lee

142:: Approach to the Patient with Diarrhea and Malabsorption

Carol E. Semrad

Editor:: Goldman, Lee

143:: Inflammatory Bowel Disease

Gary R. Lichtenstein

Editor:: Goldman, Lee

144:: Inflammatory and Anatomic Diseases of theINtestine, Peritoneum, Mesentery, and Omentum

Charlene Prather

Editor:: Goldman, Lee

145:: Vascular Diseases of the GI Tract

Stephen Hauser

Editor:: Goldman, Lee

146:: Pancreatitis

Chris E. Forsmark

Editor:: Goldman, Lee

147:: Diseases of the Rectum and Anus

Robert D. Madoff

Editor:: Goldman, Lee

Part 13:: Diseases of the Liver, Gallbladder, and Bile Ducts

148:: Approach to the Patient with Liver Disease

Paul Martin

Editor:: Goldman, Lee

149:: Approach to the Patient with Jaundice or Abnormal Liver Test Results

Paul Berk;Kevin Korenblat

Editor:: Goldman, Lee

150:: Acute Viral Hepatitis

Jean-Michel Pawlotsky;Heiner Wedemeyer

Editor:: Goldman, Lee

151:: Chronic Viral Hepatitis

Jean-Michel Pawlotsky;John McHutchinson

Editor:: Goldman, Lee

152:: Toxin- and Drug-Induced Liver Disease

William Lee

Editor:: Goldman, Lee

153:: Inherited and Metabolic Hepatic Disorders

Bruce R Bacon

Editor:: Goldman, Lee

154:: Bacterial, Parasitic, Fungal, and Granulomatous Liver Diseases

Karen Krok;K. Rajender Reddy

Editor:: Goldman, Lee

155:: Alcoholic and NonAlcoholic Steatohepatitis

Naga P. Chalasani

Editor:: Goldman, Lee

156:: Cirrhosis and Its Sequelae

Guadalupe Garcia-Tsao

Editor:: Goldman, Lee

157:: Hepatic Failure and Liver Transplantation

Emmet Keeffe

Editor:: Goldman, Lee

158:: Diseases of the Gallbladder and Bile Ducts

Nezam H. Afdhal

Editor:: Goldman, Lee

Part 14:: Hematologic Diseases

159:: Hematopoiesis and Hematopoietic Growth Factors

Kenneth Kaushansky

Editor:: Schafer, Andrew

160:: The Peripheral blood Smear

Barbara Bain

Editor:: Schafer, Andrew

161:: Approach to the Anemias

H. Franklin Bunn

Editor:: Schafer, Andrew

162:: Microcytic and Hypochromic Anemias

Gordon Ginder

Editor:: Schafer, Andrew

163:: Autoimmune and Intravascular Hemolytic Anemias

Robert Schwartz

Editor:: Schafer, Andrew

164:: Hemolytic Anemias:: Red Cell Membrane and Metabolic Defects

Patrick Gallagher

Editor:: Schafer, Andrew

165:: Hemoglobinopathies:: The Thalassemias

Maria Cappellini

Editor:: Schafer, Andrew

166:: Sickle Cell Disease and Associated Hemoglobinopathies

Martin Steinberg

Editor:: Schafer, Andrew

167:: Megaloblastic Anemias

Asok C. Antony

Editor:: Schafer, Andrew

168:: Aplastic Anemia and Related Conditions

Grover Bagby

Editor:: Schafer, Andrew

169:: Polycythemias, Essential Thrombocythemia and Primary Myelobfibrosis

Ayalew Tefferi

Editor:: Schafer, Andrew

170:: Leukopenia and Leukocytosis

Nancy Berliner

Editor:: Schafer, Andrew

171:: Approach to the Patient with Lymphadenopathy and Splenomegaly

James Armitage

Editor:: Schafer, Andrew

172:: Disorders of Phagocyte Function

Michael Glogauer

Editor:: Schafer, Andrew

173:: Eosinophilic Syndromes

Marc Rothenberg

Editor:: Schafer, Andrew

174:: Approach to the Patient with Bleeding and Thrombosis

Andrew Schafer

Editor:: Schafer, Andrew

175:: Thrombocytopenia

Charles Abrams

Editor:: Schafer, Andrew

176:: Von Willebrands Disease and Abnormalties of Vascular Function

William Nichols

Editor:: Schafer, Andrew

177:: Hemorrhagic Disorders:: Coagulation Factor Deficiencies

Margaret Ragni

Editor:: Schafer, Andrew

178:: Hemorrhagic Disorders:: DIC, Liver Failure, and Vitamin K Deficiency

