In this issue of Hematology/Oncology Clinics, guest editor Dr. P. Leif Bergsagel brings his considerable expertise to the topic of New Developments in Myeloma. With the advent of next generation sequencing and immune profiling technologies, marked advances have been made recently in the understanding of the molecular and immune pathogenesis of multiple myeloma. Yet even with these advances, there is a continual search for new therapeutic approaches. In this issue, top experts discuss a full range of clinically relevant topics in this complex and fast-changing field.
Molecular Pathogenesis of Multiple Myeloma: Clinical Implications Immune-Pathogenesis of Myeloma Smoldering Multiple Myeloma: Observation Versus Control Versus Cure Cereblon-targeting ligase degraders in myeloma: Mechanisms of action and resistance Proteasome Inhibitors in Multiple Myeloma: Biological Insights on Mechanisms of Action or Resistance Informed by Functional Genomics Monoclonal Antibodies in the Treatment of Multiple Myeloma Bispecific Antibodies in the Treatment of Multiple Myeloma Chimeric Antigen Receptor T Cells in the Treatment of Multiple Myeloma Is There Still a Role for Stem Cell Transplantation in Multiple Myeloma? Role of Consolidation and Maintenance Management of Newly Diagnosed Multiple Myeloma Today, and in the Future Impact of Clonal Heterogeneity in Multiple Myeloma Measurable Residual Disease and Decision-Making in Multiple Myeloma Approach to High-Risk Multiple Myeloma New Therapies on the Horizon for Relapsed Refractory Multiple Myeloma Immunocompetent Mouse Models of Multiple Myeloma: Therapeutic Implications
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