This book is a user-friendly book directed at practising general otolaryngologists, developmental biologist, geneticists and researcher focused on understanding the inner ear structure and biology. This book is both comprehensive, easy to follow and each chapter is short, informative and self-contained. It will provide an overview of four main topics related to inner ear development, hearing loss and clinical remedies, genetics of deafness in the post genomic era. The overall objective of this book is to bring together noted otolaryngologists and scientists from the perspective of complementary disciplines for a review of the current state of knowledge and available clinical therapies, genetics testing practices in various populations and molecular components of inner ear and their function in sound perception.
Preface; The Birth of a Mechanosensor:: Development of Vertebrate Hair Cells; Tight Junctions-Barriers Against Hair Cell Toxicity & Hearing Loss; Usher & Bardet-Biedl Syndrome Proteins:: New Pieces in the Planar Cell Polarity Puzzle; Autoimmune Inner Ear Disease (AIED); Labyrinthine Aplasia, Microtia, & Microdontia (LAMM) Syndrome & FGF3 Mutations; Social Implications of Cochlear Implantation in Children.
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