Andrew Schafer

Editor:: Schafer, Andrew

179:: Thrombotic Disorders:: Hypercoagulable States

Andrew Schafer

Editor:: Schafer, Andrew

180:: Transfusion Medicine

Lawrence Goodnough

Editor:: Schafer, Andrew

181:: Hematopoietic Stem Cell Transplantation

Julie Vose

Editor:: Schafer, Andrew

Part 15:: Oncology

182:: Approach to the Patient with Cancer

Michael Perry

Editor:: Schafer, Andrew

183:: The Epidemiology of Cancer

Michael Thun

Editor:: Schafer, Andrew

184:: The Genetics of Cancer

Henry Lynch

Editor:: Schafer, Andrew

185:: The Biology of Cancer

Kenneth H Cowan;Jeffrey A Moscow

Editor:: Schafer, Andrew

186:: Endocrine Manifestations of Tumors:: Ectopic Hormone Production

Robert F. Gagel

Editor:: Schafer, Andrew

187:: Paraneoplastic Syndromes and Other Non-Neoplastic Effects of Cancer

Hope Rugo

Editor:: Schafer, Andrew

188:: Myelodysplasia Syndrome

Alan List;Rami Komrokji;Eric Padron

Editor:: Schafer, Andrew

189:: The Acute Leukemias

Frederick R Appelbaum

Editor:: Schafer, Andrew

190:: The Chronic Leukemias

Hagop Kantarjian;Susan OBrien

Editor:: Schafer, Andrew

191:: Non-Hodgkins Lymphomas

James Armitage

Editor:: Schafer, Andrew

192:: Hodgkins Lymphomas

Joseph Connors

Editor:: Schafer, Andrew

193:: Plasma Cell Disorders

S. Vincent Rajkumar

Editor:: Schafer, Andrew

194:: Amyloidosis

Morrie Gertz

Editor:: Schafer, Andrew

195:: Tumors of the CNS and Intracranial Hypertension and Hypotension

Lisa DeAngelis

Editor:: Schafer, Andrew

196:: Head and Neck Cancer

Marshall R. Posner

Editor:: Schafer, Andrew

197:: Lung Cancer and Other Pulmonary Neoplasms

David S Ettinger

Editor:: Schafer, Andrew

198:: Neoplasma of the Esophagus and Stomach

Anil Rustgi

Editor:: Schafer, Andrew

199:: Neoplasms of the Large and Small Intestine

Charles Blanke;Douglas Faigel

Editor:: Schafer, Andrew

200:: Pancreatic Cancer

Margaret Tempero

Editor:: Schafer, Andrew

201:: Pancreatic Endocrine Tumors

Robert T. Jensen

Editor:: Schafer, Andrew

202:: Liver and Biliary Tract Tumors

Lewis Roberts

Editor:: Schafer, Andrew

203:: Tumors of the Kidney, Bladder, Ureters, and Renal Pelvis

Dean Bajorin

Editor:: Schafer, Andrew

204:: Breast Cancer and Differential Diagnosis of Benign Lesions

Nancy Davidson

Editor:: Schafer, Andrew

205:: Gynecologic Cancers

Maurie Markman

Editor:: Schafer, Andrew

206:: Testicular Cancer

Lawrence Einhorn

Editor:: Schafer, Andrew

207:: Prostate Cancer

Eric Small

Editor:: Schafer, Andrew

208:: Bone Tumors:: Primary and Metastatic Lesions

Karen H. Antman

Editor:: Schafer, Andrew

209:: Sarcomas of Soft Tissue

George D. Demetri

Editor:: Schafer, Andrew

210:: Melanoma and Nonmelanoma Skin Cancers

Lynn Schuchter

Editor:: Schafer, Andrew

211:: Cancer of Unknown Primary Origin

John Hainsworth

Editor:: Schafer, Andrew

Part 16:: Metabolic Diseases

212:: Approach to Inborn Errors of Metabolism

Louis Elsas II

Editor:: Schafer, Andrew

213:: Disorders of Lipid Metabolism

Clay F. Semenkovich

Editor:: Schafer, Andrew

214:: Glycogen Storage Diseases

Joseph I. Wolfsdorf;David A. Weinstein

Editor:: Schafer, Andrew

215:: Lysosomal Storage Diseases

Ellen Sidransky;Donna Krasnewich

Editor:: Schafer, Andrew

216:: Homocystinuria and Hyperhomocysteinemia

Bruce Barshop

Editor:: Schafer, Andrew

217:: The Porphyrias

Karl Anderson

Editor:: Schafer, Andrew

218:: Wilsons Disease

Stephen Kaler

Editor:: Schafer, Andrew

219:: Iron Overload (Hemochromatosis)

