In this issue of Immunology & Allergy Clinics, guest editor Dr. Peck Ong brings his considerable expertise to the topic of Allergic Skin Diseases. Top experts provide an updated clinical guide in the management of atopic dermatitis, chronic urticaria, itch and cutaneous mastocytosis. Articles also cover the emerging area of prevention of atopic dermatitis. Discussions include the mechanisms IgE development in atopic dermatitis, novel methods for predicting the development of atopic dermatitis in infants, targeting skin barrier defects, pollutant triggers and microbiome as potential treatments.