Williams Hematology

1 Approach to the patient

2 Examination of the blood

3 Examination of the marrow

4 The marrow and hematopoietic microenvironment

5 The lymphoid tissues

6 Hematology of the newborn

7 Hematology during pregnancy

8 Hematology in the aged

9 Genetic principles and molecular biology

10 Cytogenetics and gene rearrangement

11 Apoptosis

12 Cell cycle regulation

13 Signal transduction pathways

14 The cluster of differentiation (CD) antigens

15 Hematopoietic stem cells, progenitor cells, and cytokines

16 The inflammatory response

17 The innate immune system

18 The adaptive immune system and dendritic cells

19 Pharmacology and toxicity of antineoplastic drugs

20 Treatment of infections in the immunocompromised host

21 Principles of antithrombotic therapy

22 Principles of hematopoietic stem cell transplantation

23 Principles of immune cell therapy

24 Principles of vaccine therapy

25 Principles of therapeutic apheresis

26 Principles of gene transfer for therapy

27 Pain management

28 Morphology of the erythron

29 Composition of the erythrocyte

30 Production of erythrocytes

31 Destruction of erythrocytes

32 Clinical manifestations and classification of erythrocyte disorders

33 Aplastic anemia

34 Pure red cell aplasia

35 Anemia of chronic renal disease

36 Anemia of endocrine disorders

37 The congenital dyserythropoietic anemias

38 Paroxysmal nocturnal hemoglobinuria

39 Disorders of folic acid and cobalamin metabolism: the megaloblastic anemias

40 Disorders of iron metabolism

41 Anemia resulting from other nutritional deficiencies

42 Anemia associated with marrow infiltration

43 Anemia of chronic disease

44 Disorders of the red cell membrane: hereditary spherocytosis, elliptocytosis, and related disorders

45 Disorders of red cells resulting from enzyme abnormalities

46 Disorders of globin synthesis: the thalassemias

47 Disorders of hemoglobin structure: sickle cell anemia and related abnormalities

48 Methemoglobinemia and other causes of cyanosis

49 Hemolytic anemia resulting from physical injury to red cells

50 Hemolytic anemia due to chemical and physical agents

51 Hemolytic anemia due to infections with microorganisms

52 Hemolytic anemia due to immune injury

53 Alloimmune hemolytic disease of the newborn

54 Acute blood loss anemia

55 Hypersplenism and hyposplenism

56 Primary and secondary polycythemia (Erythrocytosis)

57 The hematologic aspects of porphyria

58 Hereditary and acquired sideroblastic anemias

59 Morphology of neutrophils, eosinophils, and basophils

60 Composition of neutrophils

61 Production, distribution, and fate of neutrophils

62 Eosinophils and their disorders

63 Basophils and mast cells, and their disorders

64 Classification and clinical manifestations of neutrophil disorders

65 Neutropenia and neutrophilia

66 Disorders of neutrophil function

67 Morphology of monocytes and macrophages

68 Biochemistry and function of monocytes and macrophages

69 Production, distribution, and fate of monocytes and macrophages

70 Classification and clinical manifestations of disorders of monocytes and macrophages

71 Monocytosis and monocytopenia

72 Inflammatory and malignant histiocytosis

73 Lipid storage diseases

74 Morphology of lymphocytes and plasma cells

75 Composition and biochemistry of lymphocytes and plasma cells

76 Lymphopoiesis

77 Functions of B lymphocytes and plasma cells in immunoglobin

78 Functions of T lymphocytes: T-cell receptors for antigen

79 Functions of natural killer cells

80 Classification and clinical manifestations of lymphocytosis and plasma cell disorders

81 Lymphocytosis and lymphocytopenia

82 Immunodeficiency diseases

83 Acquired immunodeficiency syndrome (AIDS)

84 Mononucleosis syndromes

85 Classification and clinical manifestations of the clonal myeloid disorders

86 Myelodysplastic disorders (Clonal cytopenias and oligoblastic leukemia)

87 Acute myelogenous leukemia

88 Chronic myelogenous leukemia and related disorders

89 Idiopathic myelofibrosis (agnogenic myeloid metaplasia)

90 Classification of malignant lymphoid disorders

91 Acute lymphocytic leukemia

92 Chronic lymphocytic leukemia and related diseases

93 Hairy cell leukemia

94 Large granular lymphocytic leukemia

95 Pathology of malignant lymphomas

96 The non-Hodgkin lymphomas

97 Hodgkin lymphoma

98 Plasma cell neoplasms: General considerations

99 Essential monoclonal gammopathies

100 Plasma cell myeloma

101 Amyloidosis

102 Macroglobulinemia

103 Heavy-chain disease

104 Megakaryopoiesis and thrombopoiesis

105 Platelet morphology, biochemistry and function

106 Molecular biololgy and biochemistry of the coagulation factors and pathways of hemostasis

107 Control of coagulation reactions

108 Vascular function in hemostasis

109 Classification, clinical manifestations and evaluation of disorders of hemostasis

110 Thrombocytopenia

111 Thrombocytosis and essential thrombocythemia

112 Hereditary qualitative platelet disorders

113 Acquired qualitative platelet disorders

114 The vascular purpuras

115 Hemophilia A and hemophilia B

116 Inherited deficiencies of coagulation factors II, V, VII, XI and XIIIa

117 Hereditary abnormalities of fibrinogen

118 von Willebrand disease

119 Antibody-mediated coagulation factor deficiencies

120 Hemostatic dysfunction related to liver diseases and liver transplantation

121 Disseminated intravascular coagulation

122 Hereditary thrombophilias

123 The antiphospholipid syndrome

124 Antibody-mediated thrombotic disorders: thrombotic thrombocytopenia purpura and heparin induced thrombocytopenia

125 Venous thrombosis

126 Arterial thrombosis

127 Fibrinolysis and thrombolysis

128 Erythrocyte antigens and antibodies

129 Human leukocyte and platelet antigens

130 Blood procurement and screening

131 Preservation and clinical use of erythrocytes and whole blood

132 Preservation and clinical use of platelets