Macrophages are widely distributed innate immune cells, which play a pivotal role not only in the primary response to pathogens but also in adaptive immune response, in tissue repair and in the maintenance of local tissue homoeostasis. This book includes current research in the life cycle, functions and diseases associated with macrophages. Topics discussed include macrophages as regulatory and effector cells in the immune system; macrophages from human pluripotent stem cells; mucosal macrophage phenotype and functionality in homoeostasis and pathology; macrophage plasticity and polarization; defective macrophage function in Crohns disease; macrophages in viral infection and atherosclerosis; and macrophage polarization in the course and treatment of autoimmune diseases.
Macrophages & Tuberculosis; Nitric Oxide:: The Double-Edged Sword of Macrophages in the Immune Defense; Macrophages from Human Pluripotent Stem Cells; Mucosal Macrophages:: Phenotype & Functionality in Homeostasis & Pathology; Macrophage Plasticity & Polarization:: Cell Signaling Mechanisms & Roles in Immunity; Mechanisms of Macrophage-Dependent Regulation of Hepatocyte Functions; HIV-1 Tat Protein Induces TNF-a & IL-10 in Human Monocyte/Macrophage Cells; Diverse Functionality of Macrophages after Axonal Injury to the Central Nervous System; Macrophage Stimulation & β-D-Glucans as Biological Response Modifiers:: The Role in Experimental Tumor Development; Hepatic Macrophages & Macrophages with Different Functions in Hepaticfibrosis; Macrophage in Inflammation & Healing:: Relationships with Biomaterials; Macrophage Polarization in the Course & Treatment of Autoimmune Disease; The Functional Diversity of Kupffer Cells; Defective Macrophage Function in Crohns Disease; Macrophages in Viral Infection; Macrophage & Atherosclerosis; Arginine Transport in Human Monocytes/Macrophages; Multiple Mechanisms Underlying Silent Cleanup of Apoptotic Cells; The Roles of CD68 Expressing Macrophage Lineage Cells in Engineered Dental Pulp Tissues; Macrophages:: Life Cycle, Functions & Participation in the Pathogenesis of Atherosclerosis.
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