This book compiles insights from eight years of symposia held alongside the annual meetings of the Scoliosis Research Society. Featuring contributions from leading experts in genetics, biomechanics, metabolism, and related disciplines, this volume synthesizes the latest theories and evidence on the origins and progression of adolescent idiopathic scoliosis (AIS). This book is the first of its kind to present this comprehensive perspective on the etiology of AIS. It is intended for clinicians, researchers, and students who seek a deeper understanding of this complex and often misunderstood condition.