Neurobiology of Addiction highlights some of the most promising research areas of the rapidly expanding field of addiction. It will be useful as a practical tool for clinicians, research investigators, and trainees-both in addiction and in other illnesses with overlapping mechanisms-as well as an informative resource for non-technical readers who are interested in addiction or mental health policy. The editors have combined their areas of expertise to provide a unique perspectiveinto the prevention and treatment of addictive disorders. Their approach addresses addiction in the broader context of behavioral processes and survival-related adaptations, focusing on its neurobiological precursors and drawing parallels between addictions and other recurrent or progressivepsychiatric disorders. The book also emphasizes resilience, clinical contexts of addictive behavior, and treatment strategies that target its underlying neurobiological mechanisms.
Preface; Contributors; 1. Beyond Drugs: Addictions in the Context of Recurrent/Progressive Psychiatric Illness; Alan C. Swann; 2. Behavioral Mechanisms in Addiction; Margaret C. Wardle, Jin H. Yoon, Anka A. Vujanovic, Michael F. Weaver, Scott D. Lane, and Joy M. Schmitz; 3. The biology of nicotine addiction and factors that differentiate youth who smoke from those who do not; Felicia R. Carey and Anna V. Wilkinson; 4. Resilience and Opiate Misuse; Sameer Hassamal, Divya Ramesh, and F. Gerard Moeller; 5. Alcohol-Related Disorders: Adaptations and Progression to Disordered Drinking; Therese A Kosten, Colin Haile, Marijn Lijffijt, and Alan C. Swann; 6. The Neurobiology of Behavioral Sensitization; Jeffery D. Steketee; 7. Stress and Addiction; Marijn Lijffijt; 8. The Neurobiology of Behavioral Addictions: Sexual Addiction; Donald L. Hilton, Jr., Stefanie Carnes, and Todd L. Love; 9. Norepinephrine as a therapeutic target for cocaine-use disorder; Colin N. Haile, Thomas F. Newton, and Thomas R. Kosten; 10. Cannnabis, endocannabinoids, and mechanisms of addiction; Christopher Rodgman and Christopher D. Verrico; 11. Cocaine addiction therapy pharmacogenetics; David A. Nielsen; 12. Increasing the Information Yield from Clinical Trials in Addictions:; Bayesian Statistics, Adaptive Designs, and Biomarker Evaluation; Charles Green, Robert Suchting, Nuvan Rathnayaka, Margaret C. Wardle, and Joy M. Schmitz; 13. Mechanisms of Sensitization to Stress, Affective Episodes, and Abused Substances: Implications for Treatment and Prevention; Robert M. Post;
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