Bacteria are a large group of unicellular micro-organisms. Most bacteria have a single circular chromosome that can range in size. DNA is organised into chromosomes and, in organisms other than bacteria, it is found only in the cell nucleus. Deoxyribonucleic acid(DNA)is a nucleic acid that contains the genetic instructions used in the development and functioning of all known living organisms and some viruses. Their main role is the long-term storage of information. DNA is often compared to a set of blueprints or a code, since it contains the instructions needed to construct other components of cells. This book presents current research on bacterial DNA, DNA polymerase and DNA helicases.
Preface; Codon Usage and Gene Expression In Bacteria; Maillard Reaction and Spontaneous Mutagenesis in Escherichia Coli; Nucleoid Architecture and Dynamics in Bacteria; Genome Reduction in Bacillus Subtilis and Enhanced Productivities of Recombinant Proteins; Molecular Detection and Characterization of Food and Waterborne Viruses; hTERT in Cancer Chemotherapy:: A Novel Target of Histone Deacetylase Inhibitors; Dynamics of DNA Polymerase; Modeling DNA translocation and unwinding by helicase RecG; De Novo DNA Synthesis by DNA Polymerase; Bacteriophage Phi 29 DNA Polymerase:: An Outstanding Replicase; Bacterial Replicative DNA Helicases; Effect of Substrate Traps on Hhepatitis C Virus NS3 Helicase Catalyzed DNA Unwinding:: Evidence for Enzyme Catalyzed Strand Exchange; Discovery of Orphan Helicases and Deorphanization by Genome-Wide Analyses in Two Model Organisms; Index.
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