Bruce R Bacon

Editor:: Schafer, Andrew

Part 17::Nutritional Diseases

220:: Nutritions Interface with Health and Disease

Douglas Heimburger

Editor:: Schafer, Andrew

221:: Nutritional Assessment

Bruce Bistrian

Editor:: Schafer, Andrew

222:: Protein-Energy Malnutrition

Samuel Klein

Editor:: Schafer, Andrew

223:: Enteral Nutrition

Stephen McClave

Editor:: Schafer, Andrew

224:: Parenteral Nutrition

Greet Van den Berghe;Alexander Wilmer

Editor:: Schafer, Andrew

225:: Vitamins, Trace Minerals, and Other Micronutrients

Joel B. Mason

Editor:: Schafer, Andrew

226:: Eating Disorders

Marsha Marcus

Editor:: Schafer, Andrew

227:: Obesity

Michael Jensen

Editor:: Schafer, Andrew

Part 18:: Endocrine Diseases

228:: Approach to the Patient with Endocrine Disease

David R. Clemmons

Editor:: Schafer, Andrew

229:: Principles of Endocrinology

David R. Clemmons

Editor:: Schafer, Andrew

230:: Neuroendocrinology and the Neuroendocrine System

Mark E. Molitch

Editor:: Schafer, Andrew

231:: Anterior Pituitary

Mark E. Molitch

Editor:: Schafer, Andrew

232:: Posterior Pituitary

Joseph G. Verbalis

Editor:: Schafer, Andrew

233:: Thyroid

Paul Ladenson;Matthew Kim

Editor:: Schafer, Andrew

234:: Adrenal Cortex

Lynnette Nieman

Editor:: Schafer, Andrew

235:: The Adrenal Medulla, Catecholamines, and Pheochromocytoma

William F. Young

Editor:: Schafer, Andrew

236:: Type I Diabetes Mellitus

Robert Sherwin;Silvio Inzucchi

Editor:: Schafer, Andrew

237:: Type II Diabetes Mellitus

Robert Sherwin;Silvio Inzucchi

Editor:: Schafer, Andrew

238:: Hypoglycemia/Pancreatic Islet Cell Disorders

Stephen N. Davis

Editor:: Schafer, Andrew

239:: Polyglandular Disorders

Henry Kronenberg

Editor:: Schafer, Andrew

240:: Multiple-Organ Syndromes:: Carcinoid Syndrome

Kenneth Hande

Editor:: Schafer, Andrew

241:: Disorders of Sexual Differentiation

Perrin C. White

Editor:: Schafer, Andrew

242:: The Testis and Male Sexual Function

Ronald Swerdloff

Editor:: Schafer, Andrew

243:: Ovaries, Development and Menstrual Cycle

Robert W Rebar

Editor:: Schafer, Andrew

244:: Reproductive Endocrinology/Infertility

Robert W Rebar

Editor:: Schafer, Andrew

Part 19:: Womens Health

245:: Approach to Womens Health

Karen Freund

Editor:: Schafer, Andrew

246:: Contraception

Daniel Mishell Jr.

Editor:: Schafer, Andrew

247:: Common Medical Problems in Pregnancy

Karen Rosene Montella

Editor:: Schafer, Andrew

248:: Menopause

Deborah Grady;Elizabeth Barrett-Connor

Editor:: Schafer, Andrew

249:: Interpersonal Violence

Harriet MacMillan;Gene Feder

Editor:: Schafer, Andrew

Part 20:: Diseases of Bone and Mineral Metabolism

250:: Mineral and Bone Homeostasis

Murray Favus

Editor:: Schafer, Andrew

251:: Osteoporosis

Cliff Rosen

Editor:: Schafer, Andrew

252:: Osteomalacia and Rickets

Robert Weinstein

Editor:: Schafer, Andrew

253:: The Parathyroid Glands, Hypercalcemia, and Hypocalcemia

John Wysolmerski;Karl Insogna

Editor:: Schafer, Andrew

254:: Medullary Thyroid Carcinoma and Calcitonin

Samuel Wells Jr.

