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Harrison's Principles of Internal Medicine with DVD 17e

9780071466332
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Opis

Introducing the most dramatically revised edition of Harrisons ever!

Now with NEW bonus DVD with 37 chapters and more than 500 brand new images and video clips!

A Doodys Core Title ESSENTIAL PURCHASE!

5 STAR DOODYS REVIEW
The book is for anyone who has the remotest association with the practice of medicine, be they internists, surgeons, nurses, technical staff, or counselors. This is the authority, and in a time of readily available but not always accurate information, this is the one source that can be relied upon....This is one of the absolute pillars of any medical library. It is the final word in internal medicine and we all owe a debt of gratitude to the editors and contributors who have created this extraordinary authority in medicine.--Doodys Review Service

MORE THAN TRUSTED, BEYOND ESSENTIAL . . .

The #1 selling medical textbook worldwide, Harrisons has defined internal medicine for millions of clinicians and students. The new 17th Edition retains Harrisons acclaimed balance of pathobiology, cardinal signs and manifestations of disease, and best approaches to patient management, yet has been massively updated to give you an innovative array of bold new features and content. If ever there was one must-have resource for clinicians and students -- this is it!

UNMATCHED EXPERTISE AT YOUR FINGERTIPS

As an unprecedented amount of medical information bombards you and your patients, where do you go to sort it out and make sense of it all? When your patients request clarification on something theyve ?printed off,? where do you turn for expert explanations? The same trusted resource physicians and students have turned to for more than fifty years:: Harrisons Principles of Internal Medicine. Now more than ever, trust Harrisons to filter and clarify the exploding knowledge base, to highlight the breakthroughs, and to deliver a clear, balanced distillation of the best and most current information on which to base clinical decisions.

THE MOST EXCITING AND EXTENSIVELY REVISED EDITION EVER!

Here are just a few of the reasons why the new 17th Edition of Harrisons is the best edition yet::

  • Bonus companion DVD featuring:: 37 new ?e-chapters?; over 500 brand-new radiological, laboratory, and clinical images, including complete atlases; state-of-the-art video clips; an Image Bank of nearly all the illustrations contained in the parent text, and much more
  • Expanded, modernized illustration program with more than 800 brand-new, additional illustrations--a 60% increase over the previous edition
  • Dozens of brand new chapters on vital topics in medical education and clinical practice:: Global Issues in Medicine:: Patient Safety and Health Quality; Health Disparities:: Atlas of EKGs; Clinical Management of Obesity; Atlas of Hematology; Atlases of Chest, Neurological, and Cardiovascular Radiology; and much more! Also included is a complete new section on biological foundations and emerging clinical applications of regenerative medicine!
  • Brand new, reader-friendly text design optimizes the full-color format
  • An expanded, innovative focus on global health
  • NEW Global Advisory Board comprising 11 prominent medical experts from Asia, India, Europe, and South America
  • Revision of the popular On Line Learning Center, which offers more skill-sharpening self-assessment questions and answers, plus additional case studies for helping you apply Harrisons content to the daily care of patients
  • Harrisons related products are available in a full suite of formats to meet all your educational and clinical needs. Harrisons Practice of Medicine is a complete database of more than 700 clinical topics formatted for use at the point of care. The Harrisons Manual of Medicine is one of the most popular and heavily used handbook-sized resources in internal medicine. The Harrisons Self-Assessment and Board Review features more than 1000 board-type cases and questions and highlights the use of Harrisons as a great board prep resouce.
Szczegóły produktu
37752
9780071466332
9780071466332

Opis

Rok wydania
2008
Numer wydania
17
Oprawa
twarda
Liczba stron
2919
Wymiary (mm)
220 x 285
Waga (g)
4280
  • Contents

    Contributors

    Preface

    PART 1::

    Introduction to Clinical Medicine

    1 The Practice of Medicine
    The Editors

    2 Global Issues in Medicine
    Jim Yong Kim / Paul Farmer

    3 Decision-Making in Clinical Medicine
    Daniel B. Mark

    4 Screening and Prevention of Diseases
    Gary J. Martin

    5 Principles of Clinical Pharmacology
    Dan M. Roden

    6 Women?s Health
    Andrea Dunaif

    7 Medical Disorders during Pregnancy
    Robert L. Barbieri / John T. Repke

    8 Medical Evaluation of the Surgical Patient
    Wei C. Lau / Kim A. Eagle

    9 Geriatric Medicine
    Lisa B. Caruso / Rebecca A. Silliman

    10 Complementary and Alternative Medicine
    Stephen E. Straus

    11 Palliative and End-of-Life Care
    Ezekiel J. Emanuel / Joshua Hauser / Linda L. Emanuel

    e1 The Safety and Quality of Health Care
    David W. Bates

    e2 Economic Considerations in the Practice of Medicine
    David Meltzer

    e3 Racial and Ethnic Disparities in Health Care
    Joseph R. Betancourt / David Blumenthal

    e4 Ethical Issues in Clinical Medicine
    Bernard Lo

    PART 2::

    Cardinal Manifestations and Presentation of Diseases

    Section 1:: Pain

    12 Pain:: Pathophysiology and Management
    Howard L. Fields / Joseph B. Martin

    13 Chest Discomfort
    Thomas H. Lee

    14 Abdominal Pain
    William Silen

    15 Headache
    Peter J. Goadsby / Neil H. Raskin

    16 Back and Neck Pain
    John W. Engstrom

    Section 2::

    Alterations in Body Temperature

    17 Fever and Hyperthermia
    Charles A. Dinarello / Reuven Porat

    18 Fever and Rash
    Elaine T. Kaye / Kenneth M. Kaye

    e5 Atlas of Rashes Associated with Fever
    Kenneth M. Kaye / Elaine T. Kaye

    19 Fever of Unknown Origin
    Jeffery A. Gelfand / Michael V. Callahan

    20 Hypothermia and Frostbite
    Daniel F. Danzl

    Section 3::

