Diastology

• Part I: Basic Determinants of Diastolic Function

• Molecular, Gene, and Cellular Mechanis

Pathophysiology of Heart Failure With a Preserved Ejection Fraction: Measurements and Mechanisms Causing Abnormal Diastolic Function

Role of the Pericardium in Diastolic Dysfunction

Left Atrial Function: Basic Physiology

Physical Determinants of Diastolic Flow

Ventricular-Arterial Interaction in Patients With Heart Failure and a Preserved Ejection Fraction

Part II: Diagnosis of Heart Failure With Preserved Ejection Fraction

General Principles, Clinical Definition, Epidemiology, and Pathophysiology

Invasive Hemodynamic Assessment in Heart Failure With Preserved Ejection Fraction

Two-Dimensional and Doppler Evaluation of Left Ventricular Filling, Including Pulmonary Venous Flow Velocity

Evaluation of Diastolic Function by Tissue Doppler, Strain, and Torsion Analysis

Color M-mode Doppler

Assessment of Left Atrial Size and Function

Evaluation of Intracardiac Filling Pressures

Evaluation of Right Ventricular Diastolic Function

Evaluation of Diastolic Function by Cardiac Magnetic Resonance Imaging

Evaluation of Diastolic Function by Radionuclide Techniques

Diastolic Echocardiographic Examination

Diastology Stress Test

ASE/EACVI Diastolic Guidelines: Strength and Limitations

Part III: Cardiac Diseases With HFpEF

Hypertension and Its Relation to Heart Failure With a Preserved Ejection Fraction

Valve Disease

Stage D Heart Failure With Preserved Ejection Fraction, Heart Transplantation, and Mechanical Circulatory Support

Primary Restrictive, Infiltrative, and Storage Cardiomyopathies

Coronary Artery Disease

Hypertrophic Cardiomyopathy

Pericardial Diseases: Constrictive Pericarditis and Pericardial Effusion

Diastolic Function in Children and in Children With Congenital Heart Disease

Diabetes Mellitus

Part IV: Emerging Topics in HFpEF

Global and Regional Systolic Function of the Left Ventricle

Chronotropic Incompetence and Pacing in HPEF Heart Failure with Preserved Ejection Fraction

Aging and Heart Failure With Preserved Ejection Fraction

Perioperative Assessment of Diastolic Function

Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction

Part V: Treatment of HFpEF

General Treatment of Heart Failure With Preserved Ejection Fraction and Randomized Trials

Echo-Based Approach to the Management of Heart Failure With Preserved Ejection Fraction

Future Therapies in HFpEF

Part VI: Cases of Diastolic Heart Failure

Cases of Diastolic Heart Failure