A volume in the Molecular and Cellular Neurobiology series.This book reviews the recent advances in our understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting and anchoring of the protein complexes making up the most important ion channels and receptor families, fundamental to synaptic function. Improved understanding of these processes is expected to reveal novel therapeutic targets relevant to a range of disease states.The first section of the book contains three chapters dealing with cation channels and provides an accessible, succinct and comprehensive account of what is known about the structures and the assembly and targeting of these multimeric proteins. The focus of the book then moves on to cover ligand-gated ion channels with two chapters on acetylcholine receptors. The final section of the book contains four chapters covering the excitatory and inhibitory amino acid receptors. Receptor and Ion-Channel Trafficking provides an integrated overview of the significant recent advances in the field of molecular neurobiology and will be essential reading for all researchers in neuroscience, neurobiology, biochemistry, cellular and molecular biology.
Ion Channels; Voltage-gated sodium channels; The assembly and targeting of potassium channels; Assembly and targeting of voltage-dependent calcium channels; Acetylcholine Receptors; Targeting of acetylcholine receptors to the postsynaptic endplate of the nerve-muscle synapse; Assembly and targeting of neuronal nicotinic acetylcholine receptors; Amino Acid Receptors; AMPA/kainate receptors; NMDA receptor targeting; Structure, assembly and targeting of glycine receptors; GABAA and GABAC receptors:: regulation of assembly, localization, clustering and turnover;
Komentarze (0)
Chwilowo nie możesz polubić tej opinii
Zgłoś komentarz
Czy jesteś pewien, że chcesz zgłosić ten komentarz?
Zgłoszenie wysłane
Twój komentarz został wysłany i będzie widoczny po zatwierdzeniu przez moderatora.
Dostawa
Płatność
Zwroty