    Nervous System Dysfunction

    21 Syncope
    Mark D. Carlson

    22 Dizziness and Vertigo
    Robert B. Daroff

    23 Weakness and Paralysis
    Michael J. Aminoff

    24 Gait and Balance Disorders
    Lewis Sudarsky

    25 Numbness, Tingling, and Sensory Loss
    Michael J. Aminoff / Arthur K. Asbury

    26 Confusion and Delirium
    S. Andrew Josephson / Bruce L. Miller

    e6 Memory Loss
    Thomas D. Bird / Bruce L. Miller

    27 Aphasia, Memory Loss, and Other Focal Cerebral Disorders
    M.-Marsel Mesulam

    28 Sleep Disorders
    Charles A. Czeisler / John W. Winkelman / Gary S. Richardson

    Section 4::

    Disorders of Eyes, Ears, Nose, and Throat

    29 Disorders of the Eye
    Jonathan C. Horton

    30 Disorders of Smell, Taste, and Hearing
    Anil K. Lalwani

    31 Pharyngitis, Sinusitis, Otitis, and Other Upper Respiratory Tract Infections
    Michael A. Rubin / Ralph Gonzales / Merle A. Sande

    32 Oral Manifestations of Disease
    Samuel C. Durso

    e7 Atlas of Oral Manifestations of Disease
    Samuel C. Durso / Janet A. Yellowitz / Jane C. Atkinson

    Section 5::

    Alterations in Circulatory and Respiratory Functions

    33 Dyspnea and Pulmonary Edema
    Richard M. Schwartzstein

    34 Cough and Hemoptysis
    Steven E. Weinberger / David A. Lipson

    35 Hypoxia and Cyanosis
    Eugene Braunwald

    36 Edema
    Eugene Braunwald / Joseph Loscalzo

    e8 Approach to the Patient with a Heart Murmur
    Patrick T. O?Gara / Eugene Braunwald

    37 Palpitations
    Joseph Loscalzo

    Section 6::

    Alterations in Gastrointestinal Function

    38 Dysphagia
    Raj K. Goyal

    39 Nausea, Vomiting, and Indigestion
    William L. Hasler

    40 Diarrhea and Constipation
    Michael Camilleri / Joseph A. Murray

    41 Weight Loss
    Carol M. Reife

    42 Gastrointestinal Bleeding
    Loren Laine

    43 Jaundice
    Daniel S. Pratt / Marshall M. Kaplan

    44 Abdominal Swelling and Ascites
    Robert M. Glickman / Roshini Rajapaksa

    Section 7::

    Alterations in Renal and Urinary Tract Function

    45 Azotemia and Urinary Abnormalities
    Bradley M. Denker / Barry M. Brenner

    e9 Atlas of Urinary Sediments and Renal Biopsies
    Agnes B. Fogo / Eric G. Neilsen

    46 Fluid and Electrolyte Disturbances
    Gary G. Singer / Barry M. Brenner

    47 Hypercalcemia and Hypocalcemia
    Sundeep Khosla

    48 Acidosis and Alkalosis
    Thomas B. DuBose, Jr.

    Section 8::

    Alterations in Sexual Function and Reproduction

    49 Sexual Dysfunction
    Kevin T. McVary

    50 Hirsutism and Virilization
    David A. Ehrmann

    51 Menstrual Disorders and Pelvic Pain
    Janet E. Hall

    Section 9:: Alterations in the Skin

    52 Approach to the Patient with a Skin Disorder
    Thomas J. Lawley / Kim B. Yancey

    53 Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders
    Calvin O. McCall / Thomas J. Lawley

    54 Skin Manifestations of Internal Disease
    Jean L. Bolognia / Irwin M. Braverman

    55 Immunologically Mediated Skin Diseases
    Kim B. Yancey / Thomas J. Lawley

    56 Cutaneous Drug Reactions
    Jean-Claude Roujeau / Robert S. Stern / Bruce C. Wintroub

    57 Photosensitivity and Other Reactions to Light
    David R. Bickers

    e10 Atlas of Skin Manifestations of Internal Disease
    Thomas J. Lawley / Stephen Templeton

    Section 10::

    Hematologic Alterations

    58 Anemia and Polycythemia
    John W. Adamson / Dan L. Longo

    59 Bleeding and Thrombosis
    Barbara A. Konkle

    60 Enlargement of Lymph Nodes and Spleen
    Patrick H. Henry / Dan L. Longo

    61 Disorders of Granulocytes and Monocytes
    Steven M. Holland /John I. Gallin

    e11 Atlas of Hematology and Analysis of Peripheral Blood Smears
    Dan L. Longo

    PART 3:: Genetics and Disease

    62 Principles of Human Genetics
    J. Larry Jameson / Peter Kopp

    63 Chromosome Disorders
    Terry J. Hassold / Stuart Schwartz

    64 The Practice of Genetics in Clinical Medicine
    Susan Miesfeldt / J. Larry Jameson

    65 Gene Therapy in Clinical Medicine
    Katherine A. High

    PART 4::

