This issue of MRI Clinics of North America focuses on The Gut in MRI:: From the Upper to the Lower Digestive Tract, and is edited by Dr. Andrea Laghi. Articles will include:: Esophagus and stomach:: Is there a role for MRI?; MR of the small bowel:: How to do it; MR in Crohns Disease:: Diagnosis, disease burden and classification; MR in Crohns Disease:: Imaging biomarkers in assessing response to therapy; MR of malabsorption syndromes, vasculitis, and other uncommon diseases; MR of small bowel tumors; MR enema of the colon in the diagnosis of recto-sigmoid endometriosis; Rectal cancer:: Staging; Rectal cancer:: Assessing response to neoadjuvant therapy; MR of anal and peri-anal tumors; MR of perianal fistulas; and more!