In this issue of Gastrointestinal Endoscopy Clinics of North America, guest editor Dr. Patrick Pfau brings his considerable expertise to the topic of Gastrointestinal Bleeding. Top experts in the field cover a broad range of topics on the diagnosis and treatment of both upper and lower gastrointestinal bleeding with a concentration on endoscopic intervention. This issue discusses the preparation of the patient with a GI bleed even before endoscopy is performed, and provides extensive coverage of the latest data and technology for variceal and non-variceal upper GI tract bleeding, small bowel/occult, and lower GI and colonic bleeding.