    Regenerative Medicine

    66 Stem Cell Biology
    Minoru S. H. Ko

    67 Applications of Stem Cell Biology in Clinical Medicine
    Jack A. Kessler

    68 Hematopoietic Stem Cells
    David T. Scadden / Dan L. Longo

    69 Tissue Engineering
    Jennifer Anderson /Joseph P. Vacanti

    PART 5:: Nutrition

    70 Nutritional Requirements and Dietary Assessment
    Johanna Dwyer

    71 Vitamin and Trace Mineral Deficiency and Excess
    Robert M. Russell / Paolo M. Suter

    72 Malnutrition and Nutritional Assessment
    Douglas C. Heimburger

    73 Enteral and Parenteral Nutrition Therapy
    Bruce R. Bistrian / David F. Driscoll

    74 Biology of Obesity
    Jeffrey S. Flier / Eleftheria Maratos-Flier

    75 Evaluation and Management of Obesity
    Robert F. Kushner

    76 Eating Disorders
    B. Timothy Walsh

    PART 6:: Oncology and Hematology

    Section 1:: Neoplastic Disorders

    77 Approach to the Patient with Cancer
    Dan L. Longo

    78 Prevention and Early Detection of Cancer
    Otis W. Brawley / Barnett S. Kramer

    79 Cancer Genetics
    Pat J. Morin / Jeffrey M. Trent / Francis S. Collins / Bert Vogelstein

    80 Cancer Cell Biology and Angiogenesis
    Robert G. Fenton / Dan L. Longo

    81 Principles of Cancer Treatment
    Edward A. Sausville / Dan L. Longo

    82 Infections in Patients with Cancer
    Robert Finberg

    83 Cancer of the Skin
    Arthur J. Sober / Hensin Tsao / Carl V. Washington

    84 Head and Neck Cancer
    Everett E. Vokes

    85 Neoplasms of the Lung
    John D. Minna / Joan H. Schiller

    86 Breast Cancer
    Marc E. Lippman

    87 Gastrointestinal Tract Center
    Robert J. Mayer

    88 Tumors of the Liver and Biliary Tree
    Brian I. Carr

    89 Pancreatic Cancer
    Yu Jo Chua / David Cunningham

    90 Bladder and Renal Cell Carcinomas
    Howard I. Scher / Robert J. Motzer

    91 Benign and Malignant Diseases of the Prostate
    Howard I. Scher

    92 Testicular Cancer
    Robert J. Motzer / George J. Bosl

    93 Gynecologic Malignancies
    Robert C. Young

    94 Soft Tissue and Bone Sarcomas and Bone Metastases
    Shreyaskumar R. Patel / Robert S. Benjamin

    95 Carcinoma of Unknown Primary
    Gauri R. Varadhachary /James L. Abbruzzese

    96 Paraneoplastic Syndromes:: Endocrinologic/Hematologic
    J. Larry Jameson / Bruce E. Johnson

    97 Paraneoplastic Neurologic Syndromes
    Josep Dalmau / Myrna R. Rosenfeld

    e12 Thymoma
    Dan L. Longo

    e13 Late Consequences of Cancer and Its Treatment
    Michael C. Perry / Dan L. Longo

    Section 2:: Hematopoietic Disorders

    98 Iron Deficiency and Other Hypoproliferative Anemias
    John W. Adamson

    99 Disorders of Hemoglobin
    Edward J. Benz, Jr.

    100 Megaloblastic Anemias
    A. Victor Hoffbrand

    101 Hemolytic Anemias and Anemia Due to Acute Blood Loss
    Lucio Luzzatto

    102 Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes
    Neal S. Young

    103 Polycythemia Vera and Other Myeloproliferative Diseases
    Jerry L. Spivak

    104 Acute and Chronic Myeloid Leukemia
    Meir Wetzler /John C. Byrd / Clara D. Bloomfield

    105 Malignancies of Lymphoid Cells
    Dan L. Longo

    106 Plasma Cell Disorders
    Nikhil C. Munshi / Dan L. Longo / Kenneth C. Anderson

    107 Transfusion Biology and Therapy
    Jeffery S. Dzieczkowski / Kenneth C. Anderson

    108 Hematopoietic Cell Transplantation
    Frederick R. Applebaum

    Section 3:: Disorders of Hemostasis

    109 Disorders of Platelets and Vessel Wall
    Barbara A. Konkle

    110 Coagulation Disorders
    Valder Arruda / Katherine A. High

    111 Venous Thrombosis
    F.R. Rosendaal / H.R. Buller

    112 Antiplatelet, Anticoagulant, and Fibrinolytic Drugs
    Jeffery I. Weitz

    PART 7:: Infectious Diseases

    Section 1:: Basic Considerations in Infectious Diseases

    113 Introduction to Infectious Diseases:: Host-Pathogen Interactions
    Lawrence C. Madoff / Dennis L. Kasper

    114 Molecular Mechanisms of Microbial Pathogenesis
    Gerald B. Pier

    115 Approach to the Acutely Ill Infected Febrile Patient
    Tamar F. Barlam / Dennis L. Kasper

    116 Immunization Principles and Vaccine Use
    Gerald T. Keusch / Kenneth J. Bart / Mark Miller

    117 Health Advice for International Travel
    J.S. Keystone / Phyllis E. Kozarsky

    e14 Laboratory Diagnosis of Infectious Diseases
    Alexander J. McAdam / Andrew B. Onderdonk

    Section 2:: Clinical Syndromes:: Community-Acquired Infections

    118 Infective Endocarditis
    Adolf W. Karchmer

    119 Infections of the Skin, Muscle, and Soft Tissues
    Dennis L. Stevens

    120 Osteomyelitis
    Jeffrey Parsonnet

    121 Intraabdominal Infections and Abscesses
    Miriam J. Baron / Dennis L. Kasper

    122 Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning
    Joan R. Butterton / Stephen B. Calderwood

    123 Clostridium difficile-Associated Disease, Including Pseudomembranous Colitis
    Dale N. Gerding / Stuart Johnson

    124 Sexually Transmitted Infections:: Overview and Clinical Approach
    King K. Holmes

    e15 Infectious Complications of Burns and Bites
    Lawrence C. Madoff / Florencia Pereyra

