Year Book of Medicine 2018

Section 1:: Cardiology
1. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease
2. System of Care for Patients with ST-segment Elevation Myocardial Infarction in India:: The Tamil Nadu-ST-segment Elevation Myocardial Infarction Program
3. Predictors of Death in Contemporary Adult Patients with Eisenmenger Syndrome:: A Multicenter Study
4. Midterm Results of Tetralogy of Fallot with Absent Pulmonary Valve
5. Meta-analysis of the Impact of Intervention versus Symptom-driven Management in Asymptomatic Severe Aortic Stenosis
6. Prevalence and Clinical Manifestations of Primary Aldosteronism Encountered in Primary Care Practice
7. Heart Failure with Preserved, Borderline, and Reduced Ejection Fraction-5-year Outcomes
8. Angiotensin-converting Enzyme Inhibitors and Angiotensin Receptor Blockers in High Vascular Risk
9. Trends in Use of High-intensity Statin Therapy after Myocardial Infarction, 2011 to 2014
10. Trend in Prevalence of Coronary Artery Disease and Risk Factors Over Two Decades in Rural Punjab
11. Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation
12. Implant and Midterm Outcomes of the Subcutaneous Implantable Cardioverter-Defibrillator Registry:: The EFFORTLESS Study
13. Maternal and Fetal Outcomes of Anticoagulation in Pregnant Women with Mechanical Heart Valves
14. Diuretic Treatment in Heart Failure
15. Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease
16. Oxygen Therapy in Suspected Myocardial Infarction
17. Optimal Timing of an Invasive Strategy in Patients with Non-ST Elevation Acute Coronary Syndrome:: A Meta-analysis of Randomized Trials
18. Fruits, Vegetables, and Legume Intake and Cardiovascular Disease and Deaths in 18 Countries (PURE):: A Prospective Cohort Study
19. Global Mortality Variations in Patients with Heart Failure:: Results from the International Congestive Heart Failure (INTER-CHF) Prospective Cohort Study
20. 3-Year Clinical Outcomes with Everolimus-eluting Bioresorbable Coronary Scaffolds-The ABSORB III Trial
Section 2:: Chest and Critical Care
1. The Effects of Atorvastatin on Inflammatory Responses and Mortality in Septic Shock:: A Single-center, Randomized Controlled Trial
2. Prevalence and Etiological Profile of Chronic Obstructive Pulmonary Disease in Nonsmokers
3. Pulmonary Rehabilitation in Patients with Interstitial Lung Diseases in an Outpatient Setting:: A Randomized Controlled Trial
4. Correlation of Cutaneous Sensitivity and Cytokine Response in Children with Asthma
5. Clinical Profile and Treatment Outcome of Drug-resistant Tuberculosis Patients of Western Maharashtra, India
6. Prevalence of Aspergillus Hypersensitivity and Allergic Bronchopulmonary Aspergillosis in Patients with Bronchial Asthma at a Tertiary Care Center in North India
7. The Effect of Diabetes Control Status on Treatment Response in Pulmonary Tuberculosis:: A Prospective Study
8. Efficacy and Safety of Glycopyrrolate/Formoterol Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Patients With COPD
9. Use of Mycophenolate Mofetil or Azathioprine for the Management of Chronic Hypersensitivity Pneumonitis
10. Early Computed Tomography Modifications Following Bronchial Thermoplasty in Patients with Severe Asthma
11. Nintedanib in Patients with Idiopathic Pulmonary Fibrosis and Preserved Lung Volume
12. Severe and Difficult-to-treat Asthma in Adults
13. Acute Respiratory Distress Syndrome
14. Evaluation of a Rapid Molecular Drug-susceptibility Test for Tuberculosis
15. Effect of Azithromycin on Asthma Exacerbations and Quality of Life in Adults with Persistent Uncontrolled Asthma (AMAZES):: A Randomised, Double-blind, Placebo-controlled Trial
16. Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease
17. Tiotropium in Early-stage Chronic Obstructive Pulmonary Disease
18. Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism
19. Should Recommendations about Starting Inhaled Corticosteroid Treatment for Mild Asthma Be Based on Symptom Frequency:: A Post-hoc Efficacy Analysis of the START Study
Section 3:: Diabetes and Metabolic Disorders
1. 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease during Pregnancy and the Postpartum
2. A Systematic Review of Known Interventions for the Treatment of Chronic Non-hypovolaemic Hypotonic Hyponatraemia and a Meta-analysis of the Vaptans
3. Bariatric Surgery versus Intensive Medical Therapy for Diabetes-5?year Outcomes
4. Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
5. Clinical Efficacy and Safety of Achieving Very Low LDL-cholesterol Concentrations with the PCSK9 Inhibitor Evolocumab:: A Prespecified Secondary Analysis of the FOURIER trial
6. Clinical Outcomes of Metformin Use in Populations with Chronic Kidney Disease, Congestive Heart Failure, or Chronic Liver Disease:: A Systematic Review
7. Cardiovascular Mortality and Morbidity in Patients with Type 2 Diabetes following Initiation of Sodium-glucose Co-transporter-2 Inhibitors versus Other Glucose-lowering Drugs (CVD-REAL Nordic):: A Multinational Observational Analysis
8. Diabetic Foot Ulcers and Their Recurrence
9. Primary Care-led Weight Management for Remission of Type 2 Diabetes (DiRECT):: An Open-label, Cluster-randomised Trial
10. Effect of Oral versus Intramuscular Vitamin D Replacement in Apparently Healthy Adults with Vitamin D Deficiency
11. Electrolyte Disturbances in Patients with Chronic Alcohol-use Disorder
12. Hashimotos Thyroiditis:: Relative Recurrence Risk Ratio and Implications for Screening of First Degree Relatives
13. High Prevalence of Hypovitaminosis D in Patients Presenting with Proximal Muscle Weakness:: A Sub-Himalayan Study
14. Liraglutide and Renal Outcomes in Type 2 Diabetes
15. Mortality Rates are Lower in SIAD, than in Hypervolemic or Hypovolemic Hyponatremia:: Results of a Prospective Observational Study
16. Myopathy in Patients Taking Atorvastatin:: A Pilot Study
17. Prevalence of Diabetes and Prediabetes in 15 States of India:: Results from the ICMR-INDIAB Population-based Cross-sectional Study
18. Serum Vitamin B12 Levels in Type 2 Diabetes Patients on Metformin Compared to those Never on Metformin:: A Cross?sectional Study
19. Sheehans Syndrome-The Most Common Cause of Panhypopituitarism at Moderate Altitude:: A Sub-Himalayan Study
20. The Association between Subclinical Thyroid Dysfunction and Dementia:: The Health, Aging, and Body Composition (Health ABC) Study
21. The Lipid-lowering Effect of Levothyroxine in Patients with Subclinical Hypothyroidism:: A Systematic Review and Meta-analysis of Randomized Controlled Trials 93
Section 4:: Gastroenterology/Hepatology
1. A Comparison of the Rate of Gastrointestinal Bleeding in Patients Taking Non-vitamin K Antagonist Oral Anticoagulants or Warfarin
2. Comparing Intravenous and Oral Proton Pump Inhibitor Therapy for Bleeding Peptic Ulcers Following Endoscopic Management:: A Systematic Review and Meta-analysis
3. Complications of Proton Pump Inhibitor Therapy
4. Single Center Experience of a New Endoscopic Clip in Managing Nonvariceal Upper Gastrointestinal Bleeding
5. ACG and CAG Clinical Guideline:: Management of Dyspepsia
6. A Randomised Trial of Endoscopic Submucosal Dissection Versus Endoscopic Mucosal Resection for Early Barretts Neoplasia
7. Peroral Endoscopic Myotomy in Treatment-na?ve Achalasia Patients Versus Prior Treatment Failure Cases
8. Endoscopic Step-up Approach Using a Dedicated Biflanged Metal Stent Reduces the Need for Direct Necrosectomy in Walled-off Necrosis (with Videos)
9. Association between Screen-Detected Gallstone Disease and Cancer in a Cohort Study
10. Efficacy of Pancreatic Enzyme Replacement Therapy in Chronic Pancreatitis:: Systematic Review and Meta-analysis
11. Endoscopic and Clinical Responses to Antitubercular Therapy Can Differentiate Intestinal Tuberculosis from Crohns Disease
