Marks' Basic Medical Biochemistry: A Clinical Approach

Section One:: FUEL METABOLISM 1:: Metabolic Fuels and Dietary Components 2:: The Fed or Absorptive State 3:: Fasting

Section Two:: CHEMICAL AND BIOLOGICAL FOUNDATIONS OF BIOCHEMISTRY 4:: Water, Acids, Bases, and Buffers 5:: Structures of the Major Compounds of the Body 6:: Amino Acids in Proteins 7:: Structure-Function Relationships in Proteins 8:: Enzymes as Catalysts 9:: Regulation of Enzymes 10:: Relationship between Cell Biology and Biochemistry 11:: Cell Signaling by Chemical Messengers

Section Three:: GENE EXPRESSION AND THE SYNTHESIS OF PROTEINS 12:: Structure of the Nucleic Acids 13:: Synthesis of DNA 14:: Transcription:: Synthesis of RNA 15:: Translation:: Synthesis of Proteins 16:: Regulation of Gene Expression 17:: Use of Recombinant DNA Techniques in Medicine 18:: The Molecular Biology of Cancer

Section Four:: FUEL OXIDATION AND THE GENERATION OF ATP 19:: Cellular Bioenergetics:: ATP and O2 20:: Tricarboxylic Acid Cycle 21:: Oxidative Phosphorylation and Mitochondrial Function 22:: Generation of ATP from Glucose:: Glycosis 23:: Oxidation of Fatty Acids and Ketone Bodies 24:: Oxygen Toxicity and Free Radical Injury 25:: Metabolism of Ethanol

Section Five:: CARBOHYDRATE METABOLISM 26:: Basic Concepts in the Regulation of Fuel Metabolism by Insulin, Glucagon, and Other Hormones 27:: Digestion, Absorption, and Transport of Carbohydrates 28:: Formation and Degradation of Glycogen 29:: Pathways of Sugar Metabolism:: Pentose Phosphate Pathway, Fructose, and Galactose Metabolism 30:: Synthesis of Glycosides, Lactose, Glycoproteins, and Glycolipids 31:: Gluconeogenesis and Maintenance of Blood Glucose Levels

Section Six:: LIPID METABOLISM 32:: Digestion and Transport of Dietary Lipids 33:: Synthesis of Fatty Acids, Triacylglycerols, and the Major Membrane Lipids 34:: Cholesterol Absorption, Synthesis, Metabolism, and Fate 35:: Metabolism of the Eicosanoids 36:: Integration of Carbohydrate and Lipid Metabolism

Section Seven:: NITROGEN METABOLISM 37:: Protein Digestion and Amino Acid Absorption 38:: Fate of Amino Acid Nitrogen:: Urea Cycle L39:: Synthesis and Degradation of Amino Acids 40:: Tetrahydrofolate, Vitamin B12, and S-Adenosylmethionine 41:: Purine and Pyrimidine Metabolism 42:: Intertissue Relationships in the Metabolism of Amino Acids

Section Eight:: TISSUE METABOLISM 43:: Actions of Hormones Regulating Fuel Metabolism 44:: The Biochemistry of the Erythrocyte and Other Blood Cells 45:: Blood Plasma Proteins, Coagulation and Fibrinolysis 46:: Liver Metabolism 47:: Metabolism of Muscle at Rest and During Exercise 48:: Metabolism of the Nervous System 49:: The Extracellular Matrix and Connective Tissue

Appendix:: Answers to Review Questions
Index