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Dr. Arnold Katzs internationally acclaimed classic is now in its thoroughly revised Fourth Edition, incorporating the latest molecular biology research and extensively exploring the clinical applications of these findings. In a readable style enhanced by more than 400 diagrams, Dr. Katz provides a comprehensive overview of the physiological and biophysical basis of cardiac function, beginning with structure and proceeding to biochemistry, biophysics, and pathophysiology in arrhythmias, ischemia, and heart failure. This edition features a new clinical applications section and expanded chapters on the ischemic heart and heart failure.
Opis
STRUCTURE, BIOCHEMISTRY, AND BIOPHYSICS
Structure of the Heart and Cardiac Muscle
Energetics and Energy Production
Energy Utilization (Work and Heat)
The Contractile Proteins
The Cytoskeleton
Active State, Length-Tension Relationship, and Cardiac Mechanics
Excitation-Contraction Coupling:: Extracellular and Intracellular Calcium Cycles
SIGNAL TRANSDUCTION AND REGULATION
Signal Transduction:: Functional Signaling
Signal Transduction:: Proliferative Signaling
Regulation of Cardiac Muscle Performance:: Functional and Proliferative Mechanisms
NORMAL PHYSIOLOGY
The Heart as a Muscular Pump
The Working Heart
Cardiac Ion Channels
The Cardiac Action Potential
CLINICAL PHYSIOLOGY
The Electrocardiogram
Arrhythmias
The Ischemic Heart
Heart Failure