Key Trials of the Decade, An Issue of Interventional Cardiology Clinics

This issue of Interventional Cardiology Clinics, guest edited by Editor-in-Chief Matthew J. Price, will focus on Key Trials of the Decade. Trials discussed in this issue will include:: Physiology over Angiography to determine lesion severity:: The FAME trials; Percutaneous Coronary Intervention or surgery for multivessel disease:: The SYNTAX trial at 10 years; Percutaneous Coronary Intervention or surgery for unprotected left main disease:: The EXCEL trial at 5 years; Complete or Incomplete Revascularization for ST-Elevation Myocardial Infarction:: the PRAMI trial and beyond; Abbreviated Dual Antiplatelet Therapy after PCI in High Bleeding Risk Patients:: LEADERS-FREE and ONYX ONE; Transcatheter treatment of functional mitral regurgitation in patients with heart failure:: The COAPT trial; Manual thrombectomy in Primary Percutaneous Coronary Intervention:: Lessons learned from TOTAL; Paradigm shifts in the treatment of aortic stenosis:: The PARTNER Trials experience; COURAGE and ORBITA in context:: PCI for chronic stable CAD; SIMPLICITY to RADIANCE:: Interpreting the past and mapping the future of renal denervation; From WOEST to AUGUSTUS:: Dual Therapy after PCI; The ISCHEMIA Trial:: Background, Design, Outcomes and Clinical Interpretation.