    Section 3:: Clinical Syndromes:: Health Care-Associated Infections

    125 Health Care-Associated Infections
    Robert A. Weinstein

    126 Infections in Transplant Recipients
    Robert Finberg /Joyce Fingeroth

    Section 4:: Approach to Therapy for Bacterial Diseases

    127 Treatment and Prophylaxis of Bacterial Infections
    Gordon L. Archer / Ronald E. Polk

    Section 5:: Diseases Caused by Gram-Positive Bacteria

    128 Pneumococcal Infections
    Daniel M. Musher

    129 Staphylococcal Infections
    Franklin D. Lowy

    130 Streptococcal and Enterococcal Infections
    Michael R. Wessels

    131 Diphtheria and Other Infections Caused by Corynebacteria and Related Species
    William R. Bishai / John R. Murphy

    132 Infections Caused by Listeria monocytogenes
    Elizabeth L. Hohmann / Daniel A. Portnoy

    133 Tetanus
    Elias Abrutyn

    134 Botulism
    Elias Abrutyn

    135 Gas Gangrene and Other Clostridial Infections
    Dennis L. Kasper /Lawrence C. Madoff

    Section 6:: Diseases Caused by Gram-Negative Bacteria

    136 Meningococcal Infections
    Lee M. Wetzler

    137 Gonococcal Infections
    Sanjay Ram / Peter A. Rice

    138 Moraxella Infections
    Daniel M. Musher

    139 Haemophilus Infections
    Timothy F. Murphy

    140 Infections Due to the HACEK Group and Miscellaneous Gram-Negative Bacteria
    Tamar F. Barlam / Dennis L. Kasper

    141 Legionella Infection
    Miguel Sabria / Victor L. Yu

    142 Pertussis and Other Bordetella Infections
    Scott A. Halperin

    143 Diseases Caused by Gram-Negative Enteric Bacilli
    Thomas A. Russo / James R. Johnson

    144 Helicobacter pylori Infections
    John C. Atherton / Martin J. Blaser

    145 Infections Due to Pseudomonas Species and Related Organisms
    Reuben Ramphal

    146 Salmonellosis
    David A. Pegues / Samuel I. Miller

    147 Shigellosis
    Philippe Sansonetti / Jean Bergounioux

    148 Infections Due to Campylobacter and Related Species
    Martin J. Blaser

    149 Cholera and Other Vibrioses
    Matthew K. Waldor / Gerald T. Keusch

    150 Brucellosis
    Michael J. Corbel / Nicholas J. Beeching

    151 Tularemia
    Richard F. Jacobs / Gordon E. Schutze

    152 Plague and Other Yersinia Infections
    David T. Dennis / Grant L. Campbell

    153 Bartonella Infections, Including Cat-Scratch Disease
    David H. Spach / Emily Darby

    154 Donovanosis
    Gavin Hart

    Section 7:: Miscellaneous Bacterial Infections

    155 Nocardiosis
    Gregory A. Filice

    156 Actinomycosis
    Thomas A. Russo

    157 Infections Due to Mixed Anaerobic Organisms
    Dennis L. Kasper / Ronit Cohen-Poradosu

    Section 8:: Mycobacterial Diseases

    158 Tuberculosis
    Mario C. Raviglione / Richard J. O?Brien

    159 Leprosy (Hansen?s Disease)
    Robert H. Gelber

    160 Nontuberculous Mycobacteria
    C. Fordham von Reyn

    161 Antimycobacterial Agents
    Richard J. Wallace, Jr. / David E. Griffith

    Section 9:: Spirochetal Disease

    162 Syphilis
    Sheila A. Lukehart

    163 Endemic Treponematoses
    Sheila A. Lukehart

    164 Leptospirosis
    Peter Speelman / Rudy Harkskeerl

    165 Relapsing Fever
    David T. Dennis

    166 Lyme Borreliosis
    Allen C. Steere

    Section 10:: Diseases Caused by Rickettsiae, Mycoplasmas, and Chlamydiae

    167 Rickettsial Diseases
    David H. Walker / J. Stephen Dumler / Thomas Marrie

    168 Infections Due to Mycoplasmas
    William M. McCormack

    169 Chlamydial Infections
    Walter E. Stamm

    Section 11:: Viral Diseases:: General Considerations

    170 Medical Virology
    Fred Wang /Elliott Kieff

    171 Antiviral Chemotherapy, Excluding Antiretroviral Drugs
    Lindsey R. Baden / Raphael Dolin

    Section 12:: Infections Due to DNA Viruses

    172 Herpes Simplex Viruses
    Lawrence Corey

    73 Varicella-Zoster Virus Infections
    Richard J. Whitley

    174 Epstein-Barr Virus Infections, Including Infectious Mononucleosis
    Jeffry I. Cohen

    175 Cytomegalovirus and Human Herpesvirus Types 6, 7, and 8
    Martin S. Hirsch

    176 Molluscum Contagiosum, Monkeypox, and Other Poxviruses, Excluding Smallpox Virus
    Fred Wang

    177 Parvovirus Infections
    Kevin E. Brown

    178 Human Papillomavirus Infections
    Richard C. Reichman

    Section 13:: Infections Due to DNA and RNA Respiratory Viruses

    179 Common Viral Respiratory Infections and Severe Acute Respiratory Syndrome (SARS)
    Raphael Dolin

    180 Influenza
    Raphael Dolin

    Section 14:: Infections Due to Human Immunodeficiency Virus and Other Human Retroviruses