12. Risk of Colorectal cancer in Asian Patients with Ulcerative Colitis:: A Systemic Review and Meta-analysis
13. Global Prevalence of Celiac Disease:: Systematic Review and Meta-analysis
14. Targeting the Gut-liver Axis in Liver Disease
15. Healthy Donor Fecal Microbiota Transplantation in Steroid-ineligible Severe Alcoholic Hepatitis:: A Pilot Study
16. Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis
17. Long-term Outcomes of Entecavir Monotherapy for Chronic Hepatitis B after Liver Transplantation:: Results Up to 8 Years
18. Liver Transplantation in the Most Severely Ill Cirrhotic Patients:: A Multicenter Study in Acute-on-chronic Liver Failure Grade 3
19. Successful Treatment of Chronic Hepatitis C Infection with Directly Acting Antivirals in Renal Transplant Recipients
20. L-ornithine L-aspartate in Bouts of Overt Hepatic Encephalopathy
Section 5:: Infectious Diseases, HIV, and TB
1. New Drugs and Perspectives for New Antituberculosis Regimens
2. Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children:: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)
3. Point of care Diagnostics for Tuberculosis
4. Index-TB Guidelines:: Guidelines on Extrapulmonary Tuberculosis for India
5. Latent Tuberculosis Infection:: Updated and Consolidated Guidelines for Programmatic Management
6. Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa
7. HIV-TB Coinfection among 57 Million Pregnant Women, Obstetric Complications, Alcohol Use, Drug Abuse, and Depression
8. Survival of HIV-positive Patients Starting Antiretroviral Therapy between 1996 and 2013:: A Collaborative Analysis of Cohort Studies
9. Prevalence of Opportunistic Infections and Causes of Death among Hospitalized HIV-infected Patients in Sichuan, China
10. An Overview of New Delhi Metallo-beta Lactamase-1 and Extended Spectrum Beta Lactamase Producing Bacteria:: Need for an Alternate
11. The Antibiotic Resistance Crisis, with a Focus on the United States
12. Cardiovascular Complications and Short-term Mortality Risk in Community-acquired Pneumonia
13. Tropical Fevers in Indian Intensive Care Units:: A Prospective Multicenter Study
14. Zika Virus Infection and Associated Neurologic Disorders in Brazil
15. Post-Babesiosis Warm Autoimmune Hemolytic Anemia
16A. Recognizing Sepsis as a Global Health Priority-A WHO Resolution
16B. A CRISPR Way to Diagnose Infectious Diseases
17. Typhoid Fever:: A Review
Section 6:: Miscellaneous (Geriatrics, genetics, and pregnancy related)
1. Associations of Fat and Muscle Tissue with Cognitive Status in Older Adults:: The AGES-Reykjavik Study
2. Frailty Status at Admission to Hospital Predicts Multiple Adverse Outcomes
3. Metabolic Syndrome and Insulin Resistance are Associated with Frailty in Older Adults:: A Prospective Cohort Study
4. Coexistence of Metallo-beta-lactamase-encoding Genes in Pseudomonas aeruginosa
5. Genetic Diversity Study of Various ?-lactamase-producing Multidrug-resistant Escherichia coli Isolates from a Tertiary Care Hospital Using ERIC-PCR
6. Characterization of Antimicrobial Resistance Markers and Their Stability in Salmonella enterica Serovar Typhi
7. Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
8. Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease
9. Asymptomatic Osteoporosis in Indian Geriatric Population
10. Current Scenario of Geriatric Fungal Infections:: A Prevalence Study from a Tertiary Care Hospital
11. SOFA Score and Critically Ill Elderly Patients
12. Continuous Glucose Monitoring in Pregnant Women with Type 1 Diabetes (CONCEPTT):: A Multicentre International Randomized Controlled Trial
13. Obesity and Gynaecological and Obstetric Conditions:: Umbrella Review of the Literature
14. Statistical Considerations for Randomized Controlled Trials [RCTs]-Understanding Superiority, Equivalence and Non-inferiority Designs
