DNA methylation is a cryptic phenomenon that invokes the methylation of the cytosines in nuclear DNA and is responsible for a wide variety of essential processes, starting from cellular differentiation (embryogenesis), transposon silencing, miRNA dependent methylation and gene regulation. This book presents an overview of different aspects of DNA methylation with a focus on its basic principles and mechanisms and gene silencing. Also discussed, is the role of DNA methylation in plants; epigenetic control of circadian clock operation; photoperiodic flowering; and DNA methylation in cancer and its role in multiple sclerosis.
Preface; Introduction to DNA Methylation & its Role in Carcinogenesis; DNA Methylation:: A Cause or a Consequence of Gene Silencing?; The Role of DNA Methylation in Plants; Epigenetic Control of Circadian Clock Operation; Epigenetic Regulation of Photoperiodic Flowering; Index.
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