    181 The Human Retroviruses
    Dan L. Longo /Anthony S. Fauci

    182 Human Immunodeficiency Virus Disease:: AIDS and Related Disorders
    Anthony S. Fauci / H. Clifford Lane

    Section 15:: Infections Due to RNA Viruses

    183 Viral Gastroenteritis
    Umesh D. Parashar / Roger I. Glass

    184 Enteroviruses and Reoviruses
    Jeffery I. Cohen

    185 Measles (Rubeola)
    Anne Gershon

    186 Rubella (German Measles)
    Anne Gershon

    187 Mumps
    Anne Gershon

    188 Rabies and Other Rhabdovirus Infections
    Alan C. Jackson / Eric C. Johannsen

    189 Infections Caused by Arthropod- and Rodent-Borne Viruses
    Clarence J. Peters

    190 Ebola and Marburg Viruses
    Clarence J. Peters

    Section 16:: Fungal and Algal Infections

    191 Diagnosis and Treatment of Fungal Infections
    John E. Edwards, Jr.

    192 Histoplasmosis
    Chadi A. Hage / L. Joseph Wheat

    193 Coccidioidomycosis
    Neil M. Ampel

    194 Blastomycosis
    Stanley W. Chapman / Donna C. Sullivan

    195 Cryptococcosis
    Arturo Casadevall

    196 Candidiasis
    John E. Edwards, Jr.

    197 Aspergillosis
    David W. Denning

    198 Mucormycosis
    Alan M. Sugar

    199 Miscellaneous Mycoses and Algal Infections
    Stanley W. Chapman / Donna C. Sullivan

    200 Pneumocystis Infection
    A. Geroge Smulian /Peter D. Walzer

    Section 17:: Protozoal and Helminthic Infections:: General Considerations

    e16 Laboratory Diagnosis of Parasitic Infections
    Sharon L. Reed / Charles E. Davis

    201 Agents Used to Treat Parasitic Infections
    Thomas A. Moore

    e17 Pharmacology of Agents Used to Treat Parasitic Infections
    Thomas A. Moore

    Section 18:: Protozoal Infections

    202 Amebiasis and Infection with Free-Living Amebas
    Sharon L. Reed

    203 Malaria
    Nicholas J. White / Joel G. Breman

    204 Babesiosis
    Jeffry Gelfand / Edouard Vannier

    e18 Atlas of Blood Smears of Malaria and Babesiosis
    Nicholas J. White / Joel G. Breman

    205 Leishmaniasis
    Barbara L. Herwaldt

    206 Trypanosomiasis
    Louis V. Kirchhoff

    207 Toxoplasma Infections
    Lloyd H. Kasper

    208 Protozoal Intestinal Infections and Trichomoniasis
    Peter F. Weller

    Section 19:: Helminthic Infections

    209 Trichinella and Other Tissue Nematodes
    Peter F. Weller

    210 Intestinal Nematodes
    Peter F. Weller /Thomas B. Nutman

    211 Filarial and Related Infections
    Thomas B. Nutman / Peter F. Weller

    212 Schistosomiasis and Other Trematode Infections
    Adel A.F. Mahmoud

    213 Cestodes
    A. Clinton White, Jr. / Peter F. Weller

    PART 8:: Bioterrorism and Clinical Medicine

    214 Microbial Bioterrorism
    H. Clifford Lane / Anthony S. Fauci

    215 Chemical Bioterrorism
    Charles G. Hurst / Jonathan Newmark / James A. Romano, Jr.

    216 Radiation Bioterrorism
    Zelig A. Tochner / Eli Glatstein

    PART 9:: Disorders of the Cardiovascular System

    Section 1:: Introduction to Cardiovascular Disorders

    217 Basic Biology of the Cardiovascular System
    Joseph Loscalzo / Peter Libby / Eugene Braunwald

    218 Epidemiology of Cardiovascular Disease
    Thomas A. Gaziano / J. Michael Gaziano

    219 Approach to the Patient with Possible Cardiovascular Disease
    Eugene Braunwald

    Section 2:: Diagnosis of Cardiovascular Disorders

    220 Physical Examination of the Cardiovascular System
    Robert A. O?Rourke /Eugene Braunwald

    221 Electrocardiography
    Ary L. Goldberger

    e19 Atlas of Electrocardiography
    Ary L. Goldberger

    222 Noninvasive Cardiac Imaging:: Echocardiography, Nuclear Cardiology, and MRI/CT Imaging
    Rick A. Nishimura / Raymond J. Gibbons / James F. Glockner /A. Jamil Tajik

    e20 Atlas of Noninvasive Cardiac Imaging
    Rick A. Nishimura / Raymond J. Gibbons / James F. Glockner / A. Jamil Tajik

    223 Diagnostic Cardiac Catheterization and Angiography
    Donald S. Baim

    Section 3:: Disorders of Rhythm

    224 Principles of Electrophysiology
    Gordon F. Tomaselli

    225 The Bradyarrhythmias
    Gordon F. Tomaselli

    226 The Tachyarrhythmias
    Francis Marchlinksi

    e21 Atlas of Cardiac Arrhythmias
    Ary L. Goldberger

    Section 4:: Disorders of the Heart

    227 Heart Failure and Cor Pulmonale
    Douglas L. Mann

    228 Cardiac Transplantation and Prolonged Assisted Circulation
    Sharon A. Hunt

    229 Congenital Heart Disease in the Adult
    John S. Child

    230 Valvular Heart Disease
    Patrick O?Gara / Eugene Braunwald

    231 Cardiomyopathy and Myocarditis
    Joshua Wynne / Eugene Braunwald

    232 Pericardial Disease
    Eugene Braunwald

    233 Tumors and Trauma of the Heart
    Eric H. Awtry / Wilson S. Colucci

    234 Cardiac Manifestations of Systemic Disease
    Eric H. Awtry / Wilson S. Colucci

    Section 5:: Vascular Disease

    235 The Pathogenesis, Prevention, and Treatment of Atherosclerosis
    Peter Libby

    e22 Atlas of Atherosclerosis
    Peter Libby

    236 The Metabolic Syndrome
    Robert H. Eckel

    237 Ischemic Heart Disease
    Elliott M. Antman / Andrew P. Selwyn/ Eugene Braunwald / Joseph Loscalzo

    238 Unstable Angina and Non-ST-Elevation Myocardial Infarction
    Christopher P. Cannon / Eugene Braunwald

    239 ST-Segment Elevation Myocardial Infarction
    Elliott M. Antman / Eugene Braunwald

    240 Percutaneous Coronary Intervention
    Donald S. Baim

    e23 Atlas of Percutaneous Revascularization
    Donald S. Baim

    241 Hypertensive Vascular Disease
    Ted A. Kotchen

    242 Diseases of the Aorta
    Mark A. Creager / Joseph Loscalzo

    243 Vascular Diseases of the Extremities
    Mark A. Creager / Joseph Loscalzo

    244 Pulmonary Hypertension
    Stuart Rich

    PART 10:: Disorders of the Respiratory System

    Section 1:: Diagnosis of Respiratory Disorders

    245 Approach to the Patient with Disease of the Respiratory System
    David A. Lipson / Steven E. Weinberger

    246 Disturbances of Respiratory Function
    Steven E. Weinberger /Ilene M. Rosen

    247 Diagnostic Procedures in Respiratory Diseases
    Scott Manaker / Steven E. Weinberger

    e24 Atlas of Chest Imaging
    Patricia A. Kritek / John J. Reilly, Jr.