Editor:: Schafer, Andrew

255:: Pagets Disease of Bone

David Roodman

Editor:: Schafer, Andrew

256:: Osteonecrosis, Osteosclerosis/Hyperostosis and Other Disorders of Bone

Michael P. Whyte

Editor:: Schafer, Andrew

Part 21:: Diseases of Allergy and Clinical Immunology

257:: Approach to the Patient with Allergic or Immunologic Disease

Stephen I Wasserman

Editor:: Schafer, Andrew

258:: Primary Immunodeficiency Diseases

Mark Ballow

Editor:: Schafer, Andrew

259:: Allergic Rhinitis and Sinusitis

Larry Borish

Editor:: Schafer, Andrew

260:: Urticaria and Angioedema

Stephen Dreskin

Editor:: Schafer, Andrew

261:: Systemic Anaphylaxis, Food Allergy, and Insect Sting Allergy

Lawrence Schwartz

Editor:: Schafer, Andrew

262:: Drug Allergy

Leslie Grammer

Editor:: Schafer, Andrew

263:: Mastocytosis

Cem Akin

Editor:: Schafer, Andrew

Part 22:: Rheumatic Diseases

264:: Approach to the Patient with Rheumatic Disease

William Arend;George Lawry

Editor:: Schafer, Andrew

265:: Laboratory Testing in the Rheumatic Diseases

David Pisetsky

Editor:: Schafer, Andrew

266:: Imaging Studies in the Rheumatic Diseases

Lynne Steinbach

Editor:: Schafer, Andrew

267:: Connective Tissue Structure and Function

Richard Loeser

Editor:: Schafer, Andrew

268:: Inherited Diseases of Connective Tissues

Reed Edwin Pyeritz

Editor:: Schafer, Andrew

269:: The Systemic Autoinflammatory Diseases

Daniel Kastner

Editor:: Schafer, Andrew

270:: Osteoarthritis

Nancy Lane;Thomas J. Schnitzer

Editor:: Schafer, Andrew

271:: Bursitis, Tendonitis, and Other Periarticular Disorders, and Sports Medicine

Josephn J. Biundo

Editor:: Schafer, Andrew

272:: Rheumatoid Arthritis

James ODell

Editor:: Schafer, Andrew

273:: The Spondyloarthropathies

Robert Inman

Editor:: Schafer, Andrew

274:: Systemic Lupus Erythematosus

Mary Crow

Editor:: Schafer, Andrew

275:: Scleroderma (Systemic Sclerosis)

John Varga

Editor:: Schafer, Andrew

276:: Sjogrens Syndrome

M. Eric Gershwin;Stanley Naguwa

Editor:: Schafer, Andrew

277:: Polymyositis and Dermatomyositis

Frederick, W. Miller

Editor:: Schafer, Andrew

278:: The Systemic Vasculitides

John, H Stone

Editor:: Schafer, Andrew

279:: Polymyalgia Rheumatica and Temporal Arteritis

Steven Paget;Robert Spiera

Editor:: Schafer, Andrew

280:: Infections of Bursae, Joints, and Bones

Eric Matteson;Douglas Osmon

Editor:: Schafer, Andrew

281:: Crystal Deposition Diseases

N.Lawrence Edwards

Editor:: Schafer, Andrew

282:: Fibromyalgia and Chronic Fatigue Syndrome

Robert Bennett

Editor:: Schafer, Andrew

283:: Systemic Diseases in which Arthritis is a Feature

Sterling,G. West

Editor:: Schafer, Andrew

284:: Multifocal Fibrosclerosis

Wilmer Sibbitt Jr.

