Primary Sjögrens syndrome is a rheumatic disease affecting around 0.1-0.2% of the adult female population and can result in significant disability without adequate therapy. Diagnosis is often delayed and suggested therapies may not be optimal, and a multidisciplinary approach that includes rheumatologists, ophthalmologists, oral medicine physicians, and others is important to patient management. This volume summarises current understanding of the pathogenesis of the disease, including advances in the genetics of Sjögrens syndrome. Chapters cover disease mechanisms, clinical diagnosis and assessment, secondary Sjögrens syndrome, the role of laboratory investigations, and imaging. A therapy-based section covers topical oral and ocular therapies, and the role of steroids and biologics are also addressed. Sjögrens Syndrome is a practical concise pocketbook featuring key points and illustrations showing important mechanisms of disease and pathways of care. The book will be of interest to trainees in rheumatology, ophthalmology, and oral medicine/surgery; specialist practitioners and therapists involved in the care of patients with Sjögrens syndrome; and primary care physicians, dentists, and other specialists such as ENT physicians.
Epidemiology, genetics, and disease burden; Diagnosis and clinical assessment; Oral features; Ocular features; Fatigue, pain, and quality of life; Systemic features (extra-glandular) features; Evidence-based evaluation and therapies; Lymphoma: Pathogenesis, prediction, and therapy; Case Studies;
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