15. Molecular Minimal Residual Disease in Acute Myeloid Leukemia
16. Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis
17. Trial of Solanezumab for Mild Dementia Due to Alzheimers Disease
18. Why Geriatric Medicine? A Survey of UK Specialist Trainees in Geriatric Medicine
19. Will Maintenance of Oral Hygiene in Nursing Home Residents Prevent Pneumonia?
20. Diagnostic Accuracy of Novel and Traditional Rapid Tests for Influenza Infection Compared With Reverse Transcriptase Polymerase Chain Reaction:: A Systematic Review and Meta-analysis
21. Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism
22. The Relationship between Neutrophil to Lymphocyte Ratio and Metabolic Syndrome in Patients with Type 2 Diabetes
Section 7:: Nephrology and Hypertension
1. Prophylactic Hydration to Protect Renal Function from Intravascular Iodinated Contrast
Material in Patients at High Risk of Contrast-induced Nephropathy (AMACING):: A Prospective, Randomised, Phase 3, Controlled, Open-label, Non-inferiority Trial
2. Quantifying Postdonation Risk of ESRD in Living Kidney Donors
3. Kidney Outcomes Three Years after Bariatric Surgery in Severely Obese Adolescents
4. Food Insecurity, CKD, and Subsequent ESRD in US Adults
5. The Genetic Landscape of Renal Complications in Type 1 Diabetes
6. IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation
7. Novel Treatment Protocol for Ameliorating Refractory, Chronic Pain in Patients with Autosomal Dominant Polycystic Kidney Disease
8A. Effects of Empagliflozin on the Urinary Albumin-to-creatinine Ratio in Patients with Type 2 Diabetes and Established Cardiovascular Disease:: An Exploratory Analysis from the EMPA-REG OUTCOME Randomised, Placebo-controlled Trial
8B. Canagliflozin Slows Progression of Renal Function Decline Independently of Glycemic Effects
9. Single-nephron Glomerular Filtration Rate in Healthy Adults
10. Effects of Intensive BP Control in CKD
11. Intensified Multifactorial Intervention in Type 2 Diabetics with Microalbuminuria Leads to Long-term Renal Benefits
12. Tolvaptan in Later-stage Autosomal Dominant Polycystic Kidney Disease
13A. A Randomized Trial of Vitamin D Supplementation on Vascular Function in CKD
13B. Effects of Vitamin D Receptor Activation and Dietary Sodium Restriction on Residual Albuminuria in CKD:: The ViRTUE-CKD Trial
14A. Effect of Oral Methylprednisolone on Clinical Outcomes in Patients with IgA Nephropathy:: The TESTING Randomized Clinical Trial
14B. Targeted-release Budesonide versus Placebo in Patients with IgA Nephropathy (NEFIGAN):: A Double-blind, Randomised, Placebo-controlled Phase 2b Trial
15A. Multitarget Therapy for Maintenance Treatment of Lupus Nephritis
15B. Induction and Maintenance Immunosuppression Treatment of Proliferative Lupus Nephritis:: A Network Meta-analysis of Randomized Trials
16. Rituximab for Childhood-onset Refractory Nephrotic Syndrome (RCRNS) Study Group. Long-term Outcome of Childhood-onset Complicated Nephrotic Syndrome after a Multicenter, Double-blind, Randomized, Placebo-controlled Trial of Rituximab
17. Antibiotic Prophylaxis for Urinary Tract Infection-related Renal Scarring:: A Systematic Review
18. Effect of Human Leukocyte Antigen Mismatching on the Outcomes of Pediatric Kidney Transplantation:: A Systematic Review and Meta-analysis
19. Perinatal Diagnosis, Management, and Follow-up of Cystic Renal Diseases:: A Clinical Practice Recommendation with Systematic Literature Reviews
20. Mycophenolate Mofetil Is Inferior to Tacrolimus in Sustaining Remission in Children with Idiopathic Steroid-resistant Nephrotic Syndrome
Section 8:: Neurology
1. Global, Regional, and National Burden of Neurological Disorders During 1990-2015:: A Systematic Analysis for the Global Burden of Disease Study 2015
2. ILAE Classification of the Epilepsies:: Position Paper of the ILAE Commission for Classification and Terminology
3. Trial of Cannabidiol for Drug-resistant Seizures in the Dravet Syndrome