Editor:: Schafer, Andrew

285:: Surgical Treatment of Joint Diseases

C. Ronald Mackenzie;Edwin Su

Editor:: Schafer, Andrew

Part 23:: Infectious Diseases

286:: Introduction to Microbial Disease - Host-Pathogen Interactions

William Scheld

Editor:: Schafer, Andrew

287:: Principles of Anti-Infective Therapy

George M. Eliopoulos

Editor:: Schafer, Andrew

288:: Approach to Fever or Suspected Infection in the Normal Host

James Leggett

Editor:: Schafer, Andrew

289:: Approach to Fever and Suspected Infection in the Compromised Host

Kieren Marr

Editor:: Schafer, Andrew

290:: Approach to the Patient with Healthcare-associated Infections

Neil Fishman

Editor:: Schafer, Andrew

291:: Approach to the Patient with Suspected Enteric Infection

Herbert DuPont

Editor:: Schafer, Andrew

292:: Approach to the Patient with Urinary Tract Infection

Ragnar Norrby

Editor:: Schafer, Andrew

293:: Approach to the Patient with a Sexually Transmitted Disease

Myron S. Cohen

Editor:: Schafer, Andrew

294:: Approach to the Patient Before and After Travel

Paul, M. Arguin

Editor:: Schafer, Andrew

295:: Antibacterial Therapy

George Drusano

Editor:: Schafer, Andrew

296:: Staphylococcal Infections

Henry Chambers

Editor:: Schafer, Andrew

297:: Streptococcus Pneumoniae Infections

Lionel Mandell

Editor:: Schafer, Andrew

298:: Non-Pneumococcal Streptococcal Infections, Rheumatic Fever

Donald Low

Editor:: Schafer, Andrew

299:: Enterococcal Infections

Trish Perl;Eli N. Perencevich

Editor:: Schafer, Andrew

300:: Diphtheria and Other Corynebacteria Infections

Roland Sutter

Editor:: Schafer, Andrew

301:: Listeriosis

Bennett Lorber

Editor:: Schafer, Andrew

302:: Anthrax

Daniel Lucey

Editor:: Schafer, Andrew

303:: Erysipelothrix Infections

Annette C. Reboli

Editor:: Schafer, Andrew

304:: Clostridial Infections

Dale Gerding

Editor:: Schafer, Andrew

305:: Diseases Caused by Non-spore-forming Anaerobic Bacteria

Itzhak Brook

Editor:: Schafer, Andrew

306:: Neisseria Meningitidis Infections

David Stephens

Editor:: Schafer, Andrew

307:: Neisseria Gonorhoeaea Infections

Matthew Golden

Editor:: Schafer, Andrew

308:: Haemophilus and Moraxella Infections

Michael Simberkoff

Editor:: Schafer, Andrew

309:: Chancroid

Stanley Spinola

Editor:: Schafer, Andrew

310:: Cholera and Other Vibrio Infections

Carlos Seas

Editor:: Schafer, Andrew

311:: Campylobacter Infections

Ban Mishu Allos

Editor:: Schafer, Andrew

312:: Escherichia Enteric Infections

Richard Guerrant;Ted Steiner

Editor:: Schafer, Andrew

313:: Infections due to other Members of the Enterobacteriaceae, including Management of Multi-Drug Resistant Strains

David Paterson

Editor:: Schafer, Andrew

314:: Pseudomonas and Related Gram-Negative Bacillary Infections

Gerald Pier

Editor:: Schafer, Andrew

315:: Other Non-Fermenting Gram-Negatives:: Acinetobacter and Stenotrophomonas sp

Robert Bonomo

Editor:: Schafer, Andrew

316:: Salmonella Infections (Including Typhoid Fever)

John A. Crump

Editor:: Schafer, Andrew

317:: Shigellosis

Gerald T. Keusch

Editor:: Schafer, Andrew

318:: Brucellosis

Eduardo Gotuzzo

Editor:: Schafer, Andrew

319:: Tularemia and Other Francisella Infections

William Schaffner

Editor:: Schafer, Andrew

320:: Plague and Other Yersinia Infections

Kenneth Gage

Editor:: Schafer, Andrew

321:: Whooping Cough and Other Bordetella Infections

Erik L. Hewlett

Editor:: Schafer, Andrew

322:: Legionella Infections

Thomas Marrie

Editor:: Schafer, Andrew

323:: Disease Caused by Bartonella Species

Didier Raoult;Jean-Marc Rolain

Editor:: Schafer, Andrew

324:: Granuloma Inguinale (Donovanosis)

Edward W. Hook III

Editor:: Schafer, Andrew

325:: Mycoplasma Infections

Stephen G. Baum

Editor:: Schafer, Andrew

326:: Diseases Caused by Chlamydiae

William, M. Geisler

Editor:: Schafer, Andrew

327:: Treponema Infection (Syphillis)

