As a family physician in the town of Bedford, you see a lot of interesting clinical cases, especially among the influential Savoy and Sampson families. When Nick Sampson disappears and a body turns up with connections to Nick, you are drawn into the case. As you are challenged to use an evidence-based approach in managing the wide variety of clinical cases you encounter in Bedford, the cases in turn provide evidence for solving the murder mystery. At once a thrilling, interactive mystery novel and a wonderful guide for incorporating evidence-based medicine into practice, The Bedford Murder is unlike any medical book you will ever read.
FAMILY TREE AND CHARACTER LIST Prelude Celias Distress (Diabetes Mellitus) -Intensity of glucose control in diabetes -Anxiety, insomnia, and benzodiazepines -Affect of stress on glucose levels
Joannes Fear (Pregnancy) -Vaginal birth after cesarean section -Bacterial vaginosis in pregnancy -Asymptomatic bacteriuria in pregnancy
Alexanders Secret (Hypertension) -Thiazides in hypertension -Biochemical monitoring when taking statin drugs -Calculating cardiovascular risk -When is ramipril Indicated? -Effect of life stress on blood pressure readings in the office -Smoking cessation counseling during times of life Nancys Dilemma (Oral Contraceptives) -Third generation progestins and risk of thrombosis -Prevalence of asymptomatic vaginal infection Pierres Lie (Ankle Injury) -Usefulness of Ottawa ankle rules -Microorganisms in cellulitis from a rusty nail Cecil Starkes (Hematuria) -Likelihood of pathology with asymptomatic hematuria -Usefulness of ultrasound in asymptomatic hermaturia
INTERLUDE 1 (Bracken Library, Kingston) Beatrices Grief (Hypothyroidism) -Effect of excess thyroid replacement on cardiovascular risk -Predictors of abnormal grief reactions Aunt Joans Rumor (Congestive Heart Failure) -Adding and ACE to well controlled CHF -Predictors of 5 year outcome in CHF
Fitz (Ischemic Heart Disease) -Target blood pressures in high-risk coronary artery disease -Target lipid levels in high-risk coronary artery disease
Cecilias Gratitude (Diabetes Mellitus) -Blood pressure control in diabetes mellitus.
Alexanders Quest (Hypertension) -Relative importance of cholesterol and Triglycerides on cardiovascular diasease
Joannes Keys (Pregnancy) -Risk of vitamin A in pregnancy
John Hagarty (Tennis Elbow) -Effectiveness of local corticosteroid injection in tennis elbow.
INTERLUME 2(The Bedford Family Medicine Clinic) Dr. Sharpeís Dilemma (Gonorrhea) -Progression of asymptomatic gonorrhea -Concurrence of HIV and hepatitis C with gonorrhea
Fitzs Worse Fear (Angina) -Prognosis with angina two years post coronary artery bypass surgery
Roberts Connections (Testicular Lump) -Prognostic features of a testicular lump -Usefulness of ultrasound in diagnosing a testicular lump
Gemma and Her Dad (UTI and Color Blindness) -Accuracy of urine nitrates in correctly diagnosing UTI -Adhesive urine specimen collectors in children -Need to investigate children with UTIs -Does color blindness affect ability to drive?
Simon Werston ( Gastro-Esophageal Reflux) -Barium studies compared to endoscopy in GERD -Likelihood of malignancy in GERD if no alarm features -Prokinetic agents without serious side effects
INTERLUDE3 (The Police Station in Toronto) Jane Harris (Osteoarthritis of the Hip) -Success rate and complication rate of total hip replacement
Mary Collier (COPD) -Use of steroids and theophylline in COPD
Leonard Nelson (Color Blindness) -Usefulness of Ishihara charts in diagnosing color blindness
Afterlude Appendix 1:: Understanding the Evidence Tables Appendix 2:: Glossary of Terms References
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