    248 Asthma
    Peter J. Barnes

    249 Hypersensitivity Pneumonitis and Pulmonary Infiltrates with Eosinophilia
    Joel N. Kline / Gary W. Hunninghake

    250 Environmental Lung Disease
    Frank E. Speizer / John R. Balmes

    251 Pneumonia
    Lionel A. Mandell / Richard Wunderink

    252 Bronchiectasis and Lung Abscess
    Gregory Tino / Steven E. Weinberger

    253 Cystic Fibrosis
    Richard C. Boucher

    254 Chronic Obstructive Pulmonary Disease
    John J. Reilly, Jr. / Edwin K. Silverman / Steven D. Shapiro

    255 Interstitial Lung Diseases
    Talmadge E. King, Jr.

    256 Deep Venous Thrombosis and Pulmonary Thromboembolism
    Samuel Z. Goldhaber

    257 Disorders of the Pleura and Mediastinum
    Richard W. Light

    258 Disorders of Ventilation
    Eliot A. Phillipson

    259 Sleep Apnea
    Neil J. Douglas

    260 Lung Transplantation
    Elbert P. Trulock

    PART 11:: Critical Care Medicine

    Section 1:: Respiratory Critical Care

    261 Principles of Critical Care Medicine
    John P. Kress / Jesse B. Hall

    262 Acute Respiratory Distress Syndrome
    Bruce D. Levy / Steve D. Shapiro

    263 Mechanical Ventilatory Support
    Edward P. Ingenito

    Section 2:: Shock and Cardiac Arrest

    264 Approach to the Patient with Shock
    Ronald V. Maier

    265 Severe Sepsis and Septic Shock
    Robert S. Munford

    266 Cardiogenic Shock and Pulmonary Edema
    Judith S. Hochman / David H. Ingbar

    267 Cardiovascular Collapse, Cardiac Arrest, and Sudden Cardiac Death
    Robert J. Myerberg / Agustin Castellanos

    Section 3:: Neurologic Critical Care

    268 Coma
    Allan H. Ropper

    269 Neurologic Critical Care, Including Hypoxic-Ischemic Encephalopathy and Subarachnoid Hemorrhage
    J. Claude Hemphill, III / Wade S. Smith

    Section 4:: Oncologic Emergencies

    270 Oncologic Emergencies
    Rasim Gucalp / Janice P. Dutcher

    PART 12:: Disorders of the Kidney and Urinary Tract

    271 Cellular and Molecular Biology of the Kidney
    Alfred L. George, Jr. / Eric G. Neilson

    272 Adaptation of the Kidney to Renal Injury
    Raymond C. Harris / Eric G. Neilson

    273 Acute Renal Failure
    Kathleen D. Liu / Glenn M. Chertow

    274 Chronic Kidney Disease
    Joanne M. Bargman / Karl Skorecki

    275 Dialysis in the Treatment of Renal Failure
    Kathleen D. Liu / Glenn M. Chertow

    276 Transplantation in the Treatment of Renal Failure
    Charles B. Carpenter / Edgar L. Milford / Mohamed H. Sayegh

    277 Glomerular Diseases
    Julia B. Lewis / Eric G. Neilson

    278 Polycystic Kidney Disease and Other Inherited Tubular Disorders
    David J. Salant / Parul S. Patel

    279 Tubulointerstitial Diseases of the Kidney
    Alan S. L. Yu / Barry M. Brenner

    280 Vascular Injury to the Kidney
    Kamal F. Badr / Barry M. Brenner

    281 Nephrolithiasis
    John R. Asplin / Fredric L. Coe / Murray J. Favus

    282 Urinary Tract Infections, Pyelonephritis, and Prostatitis
    Walter E. Stamm

    283 Urinary Tract Obstruction
    Julian L. Seifter / Barry M. Brenner

    PART 13:: Disorders of the Gastrointestinal System

    Section 1:: Disorders of the Alimentary Tract

    284 Approach to the Patient with Gastrointestinal Disease
    William L. Hasler / Chung Owyang

    285 Gastrointestinal Endoscopy
    Louis Michel Wong-Kee-Song / Mark Topazian

    e25 Video Atlas of Gastrointestinal Endoscopy
    Louis Michel Wong-Kee-Song / Mark Topazian