Edward W. Hook III

Editor:: Schafer, Andrew

328:: Nonsyphilitic Treponematoses

Edward W. Hook III

Editor:: Schafer, Andrew

329:: Lyme Disease

Gary Wormser

Editor:: Schafer, Andrew

330:: Relapsing Fever and Other Borrelia Infections

William Petri

Editor:: Schafer, Andrew

331:: Leptospirosis

Albert Ko

Editor:: Schafer, Andrew

332:: Tuberculosis

Jerrold Ellner

Editor:: Schafer, Andrew

333:: The Nontuberculous Mycobacteria

Steven Holland

Editor:: Schafer, Andrew

334:: Leprosy (Hansens Disease)

Joel Ernst

Editor:: Schafer, Andrew

335:: Rickettsia Infections

Didier Raoult

Editor:: Schafer, Andrew

336:: Zoonoses

Stuart Levin

Editor:: Schafer, Andrew

337:: Actinomycosis

Itzhak Brook

Editor:: Schafer, Andrew

338:: Nocardiosis

Frederick Southwick

Editor:: Schafer, Andrew

339:: Systemic Antifungal Agents

David A. Stevens

Editor:: Schafer, Andrew

340:: Histoplasmosis

Carol Kauffman

Editor:: Schafer, Andrew

341:: Coccidioidomycosis

John N. Galgiani

Editor:: Schafer, Andrew

342:: Blastomycosis

Carol Kauffman

Editor:: Schafer, Andrew

343:: Paracoccidioidomycosis

Carol Kauffman

Editor:: Schafer, Andrew

344:: Cryptococcoisis

Carol Kauffman

Editor:: Schafer, Andrew

345:: Sporotrichosis

Carol Kauffman

Editor:: Schafer, Andrew

346:: Candidiasis

Carol Kauffman

Editor:: Schafer, Andrew

347:: Aspergillosis

Thomas Walsh

Editor:: Schafer, Andrew

348:: Mucormycosis

Dimitrios Kontoyiannis

Editor:: Schafer, Andrew

349:: Pneumocystis Penumonia

Joseph A. Kovacs

Editor:: Schafer, Andrew

350:: Mycetoma

Dimitrios Kontoyiannis

Editor:: Schafer, Andrew

351:: Dematiaceous Fungal Infections

Peter Pappas

Editor:: Schafer, Andrew

352:: Antiparasitic Therapy

Richard Pearson

Editor:: Schafer, Andrew

353:: Malaria

Philip Rosenthal;Moses R. Kamya

Editor:: Schafer, Andrew

354:: African Trypanosomiasis (Sleeping Sickness)

William Petri

Editor:: Schafer, Andrew

355:: American Trypanosomiasis (Chagas Disease)

Louis V. Kirchhoff

Editor:: Schafer, Andrew

356:: Leishmaniasis

Simon Croft

Editor:: Schafer, Andrew

357:: Toxoplasmosis

Jose, G Montoya

Editor:: Schafer, Andrew

358:: Crytosporidiosis

Richard Guerrant;Aldo A. M. Lima

Editor:: Schafer, Andrew

359:: Giardiasis

Theodore E. Nash

Editor:: Schafer, Andrew

360:: Amebiasis

William Petri

Editor:: Schafer, Andrew

361:: Babesiosis and Other Protozoan Diseases

Sam Telford III

Editor:: Schafer, Andrew

362:: Cestode Infections

A. Clinton White;Enrico Brunetti

Editor:: Schafer, Andrew

363:: Schistosomiasis (Bilharziasis)

Aldo A. M. Lima;Edgar Carvalho

Editor:: Schafer, Andrew

364:: Liver, Intestinal, and Lung Fluke Infections

Eduardo Gotuzzo

Editor:: Schafer, Andrew

365:: Intestinal Nematodes

David Diemert

Editor:: Schafer, Andrew

366:: Tissue Nematodes

David Diemert

Editor:: Schafer, Andrew

367:: Arthropods and Leeches

Dirk Elston

Editor:: Schafer, Andrew

368:: Antiviral Therapy (Non-HIV)

John Beigel

Editor:: Goldman, Lee

369:: The Common Cold

Ronald B. Turner

Editor:: Goldman, Lee

370:: Respiratory Syncytial Virus

Edward Walsh

Editor:: Goldman, Lee

371:: Parainfluenza Viral Diseases

Kathryn Edwards;Geoffrey A. Weinberg

Editor:: Goldman, Lee

372:: Influenza

Frederick Hayden

Editor:: Goldman, Lee

373:: Adenovirus Diseases

John J. Treanor

Editor:: Goldman, Lee

374:: Coronaviruses

Larry Anderson

Editor:: Goldman, Lee

375:: Measles (Rubeola Virus Infection)

Marty Weisse;Capt. Mark Papania

Editor:: Goldman, Lee

376:: Rubella (German Measles)

Susan Reef

Editor:: Goldman, Lee

377:: Mumps

John Gnann

Editor:: Goldman, Lee

378:: Slow Virus Infections

Avindra Nath

Editor:: Goldman, Lee

379:: Parvovirus

Neal S. Young

Editor:: Goldman, Lee

380:: Smallpox, Monkeypox, and Other Poxvirus Infections

Inger Damon

Editor:: Goldman, Lee

381:: Papillomavirus

John M. Douglas Jr.