4. Bioequivalence between Generic and Branded Lamotrigine in People with Epilepsy:: The EQUIGEN Randomized Clinical Trial
5A. Investigations in GABAA Receptor Antibody-associated Encephalitis
5B. DPPX Antibody-associated Encephalitis:: Main Syndrome and Antibody Effects
6. Safety and Efficacy of Erenumab for Preventive Treatment of Chronic Migraine:: A Randomized, Double-Blind, Placebo-controlled Phase 2 Trial
7. Referral Practice, Reporting Standards, and the Impact of Dopamine Transporter Scans Done in a Tertiary Hospital
8. Risk Factors for Early Psychosis in PD:: Insights from the Parkinsons Progression Markers Initiative
9. Cluster-randomized, Crossover Trial of Head Positioning in Acute Stroke
10. Family-led Rehabilitation after Stroke in India (ATTEND):: A Randomized Controlled Trial
11. Predictors of Good Outcome after Endovascular Therapy for Vertebrobasilar Occlusion Stroke
12. Risk Factors, Vascular Lesion Distribution, Outcome and Recurrence of Strokes Due to Intracranial Atherosclerosis:: One Year Data from Hyderabad Stroke Registry
13. Prevalence and Risk Factors of Asymptomatic Carotid Artery Stenosis in Indian Population:: An 8?year Follow?up Study
14. Rapid Clinical Score for the Diagnosis of Tuberculous Meningitis:: A Retrospective Cohort Study
15. Low-dose Aspirin and Risk of Intracranial Bleeds
16. Trial of Pregabalin for Acute and Chronic Sciatica
17. Characteristics of Nerve Conduction Studies in Carpal Tunnel Syndrome
18. Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis
19. High-dose Immunosuppressive Therapy and Autologous HCT for Relapsing-remitting MS
Section 9:: Rheumatology and Immunology
1. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
2. Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis
3. Efficacy and Safety of Tofacitinib Monotherapy, Tofacitinib with Methotrexate, and Adalimumab with Methotrexate in Patients with Rheumatoid Arthritis (ORAL Strategy):: A Phase 3b/4, Double-blind, Head-to-head, Randomised Controlled Trial
4A. Tofacitinib or Adalimumab versus Placebo for Psoriatic Arthritis
4B. Tofacitinib for Psoriatic Arthritis in Patients with an Inadequate Response to TNF Inhibitors
5. Trial of Tocilizumab in Giant-cell Arteritis
6. Incident Myocardial Infarction Associated with Major Types of Arthritis in the General Population:: A Systematic Review and Meta-analysis
7A. Rheumatoid Arthritis Triple Therapy Compared with Etanercept:: Difference in Infectious and Gastrointestinal Adverse Events
7B. Rheumatoid Arthritis Patients with Continued Low Disease Activity have
Similar Outcomes Over 10 Years, Regardless of Initial Therapy 268
8. Patients with Seronegative RA Have More Inflammatory Activity Compared with Patients with Seropositive RA in an Inception Cohort of DMARD-naive Patients Classified According to the 2010 ACR/EULAR Criteria
9. EULAR Definition of Arthralgia Suspicious for Progression to Rheumatoid Arthritis
10. Mycophenolate Mofetil Versus Placebo for Systemic Sclerosis-related Interstitial Lung Disease:: An Analysis of Scleroderma Lung Studies I and II
11. Co-occurrence and Characteristics of Patients with Axial Spondyloarthritis Who Meet Criteria for Fibromyalgia:: Results from a UK National Register
12. A Cross-sectional Study of Cardiovascular Involvement in Systemic Lupus Erythematosus in an Urban Indian Tertiary Care Centre with Emphasis on 2-D Echocardiography
13. Pulmonary and Ear, Nose and Throat (ENT) Involvement in ANCA-associated Vasculitis at Diagnosis-Experience from a Tertiary Care Centre in North India
14. Etiology and Outcomes of Lower Limb Ulcers in Non-diabetic Patients, An Experience from Government Hospital in Western India
15. Effect of Disease-modifying Antirheumatic Drug Therapy on Immune Response to Trivalent Influenza Vaccine in Rheumatoid Arthritis
16. Clinical Experience with Two Etanercept Biosimilars in Indian Patients with Spondyloarthritis
17. Assessment of Extent of Skin Involvement in Scleroderma using Shear Wave Elastography
Index