    286 Diseases of the Esophagus
    Raj. K. Goyal

    287 Peptic Ulcer Disease and Related Disorders
    John Del Valle

    288 Disorders of Absorption
    Henry J. Binder

    289 Inflammatory Bowel Disease
    Sonia Friedman / Richard S. Blumberg

    290 Irritable Bowel Syndrome
    Chung Owyang

    291 Diverticular Disease and Common Anorectal Disorders
    Susan L. Gearhart

    292 Mesenteric Vascular Insufficiency
    Susan L. Gearhart

    293 Acute Intestinal Obstruction
    Susan L. Gearhart / William Silen

    294 Acute Appendicitis and Peritonitis
    Susan L. Gearhart / William Silen

    Section 2:: Liver and Biliary Tract Disease

    295 Approach to the Patient with Liver Disease
    Marc Ghany /Jay H. Hoofnagle

    296 Evaluation of Liver Function
    Daniel S. Pratt / Marshall M. Kaplan

    297 The Hyperbilirubinemias
    Allan W. Wolkoff

    298 Acute Viral Hepatitis
    Jules L. Dienstag

    299 Toxic and Drug-Induced Hepatitis
    Jules L. Dienstag

    300 Chronic Hepatitis
    Jules L. Dienstag

    301 Alcoholic Liver Disease
    Mark E. Mailliard / Michael F. Sorrell

    302 Cirrhosis and Its Complications
    Bruce R. Bacon

    e26 Atlas of Liver Biopsies
    Jules L. Dienstag / Atul K. Bhan

    303 Genetic, Metabolic, and Infiltrative Diseases Affecting the Liver
    Bruce R. Bacon

    304 Liver Transplantation
    Jules L. Dienstag /Raymond T. Chung

    305 Diseases of the Gallbladder and Bile Ducts
    Norton J. Greenberger / Gustav Paumgartner

    Section 3:: Disorders of the Pancreas

    306 Approach to the Patient with Pancreatic Disease
    Phillip P. Toskes / Norton J. Greenberger

    307 Acute and Chronic Pancreatitis
    Norton J. Greenberger / Phillip P. Toskes

    PART 14:: Disorders of the Immune System, Connective Tissue, and Joints

    Section 1:: The Immune System in Health and Disease

    308 Introduction to the Immune System
    Barton F. Haynes / Kelly A. Soderberg / Anthony S. Fauci

    309 The Major Histocompatability Complex
    Gerald T. Nepom

    310 Primary Immune Deficiency Diseases
    Max D. Cooper / Harry W. Schroeder, Jr.

    e27 Primary Immunodeficiencies Associated with or Secondary to Other Diseases
    Max D. Cooper / Harry W. Schroeder, Jr.

    Section 2:: Disorders of Immune-Mediated Injury

    311 Allergies, Anaphylaxis, and Systemic Mastocytosis
    K. Frank Austen

    312 Autoimmunity and Autoimmune Diseases
    Peter E. Lipsky / Betty Diamond

    313 Systemic Lupus Erythematosus
    Bevra Hannahs Hahn

    314 Rheumatoid Arthritis
    Peter E. Lipsky

    315 Acute Rheumatoid Fever
    Jonathan R. Carapetis

    316 Systemic Sclerosis (Scleroderma) and Related Disorders
    John Varga

    317 Sjogren?s Syndrome
    Haralampos M. Moutsopoulos

    318 The Spondyloarthritides
    Joel D. Taurog

    319 The Vasculitis Syndromes
    Carol A. Langford / Anthony S. Fauci

    e28 Atlas of Clinical Imaging of the Vasculitic Diseases
    Carol A. Langford / Anthony S. Fauci

    320 Behcet?s Syndrome
    Haralampos M. Moutsopoulos

    321 Relapsing Polychondritis
    Carol A. Langford /Bruce C. Gilliland

    322 Sarcoidosis
    Robert P. Baughman /Elyse E. Lower

    323 Familial Mediterranean Fever
    Daniel L. Kastner

    324 Amyloidosis
    David C. Seldin / Martha Skinner

    Section 3:: Disorders of the Joints and Adjacent Tissues

    325 Approach to Articular and Musculoskeletal Disorders
    John J. Cush / Peter E. Lipsky

    326 Osteoarthritis
    David T. Felson

    327 Gout and Other Crystal Arthropathies
    H. Ralph Schumacher / Lan X. Chen

    328 Infectious Arthritis
    Lawrence C. Madoff

    329 Fibromyalgia
    Carol A. Langford /Bruce C. Gilliland

    330 Arthritis Associated with Systemic Disease and Other Arthritides
    Carol A. Langford / Bruce C. Gilliland

    331 Periarticular Disorders of the Extremities
    Carol A. Langford / Bruce C. Gilliland

    PART 15:: Endocrinology and Metabolism

    Section 1:: Endocrinology

    332 Principles of Endocrinology
    J. Larry Jameson

    333 Disorders of the Anterior Pituitary and Hypothalamus
    Shlomo Melmed / J. Larry Jameson

    334 Disorders of the Neurohypophysis
    Gary L. Robertson

    335 Disorders of the Thyroid Gland
    J. Larry Jameson / Anthony P. Weetman

    336 Disorders of the Adrenal Cortex
    Gordon H. Williams / Robert G. Dluhy

    337 Pheochromocytoma
    Hartmut P.H. Neumann

    338 Diabetes Mellitus
    Alvin C. Powers

    339 Hypoglycemia
    Philip E. Cryer

    340 Disorders of the Testes and the Male Reproductive System
    Shalender Bhasin / J. Larry Jameson

    341 The Female Reproductive System:: Infertility and Contraception
    Janet E. Hall

    342 The Menopause Transition and Postmenopausal Hormone Therapy
    JoAnn E. Manson /Shari S. Bassuk

    343 Disorders of Sex Development
    John C. Achermann / J. Larry Jameson

    344 Endocrine Tumors of the Gastrointestinal Tract and Pancreas
    Robert T. Jensen

    345 Disorders Affecting Multiple Endocrine Systems
    Camilo Jimenez / Robert F. Gagel

    Section 2:: Disorders of Bone and Mineral Metabolism

    346 Bone and Mineral Metabolism in Health and Disease
    F. Richard Bringhurst / Marie B. Demay / Stephen M. Krane / Henry M. Kronenberg

