Our understanding of myeloproliferative neoplasms (MPN) disorders, a group of clonal haematological malignancies characterized by excessive accumulation of one or more myeloid cell lineages, has grown considerably over the past four decades.Myeloproliferative Neoplasms offers a detailed evidence-based guide to MPNs in an easily accessible format, structured to facilitate learning specialist information by presenting core information in bite size chunks. Each chapter summarises the state-of-the art preclinical and clinical knowledge, and its impact on the clinical management of patients with MPNs. This practical guide, written by experts in the field, is essential reading for oncologists, haematologists, and other health care professionals interested in the field of MPNs.
History of the myeloproliferative neoplasms; Genomic landscape of myeloproliferative neo-plasms; Pathogenesis of myeloproliferative neoplasms; Haematopathology of myeloproliferative neoplasms; Prognostic factors of chronic myeloid leukaemia; Molecular risk stratification of Myeloproliferative Neoplasms; Chronic myeloid leukaemia; Polycythaemia vera; Myelofibrosis; Essential thrombocythemia; Systemic mastocytosis; Myelodysplastic syndromes/myeloproliferative neoplasms; Eosinophilia-associated myeloproliferative neoplasms; Transformation of myeloproliferative neoplasms to acute leukaemia; Monitoring efforts in myeloproliferative neoplasms; Stem cell transplantation for BCR-ABL1-postive and negative myeloproliferative neoplasms; Assessment of disease burden in patients with myeloproliferative neoplasms; Clinical trials in bcr-abl1-negative myeloproliferative neo-plasms;