Fetal & Neonatal Hematology, Oncology and Immunology

Section 1:: Fetal Hematology and Antenatal Diagnosis of Hematological Disorders

• Physiology of Hematopoiesis
• Developmental Hemostasis and Physiology ofHemostasis in the Fetus and the Newborn
• Granulocytes:: Development and Physiology
• Developmental Aspects of Platelets
• Fetal Anemia
• Thalassemia in the Fetus:: Prenatal Diagnosis
• Genetic Counseling for Hematological Disorders
• Fetal Hematological Disorders:: Future Ahead

Section 2:: RBC Disorders and Anemia in Newborn

• Developmental Erythropoiesis
• Normal Hematological Values and Variation in Newborn Periodwith Special Reference to Hb and RBC Parameters
• Effect of Nutritional Deficiency Anemia duringPregnancy on Fetus and Newborn
• Anemia of Prematurity
• Clinical Aspect of Immune Hemolytic Disease of Newborn
• Laboratory Management of ABO and Rh HemolyticDisease of the Fetus and Newborn
• Nonimmune Hemolytic Anemia
• Inherited Bone Marrow Failure Syndromes
• Polycythemia and Hyperviscosity Syndrome in Newborn

Section 3:: Coagulation Disorders in Newborn

• Congenital Coagulation Disorders in the Neonate
• Vitamin K Deficiency Bleeding
• Disseminated Intravascular Coagulation in the Neonatal Period
• Thrombophilia in Newborns

Section 4:: Platelets, Platelet Disorders and Approach to Bleeding in Newborn

• Approach to Neonatal Thrombocytopenia
• Neonatal Thrombocytopenia:: Syndromic Causes
• Qualitative Platelet Disorders
• Approach to a Bleeding Neonate

Section 5:: Neutrophil Disorders

• Neutrophilia
• Important Causes of Neutropenia Including Inherited Conditions::Diagnosis and Work-up
• Neutrophil Function Defects
• Management of Neutropenia and Infections

Section 6:: Fetal and Neonatal Malignancy

• Cancers in Infants
• Neonatal Leukemia
• Neonatal Liver Tumor
• Neuroblastoma
• Renal Tumors in Neonates
• Neonatal Soft Tissue Sarcomas
• Fetal and Neonatal Germ Cell Tumors
• Retinoblastoma and its Prenatal Screening
• Pharmacology of Anticancer Drugs in Neonate
• Challenges in Neonatal Malignancies

Section 7:: Blood Transfusion (Component Therapy) and Supportive Therapy

• Cellular Blood Components in Neonatal Practice
• Plasma and Its Derivatives
• Technical Aspects of Blood and Blood Components Transfusion including Leukodepletion and Irradiation
• Risk of Transfusion in Fetus and Neonate
• Hematological Growth Factors as Supportive Therapy

Section 8:: Immunological Disorders

• Introduction to Immunology
• Fetal and Neonatal Immunity
• Infections in Neonatal Period:: Primary Immunodeficiency Perspective
• Approach to Newborns with Immunodeficiency
• Neutrophil Functions and Disorders of Neutrophils in Newborns
• Combined T- and B-Cell Defects
• Primary Antibody Deficiencies
• Combined Immunodeficiencies with Associated or Syndromic Features
• Immune Dysregulation Syndromes
• Complement Disorders
• Autoinflammatory Syndromes
• Management of Specific Immunodeficiencies
• Neonatal Screening and Prenatal Diagnosis of Primary Immunodeficiency Disorders

Index