Editor:: Goldman, Lee

382:: Herpes Simplex Virus Infections

Richard J. Whitley

Editor:: Goldman, Lee

383:: Varicella (Chickenpox, Shingles)

Jeffrey Cohen

Editor:: Goldman, Lee

384:: Cytomegalovirus

W. Lawrence Drew

Editor:: Goldman, Lee

385:: Epstein-Barr Virus Infection

Robert Schooley

Editor:: Goldman, Lee

386:: Human T-Cell Lymphotropic Viruses Type I and II

William Blattner

Editor:: Goldman, Lee

387:: Enteroviruses

José R Romero

Editor:: Goldman, Lee

388:: Rotaviruses, Noroviruses, and Other GI Viruses

Harry Greenberg;Manuel Franco

Editor:: Goldman, Lee

389:: Viral Hemorrhagic Fevers

Daniel G. Bausch

Editor:: Goldman, Lee

390:: Arthropod-borne Viruses Causing Fever and Rash

Stanley Naides

Editor:: Goldman, Lee

391:: Anthropod-borne Viruses Affecting the CNS

Thomas Bleck

Editor:: Goldman, Lee

Part 24:: HIV and the Acquired Immunodeficiency Syndrome

392:: Epidemiology of HIV Infection and AIDS

Thomas Quinn

Editor:: Schafer, Andrew

393:: Immunopathogenesis of HIV Infection

Robert Siliciano

Editor:: Schafer, Andrew

394:: Biology of Human Immunodeficiency Viruses

George Shaw

Editor:: Schafer, Andrew

395:: Prevention of HIV Infection

Carlos Del Rio

Editor:: Schafer, Andrew

396:: Treatment of HIV Infection and AIDS

Henry Masur

Editor:: Schafer, Andrew

397:: Gastrointestinal Manifestions of HIV and AIDS

Christine Wanke;Tamsin Knox

Editor:: Schafer, Andrew

398:: Pulmonary Manifestations of HIV and AIDS

Laurence Huang

Editor:: Schafer, Andrew

399:: Skin Manifestations in Patients with HIV Infection

Toby Maurer

Editor:: Schafer, Andrew

400:: Hematology/Oncology in Patients with HIV Infection

Paul A. Volberding

Editor:: Schafer, Andrew

401:: Neurologic Complications of HIV Infection

Avindra Nath

Editor:: Schafer, Andrew

402:: Immune reconstitution Inflammatory Syndrome in HIV/AIDS

Robert Colebunders;Martyn French

Editor:: Schafer, Andrew

Part 25:: Neurology

403:: Approach to the Patient with Neurological Disease

Ralph Jozefowicz;Michael Aminoff

Editor:: Goldman, Lee

404:: Psychiatric Disorders in Medical Practice

Jeffrey M. Lyness

Editor:: Goldman, Lee

405:: Headaches and Other Head Pain

Kathleen Digre

Editor:: Goldman, Lee

406:: Head and Spinal Cord Injury

Geoffrey Ling

Editor:: Goldman, Lee

407:: Spine, Disc, Spinal Cord and Spinal Root Disease

Richard, L Barbano

Editor:: Goldman, Lee

408:: Regional Cerebral Dysfunction

David Knopman

Editor:: Goldman, Lee

409:: Alzheimers Disease and Other Dementias

David Knopman

Editor:: Goldman, Lee

410:: The Epilepsies

Samuel Wiebe

Editor:: Goldman, Lee

411:: Coma, Persistent Vegetative State and Brain Death

James L. Bernat

Editor:: Goldman, Lee

412:: Disorders of Sleep

Mark W. Mahowald

Editor:: Goldman, Lee

413:: Approach to Cerebrovascular Diseases

Justin Zivin

Editor:: Goldman, Lee

414:: Ischemic Cerebrovascular Disease

Justin Zivin

Editor:: Goldman, Lee

415:: Hemorrhagic Cerebrovascular Disease

Justin Zivin

Editor:: Goldman, Lee

416:: Parkinsonism

Anthony E Lang

Editor:: Goldman, Lee

417:: Other Movement Disorders

Anthony Lang

Editor:: Goldman, Lee

