Principles & Practice of Assisted Reproductive Technology (3 Vols)

Volume 1:: Infertility
SECTION 1:: PHYSIOLOGY

• Anatomy and physiology of male & female reproductive system
• Ooogenesis and Folliculogenesis
• Physiology of Menstrual Cycle
• Human spermatozoa – Production and Migration
• The Human Sperm :: Its Contribution to Fertilization and embryogenesis
• Endometrial receptivity
• Embryo maternal dialogue and Implantation

SECTION 2:: REPRODUCTIVE ENDOCRINOLOGY

• Hyperprolactinemia and Thyroid disorders
• Hirsutism
• Fertility treatment in Primary and Secondary Amenorrhoea
• Luteal Phase defect
• Anovulatory infertility

SECTION 3:: MALE INFERTILITY

• Etiology and Pathophysiology of male infertility
• Clinical and Endocrinological evaluation of the infertile male
• The Microbiology of semen and Infections of the Male Genito urinary tract
• Sexual Dysfunction
• Cytogenetics of male infertility
• Role of sonography and doppler in male infertility
• Varicocele and its role in male infertility
• Medical Management of male infertility
• Management of Azoospermia
• Sperm Retrieval techniques

SECTION 4:: GENERAL OVERVIEW

• Patient selection and management
• Immunology in Infertility
• Environmental factors affecting fertility
• Declining fertility

SECTION 5:: FEMALE FACTOR INFERTILITY

• Evaluation of infertile female
• Uterine and Cervical factors in Infertility
• Tubal factors in Infertility
• Role of HSG and SSG in evaluating the fallopian tubes
• Infections and infertility
• Tuberculosis and Infertility
• Transvaginal sonography and Doppler in female Infertility
• Endoscopy in Infertility
• Assessment of ovarian reserve
• Endometriosis and Infertility
• Role of fibroids in infertility
• Reconstructive Surgeries enhancing infertility
• Obesity and Infertility
• Unexplained Infertility
• Fertility preservation in female patients

SECTION 6:: OVULATION INDUCTION

• Drugs for Controlled ovarian stimulation
• Super Ovulation Strategies in Assisted conception
• GnRH Agonists
• GnRH Antagonists
• Monitoring of ovulation induction
• Ovulation trigger
• Individualized stimulation protocol
• Mild stimulation protocols
• Role of LH in ovarian stimulation
• Progesterone in ovarian stimulation
• Prognosticating and Optimizing IVF outcome
• Luteal phase support

SECTION 7:: INTRAUTERINE INSEMINATION

• Intrauterine Insemination
• Optimizing success in IUI

SECTION 8:: ASSISTED REPRODUCTIVE TECHNIQUES

• Anaesthesia and IVF
• Oocyte retrieval
• Embryo Transfer

SECTION 9:: DILEMMAS IN ART

• Treatment strategies in poor responders
• Recurrent Implantation Failure
• Empty Follicle Syndrome
• Single Embryo Transfer
• Role of Aneuploidy screening in pre implantation embryos
• Epigenetics and AR

SECTION 10:: COMPLICATIONS OF ART

• Ovarian Hyperstimulation Syndrome
• Ectopic Pregnancy
• Latrogenic multiple pregnancy
• Fetal Reduction
• Oncogenic risks related to ART

SECTION 11:: THIRD PARTY REPRODUCTION

• Oocyte and Embryo Donation
• Oocyte Sharing Programmes
• Surrogacy
• Challenges faced in setting up a Surrogate house within the ICMR guidelines
• Adoption

SECTION 12:: MISCELLANEOUS

• Batch IVF
• Alternatives of ART
• Endometrial preparation in FET cycles

SECTION 13:: OUTCOME FOLLOWING ART

• Obstetric outcome following ART
• Outcome of children born through ART

SECTION 14:: GRIEF COUNSELLING

SECTION 15:: ETHICAL AND LEGAL ISSUES

• Ethical legal and social issues of modern ART treatment

SECTION 16:: FUTURE CLINICAL APPLICATIONS

• Endometrial stem cells and reproduction

Volume 2:: IVF and Related Procedures

SECTION 1:: ANDROLOGY

• Semen Analysis in 21^st Century Medicine—A Paradigm Shift
• Sperm Chromatin Assessment
• Ejaculatory Failure
• Sperm Preparation in Assisted Conception:: Laboratory Techniques
• Semen Banking

SECTION 2:: EMBRYOLOGY

• History of In Vitro Fertilization
• In Vitro Fertilization and Embryo Transfer
• Intracytoplasmic Sperm Injection
• Analysis of Fertilization
• Morphological Assessment of Oocyte and Embryo
• Blastocyst Culture and Transfer 
• Advantages and Disadvantages of Embryo Transfer on Day 2, Day 3 and Blastocyst Stage
• Embryo Transfer Techniques
• Cryopreservation of Oocytes and Embryos by Slow Freezing Method
• Oocyte Vitrification
• Vitrification

SECTION 3:: ADVANCES IN ASSISTED REPRODUCTVE TECHNOLOGIES

• Assisted Hatching
• Embryo Biopsy for Preimplantation Genetic Diagnosis
• In Vitro Maturation of Oocytes:: A Practical Approach
• Ovarian Tissue Cryopreservation
• Time Lapse Video for Assessing the Embryos
• Polarization Microscopy
• OMICS
• IMSI and its Clinical Significance
• Microfluidics in ART

SECTION 4:: ETHICAL AND LEGAL ISSUES

• Certification and Accreditation-Relevance to an IVF Center
• Accreditation of an ART Laboratory

SECTION 5:: LABORATORY MANAGEMENT

• Setting-up an ART Laboratory
• Quality Control of IVF Laboratory
• Culture Systems
• Micromanipulators
• Troubleshooting in ART

Volume 3:: Atlas of Embryology

• Oocyte Cumulus Complex Evaluation
• Oocyte Nuclear Maturity Evaluation
• Oocyte Dysmorphisms
• The Sperm
• Normal Embryo Development
• Embryo Scoring
• In Vitro Fertilization/Intracytoplasmic Sperm Injection
• Advanced Techniques
• Cryopreservation
• Assisted Reproductive Technology Lab Setting