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Practical Genetics for the Ob-Gyn

Practical Genetics for the Ob-Gyn

9780071797214
532,92 zł
506,28 zł Zniżka 26,64 zł Brutto
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Opis

Publishers Note:: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.



Understand the clinical application of genetics in ob-gyn practice with this case-based text

This up-to-date resource surveys the modern field of genetics and provides you with a practical understanding of its clinical uses.

Whether determining who is pre-disposed to disease, howa patient will respond to therapy, or what the optimal cancer treatment might be based on tumor profiles, this is the only guide to help efficiently interpret and utilize genetic data across the full spectrum of ob-gyn clinical scenarios.

Practical Genetics for the Ob-Gyn is organized around three central themes:: basic genetic principles, clinical applications of ob-gyn practice, and common methods of genetic testing. Opening each chapter is a patient case study that establishes a realistic clinicalcontext for the subsequent genetics-based material addressed.

Szczegóły produktu
McGraw Hill / Medical
55409
9780071797214
9780071797214

Opis

Rok wydania
2014
Numer wydania
1
Oprawa
miękka foliowana
Liczba stron
192
Wymiary (mm)
152 x 229
Waga (g)
268

  • I. Basic Genetic Principles

    1. Gene Structure and Function

    2. Chromosome Structure and Function

    3. Patterns of Inheritance

    a. Mendelian inhereditance (Include clinical examples for each)

    i. Autosomal dominant

    ii. Autosomal recessive

    iii. Co-dominant

    iv. X-linked

    b. Non-mendelian inhereditance (include clinical examples)

    i. Hereditary unstable DNA

    ii. Imprinting

    iii. Uniparental disomy

    iv. Mitochondrial inhereditance

    v. Germ line mosaicism

    c. Multifactorial and Polygenic Inhereditance

    4. Chromosomal Abnormalities

    a. Aneuploidy

    b. Deletion, Duplication, and Inversions

    II. Clinical Genetics in the Context of Obstetrics and Gynecology

    5. Taking a family history

    6. Principles of genetic counseling

    7. Preconception counseling

    8. Screening for genetic disorders in pregnancy

    9. Methods of prenatal diagnosis

    10. Common fetal malformations diagnosed by ultrasound

    11. Gynecologic disorders with a genetic causation

    12. Hereditary cancer syndromes

    13. Disorders of sexual differentiation

    14. Infertility and pregnancy loss

    III. Methods of Genetic Testing

    15. Traditional cytogenetic testing

    16. Molecular cytogenetic testing

    a. Fluorescent in-situ hybridization

    b. Microarrays

    17. Molecular diagnostic testing

    a. Southern blot analysis

    b. Polymerase chain reaction

    c. DNA sequencing

    d. New approaches to diagnostic testing

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