In this issue of Interventional Cardiology Clinics, guest editor Dr. Thomas Smith brings his considerable expertise to the topic of Multi-Modality Interventional Imaging. Top experts in the field discuss key topics such as tricuspid valve TEER guidance with transesophageal echocardiography and ICE; 4D ICE:: the next frontier in structural imaging guidance; multiplanar reconstruction:: advanced 3D TEE techniques to guide complex structural procedures; CT procedure planning for transcatheter mitral valve replacement; use of CT for LAAO procedure planning and post-procedure assessment; and more.