418:: ALS and Other Motor Neuron Diseases

Pamela J Shaw

Editor:: Goldman, Lee

419:: Multiple Sclerosis and Demyelinating Conditions of the CNS

Peter Calabresi

Editor:: Goldman, Lee

420:: Meningitis:: Bacterial, Viral, and Other

Avindra Nath

Editor:: Goldman, Lee

421:: Brain Abscess and Parameningeal Infections

Avindra Nath;Joseph, R Berger

Editor:: Goldman, Lee

422:: Acute Viral Encephalitis

Allen Aksamit Jr.

Editor:: Goldman, Lee

423:: Poliomyelitis

Allen Aksamit Jr.

Editor:: Goldman, Lee

424:: Prion Diseases

Patrick J. Bosque

Editor:: Goldman, Lee

425:: Nutritional and Alcohol-Related Neurologic Diseases

Barbara Koppel

Editor:: Goldman, Lee

426:: Congenital, Developmental and Neurocutaneous Disorders

Jonathan W. Mink

Editor:: Goldman, Lee

427:: Autonomic Disorders and Their Management

William P. Cheshire Jr.

Editor:: Goldman, Lee

428:: Peripheral Neuropathies

Michael Shy

Editor:: Goldman, Lee

429:: Muscle Diseases

Patrick F. Chinnery

Editor:: Goldman, Lee

430:: Disorders of Neuromuscular Transmission

Angela Vincent

Editor:: Goldman, Lee

Part 26:: Eye, Ear, Nose, and Throat Diseases

431:: Diseases of the Visual System

Myron Yanoff;J. Douglas Cameron

Editor:: Goldman, Lee

432:: Neuro-Ophthalmology

Robert W. Baloh;Joanna Jen

Editor:: Goldman, Lee

433:: Diseases of the Mouth and Salivary Glands

Troy Daniels

Editor:: Goldman, Lee

434:: Approach to the Patient with Nose, Sinus, and Ear Disorders

Andrew Murr

Editor:: Goldman, Lee

435:: Smell and Taste

Robert W. Baloh;Joanna Jen

Editor:: Goldman, Lee

436:: Hearing and Equilibrium

Robert W. Baloh;Joanna Jen

Editor:: Goldman, Lee

437:: Throat Disorders

Thomas Tami

Editor:: Goldman, Lee

Part 27:: Medical Consultation

438:: Principles of Preoperative Consultation and Co-Management

Gerald Smetana

Editor:: Goldman, Lee

439:: Preoperative Evaluation

Steven Cohn

Editor:: Goldman, Lee

440:: Overview of Anesthesia

Jeanine Wiener-Kronish;Lee Fleisher

Editor:: Goldman, Lee

441:: Postoperative Care and Complications

Don Redelmeier

Editor:: Goldman, Lee

442:: Medical Consultation in Psychiatry

Peter Manu

Editor:: Goldman, Lee

Part 28:: Skin Diseases

443:: Structure and Function of Skin

David Norris

Editor:: Goldman, Lee

444:: Examination of the Skin and an Approach to Diagnosing Skin Diseases

Cheryl Armstrong

Editor:: Goldman, Lee

445:: Principles of Therapy

Victoria Werth

Editor:: Goldman, Lee

446:: Eczema, Photosensitivity, and papulosquamous (including fungal) Diseases and Figurate Erythemas

Henry Lim

Editor:: Goldman, Lee

447:: Macular, Vesiculobullous, and Pustular Diseases

Neil Korman

Editor:: Goldman, Lee

448:: Urticaria, Drug Hypersensitivity Rashes, Nodules and Tumors, and Atrophic Diseases

Madeleine Duvic

Editor:: Goldman, Lee

449:: Infections, Hyper-and Hypopigmentation, Regional Dermatology, and Distinctive Lesions in Black Skin

Jean Bolognia

Editor:: Goldman, Lee

450:: Diseases of Hair and Nails

Antonella Tosti

Editor:: Goldman, Lee

Appendix:: Laboratory Reference Intervals and Values

Appendix:: Reference Intervals and Laboratory Values

Ronald J. Elin

Editor:: Goldman, Lee