Essentials of Medical Pharmacology

Section 1 General Pharmacological Principles

• Introduction, Routes of Drug Administration
• Pharmacokinetics:: Membrane Transport, Absorption and Distribution of Drugs
• Pharmacokinetics:: Metabolism and Excretion of Drugs, Kinetics of Elimination
• Pharmacodynamics:: Mechanism of Drug Action; Receptor Pharmacology
• Aspects of Pharmacotherapy, Clinical Pharmacology and Drug Development
• Adverse Drug Effects

Section 2 Drugs Acting on Autonomic Nervous System
Autonomic Nervous System:: General Considerations

• Cholinergic Transmission and Cholinergic Drugs
• Anticholinergic Drugs and Drugs Acting on Autonomic Ganglia
• Adrenergic Transmission and Adrenergic Drugs
• Antiadrenergic Drugs (Adrenergic Receptor Antagonists) and Drugs for Glaucoma

Section 3 Autacoids and Related Drugs

• Histamine and Antihistaminics
• 5-Hydroxytryptamine, its Antagonists and Drug Therapy of Migraine
• Prostaglandins, Leukotrienes (Eicosanoids) and Platelet Activating Factor
• Nonsteroidal Anti Inflammatory Drugs and Antipyretic-Analgesics
• Anti Rheumatoid and Antigout Drugs

Section 4 Respiratory System Drugs

• Drugs for Cough and Bronchial Asthma

Section 5 Hormones and Related Drugs Introduction
Introduction

• Anterior Pituitary Hormones
• Thyroid Hormones and Thyroid Inhibitors
• Insulin, Oral Antidiabetic Drugs and Glucagon
• Corticosteroids
• Androgens and Related Drugs, Drugs for Erectile Dysfunction
• Estrogens, Progestins and Contraceptives
• Oxytocin and Other Drugs Acting on Uterus
• Hormones and Drugs Affecting Calcium Balance

Section 6 Drugs Acting on Peripheral (Somatic) Nervous System

• Skeletal Muscle Relaxants
• Local Anaesthetics

Section 7 Drugs Acting on Central Nervous System

• General Anaesthetics
• Ethyl and Methyl Alcohols
• Sedative-Hypnotics
• Antiepileptic Drugs
• Antiparkinsonian Drugs
• Drugs Used in Mental Illness:: Antipsychotic and Antimanic Drugs
• Drugs Used in Mental Illness:: Antidepressant and Antianxiety Drugs
• Opioid Analgesics and Antagonists
• CN S Stimulants and Cognition Enhancers

Section 8 Cardiovascular Drugs

• Cardiac Electrophysiological Considerations
• Drugs Affecting Renin-Angiotensin System
• Nitric Oxide and Vasoactive Peptide Signal Molecules
• Cardiac Glycosides and Drugs for Heart Failure
• Antiarrhythmic Drugs
• Antianginal and Other Anti-ischaemic Drugs
• Antihypertensive Drugs

Section 9 Drugs Acting on Kidney
Relevant Physiology of Urine Formation

• Diuretics
• Antidiuretics

Section 10 Drugs Affecting Blood and Blood Formation

• Haematinics and Erythropoietin
• Drugs Affecting Coagulation, Bleeding and Thrombosis
• Hypolipidaemic Drugs

Section 11 Gastrointestinal Drugs

• Drugs for Peptic Ulcer and Gastroesophageal Reflux Disease
• Antiemetic, Prokinetic and Digestant Drugs
• Drugs for Constipation and Diarrhoea

Section 12 Antimicrobial Drugs

• Antimicrobial Drugs:: General Considerations
• Sulfonamides, Cotrimoxazole and Quinolones
• Beta-Lactam Antibiotics
• Tetracyclines and Chloramphenicol (Broad-Spectrum Antibiotics)
• Aminoglycoside Antibiotics
• Macrolide, Lincosamide, Glycopeptide and Other Antibacterial Antibiotics; Urinary Antiseptics
• Antitubercular Drugs
• Antileprotic Drugs
• Antifungal Drugs
• Antiviral Drugs (Non-retroviral)
• Antiviral Drugs (Anti-retrovirus)
• Antimalarial Drugs
• Antiamoebic and Other Antiprotozoal Drugs
• Anthelmintic Drugs

Section 13 Chemotherapy of Neoplastic Diseases

• Anticancer Drugs

Section 14 Miscellaneous Drugs

• Immunosuppressant Drugs
• Drugs Acting on Skin and Mucous Membranes
• Antiseptics, Disinfectants and Ectoparasiticides
• Chelating Agents
• Vitamins
• Vaccines, Antisera and Immuneglobulins
• Drug Interactions

Appendices
Appendix 1:: Solution to Problem Directed Study
Appendix 2:: Prescribing in Pregnancy
Appendix 3:: Drugs in Breastfeeding
Appendix 4:: Drugs and Fixed Dose Combinations Banned in India
Selected References for Further Reading
Index