    347 Diseases of the Parathyroid Gland and Other Hyper- and Hypocalcemic Disorders
    John T. Potts, Jr.

    348 Osteoporosis
    Robert Lindsay / Felicia Cosman

    349 Paget Disease and Other Dysplasias of Bone
    Murray J. Favus /Tamara J. Vokes

    Section 3:: Disorders of Intermediary Metabolism

    350 Disorders of Lipoprotein Metabolism
    Daniel J. Rader / Helen H. Hobbs

    351 Hemochromatosis
    Lawrie W. Powell

    352 The Porphyrias
    Robert J. Desnick / Kenneth H. Astrin

    353 Disorders of Purine and Pyrimidine Metabolism
    Robert L. Wortmann

    354 Wilson Disease
    George J. Brewer

    355 Lysosomal Storage Disease
    Robert J. Hopkin / Gregory A. Grabowski

    356 Glycogen Storage Diseases and Other Inherited Disorders of Carbohydrate Metabolism
    Yuan-Tsong Chen

    357 Heritable Disorders of Connective Tissue
    Darwin J. Prockop / Malwina Czarny-Ratajczak

    358 Inherited Disoders of Amino Acid Metabolism in Adults
    Nicola Longo

    359 Inherited Defects of Membrane Transport
    Nicola Longo

    e29 Atlas of Clinical Manifestations of Metabolic Diseases
    J. Larry Jameson

    PART 16:: Neurologic Disorders

    Section 1:: Diagnosis of Neurologic Disorders

    360 Mechanisms of Neurologic Disorders
    Stephen L. Hauser / M. Flint Beal

    361 Approach to the Patient with Neurologic Disease
    Daniel H. Lowenstein / Joseph B. Martin / Stephen L. Hauser

    362 Neuroimaging in Neurologic Disorders
    William P. Dillon

    e30 Atlas of Neuroimaging
    Andre Furtado / William P. Dillon

    e31 Electrodiagnostic Studies of Nervous System Disorders:: EEG, Evoked Potentials, and EMG
    Michael J. Aminoff

    e32 Technique of Lumbar Puncture
    Elizabeth Robbins / Stephen L. Hauser

    Section 2:: Diseases of the Central Nervous System

    363 Seizures and Epilepsy
    Daniel H. Lowenstein

    364 Cerebrovascular Diseases
    Wade S. Smith / Joey D. English / S. Claiborne Johnston

    365 Dementia
    Thomas D. Bird / Bruce L. Miller

    366 Parkinson?s Disease and Other Extrapyramidal Movement Disorders
    Mahlon R. DeLong / Jorge L. Juncos

    367 Hyperkinetic Movement Disorders
    C. Warren Olanow

    368 Ataxic Disorders
    Roger N. Rosenberg

    369 Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases
    Robert H. Brown, Jr.

    370 Disorders of the Autonomic Nervous System
    Phillip A. Low / John W. Engstrom

    371 Trigeminal Neuralgia, Bell?s Palsy, and Other Cranial Nerve Disorders
    M. Flint Beal / Stephen L. Hauser

    372 Diseases of the Spinal Cord
    Stephen L. Hauser / Allan H. Ropper

    373 Concussion and Other Head Injuries
    Allan H. Ropper

    374 Primary and Metastatic Tumors of the Nervous System
    Stephen M. Sagar / Mark A. Israel

    375 Multiple Sclerosis and Other Demyelinating Diseases
    Stephen L. Hauser / Douglas S. Goodin

    376 Meningitis, Encephalitis, Brain Abscess,and Empyema
    Karen L. Roos / Kenneth L. Tyler

    377 Chronic and Recurrent Meningitis
    Walter J. Koroshetz / Morton N. Swartz

    378 Prion Diseases
    Stanley B. Prusiner / Bruce L. Miller

    Section 3:: Nerve and Muscle Disorders

    379 Peripheral Neuropathy
    Vinay Chaudhry

    380 Guillain-Barre Syndrome and Other Immune-Mediated Neuropathies
    Steven L. Hauser / Arthur K. Asbury

    381 Myasthenia Gravis and Other Diseases of the Neuromuscular Junction
    Daniel B. Drachman

    382 Muscular Dystrophies and Other Muscle Diseases
    Robert H. Brown, Jr. / Anthony A. Amato / Jerry R. Mendell

    383 Polymyositis, Dermatomyositis, and Inclusion Body Myositis
    Marinos C. Dalakas

    e33 Special Issues in Inpatient Neurologic Consultation
    S. Andrew Josephson / Martin A. Samuels

    Section 4:: Chronic Fatigue Syndrome

    384 Chronic Fatigue Syndrome
    Stephen E. Straus

    Section 5:: Psychiatric Disorders

    385 Biology of Psychiatric Disorders
    Steven E. Hyman / Eric Kandel

    386 Mental Disorders
    Victor I. Reus

    Section 6:: Alcoholism and Drug Dependency

    387 Alcohol and Alcoholism
    Marc A. Schuckit

    388 Opioid Drug Abuse and Dependence
    Mark A. Schuckit

    389 Cocaine and Other Commonly Abused Drugs
    Jack H. Mendelson / Nancy K. Mello

    390 Nicotine Addiction
    David M. Burns

    PART 17:: Poisoning, Drug Overdose, and Envenomation

    e34 Heavy Metal Poisoning
    Howard Hu

    e35 Poisoning and Drug Overdosage
    Christopher H. Linden / Michael J. Burns / Mark B. Mycyk

    391 Disorders Caused by Reptile Bites and Marine Animal Exposures
    Paul S. Auerbach / Robert L. Norris

    392 Ectoparasite Infestations and Arthropod Bites and Stings
    Richard J. Pollack / James H. Maguire

    PART 18:: e-Chapters from International Advisory Editors

    e36 Pulmonary Biomarkers in COPD
    Peter J. Barnes

    e37 Chagas? Disease:: Advances in Diagnosis and Management
    Andrei C. Sposito / Jose A.F. Ramires

    e38 The Polypill
    K. Srinath Reddy / Nitish Naik / Ambuj Roy

    e39 Mitochondrial DNA and Heritable Traits and Diseases
    Karl Skorecki / Hanna Mandel

    Appendix:: Laboratory Values of Clinical Importance
    Alexander Kratz / Michael A. Pesce / Daniel J. Fink

    Index

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